38 Nutritional and Nutraceutical Potential of Licorice (Glycyrrhiza glabra)
Ishrat Majid, Khan Nadiya Jan, Gulzar Ahmad Nayik, Vikas Nanda
Abstract
Due to rapidly increasing knowledge on nutrition and medicine, concepts about food and health has dramatically changed and resulted in consumption of nutraceuticals and natural plant foods.Use of nutritional therapy and phytotherapy have become progressively popular to improve health, and to prevent and treat diseases. Plants have long history of their uses as ingredients of human nutrition and folk medicine,because of availability of huge array of high-value components and multiple-activity bio-actives. “Licorice” means “sweet root” in Greek is a plant of ancient origin, indigenous to Southern Europe and Asia Minor. Most of the supply comes from former USSR, Spain, Turkey, Syria, Iraq and Afghanistan, with total production between 40,000 and 50,000 tonnes per annum. The chemical constituents of the roots include several bioactive compounds, such as glycyrrhizin (~16%), different sugars (up to 18%) ,flavonoids, saponoids,sterols, starches, amino acids, gums and essential oils. A large number of clinical and experimental studies reported its useful biological properties such as antioxidant, immunomodulatory, cardioprotective, anti-inflammatory, anti-viral and anticancer effects. It is useful in anaemia, gout, asthama,ulcers, sore throat, tonsillitis, diabetes, tuberculosis, flatulence, diarrhea, sexual debility, epilepsy, hyperdypsia, fever, coughs, skin diseases, eye diseases, swellings,constipation, rheumatism, acidity, leucorrhoea, bleeding, jaundice, hiccough, hoarseness, bronchitis.Recently, it is reported to have neurological properties such as antidepressant, anxiolytic, and anticonvulsant effects. The most abundant minerals present are calcium, sodium, phosphorus, potassium and iron. Licorice extracts and its principle component, glycyrrhizin, have extensive use in foods,as a natural sweetener and flavoring agent in beverage, confectionery, tobacco and pharmaceutical industry. It is in great demand globally as medicinal and nutritional supplement due to it's wide range of properties, which also indicates that in future the plant could serve as a “lead” for the development of novel agents having good efficacy in various disorders.
Abstract
Due to rapidly increasing knowledge on nutrition and medicine, concepts about food and health has dramatically changed and resulted in consumption of nutraceuticals and natural plant foods.Use of nutritional therapy and phytotherapy have become progressively popular to improve health, and to prevent and treat diseases. Plants have long history of their uses as ingredients of human nutrition and folk medicine,because of availability of huge array of high-value components and multiple-activity bio-actives. “Licorice” means “sweet root” in Greek is a plant of ancient origin, indigenous to Southern Europe and Asia Minor. Most of the supply comes from former USSR, Spain, Turkey, Syria, Iraq and Afghanistan, with total production between 40,000 and 50,000 tonnes per annum. The chemical constituents of the roots include several bioactive compounds, such as glycyrrhizin (~16%), different sugars (up to 18%) ,flavonoids, saponoids,sterols, starches, amino acids, gums and essential oils. A large number of clinical and experimental studies reported its useful biological properties such as antioxidant, immunomodulatory, cardioprotective, anti-inflammatory, anti-viral and anticancer effects. It is useful in anaemia, gout, asthama,ulcers, sore throat, tonsillitis, diabetes, tuberculosis, flatulence, diarrhea, sexual debility, epilepsy, hyperdypsia, fever, coughs, skin diseases, eye diseases, swellings,constipation, rheumatism, acidity, leucorrhoea, bleeding, jaundice, hiccough, hoarseness, bronchitis.Recently, it is reported to have neurological properties such as antidepressant, anxiolytic, and anticonvulsant effects. The most abundant minerals present are calcium, sodium, phosphorus, potassium and iron. Licorice extracts and its principle component, glycyrrhizin, have extensive use in foods,as a natural sweetener and flavoring agent in beverage, confectionery, tobacco and pharmaceutical industry. It is in great demand globally as medicinal and nutritional supplement due to it's wide range of properties, which also indicates that in future the plant could serve as a “lead” for the development of novel agents having good efficacy in various disorders.