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Spongiform encephalopathy

Spongiform encephalopathy is an infectious disease of animals caused by prion proteins and characterized by presence of vacuoles in brain.

Etiology

• Prion proteins

• Sheep – Scrapie or Ovine spongiform encephalopathy

• Cattle - Bovine spongiform encephalopathy (Mad cow disease)

• Feline encephalopathy

Pathogenesis

Scrapie is also known as ovine spongiform encephalopathy. The principle means of transmission of disease is from infected mother to their lambs early in life; placental transmission has also been reported. The incubation period of disease is very long (2-5 year). The clinical form is restricted in adults. The prion proteins (PrP) occur normally in the central nervous system of all domestic animals and man bounded with neuronal surface. Animal susceptible to prion disease have a gene (PrP gene) which encodes for normal “Prion protein (PrP)” or “cellular prion protein (PrPc). In scrapie prion protein (PrPsc)/ scrapie associated fibril protein (SAI) is generated which are resistant for protease digestion. Accumulation of PrPsc in neural tissues appears to be the cause of the pathology in prion disease. When prion protein contaminated meat and bone meal are fed to the cattle as part of their concentration, the agent (prion) got introduced into cattle. Prion protein (PrP) on reaching brain slowly and progressively converted into and abnormal form (PrP sc) and this abnormal protein causes development of lesions including vacuolation in nerve cells.

    Q.1.    What are the most common isolated environmental Streptococci from mastitis cases?
    Ans.    Streptococcus uberis and Streptococcus dysgalactiae.

    Q.2.    What are the common sources of environmental Streptococcus uberis in a herd?
    Ans.    The common sources are bedding materials, lips, nostrils and abdominal skin of cows.

    Q.3.    What are the common sources of environmental Streptococcus dysgalactiae?
    Ans.    The common sources are tonsils, mouth, vagina and mammary gland of cows.

    Q.4.    Why incidence of Streptococcus uberis is highest just prior to calving?
    Ans.    The important reasons are the excessive accumulation of milk due to lack of milking, lack of keratin plugs from the streak canal and immunosuppression at periparturient period.

    Q.5.    The cattle fly sometimes involves in persistent bacterial contamination on teat of a cow. Mention the name of the cattle fly.

The lymphatic system is a part of circulatory system and a vital part of the body’s immune system. It is comprised of lymph vessels, lymph ducts, and lymph nodes that move the lymph from tissues to the blood stream and the organs such as the spleen, thymus and bone marrow that produce the lymphocytes and white blood cells. Lymph is very similar to blood plasma. During circulation through the body, the blood reaches to the capillaries at the interstitial spaces. The plasma of the blood is filtered through the capillary wall. The fresh oxygen along with nutrients, hormones and other necessary fluid matters from this plasma are released in to the interstitial fluid and about 85 per cent of the plasma along with the carbon dioxide and metabolic wastes, return into the circulation through the capillary walls. The remaining 15 per cent of the plasma along with the debris of other waste products and the lymphocytes constitutes the lymph which is returned to the circulation through an accessory route of lymphatic vessels and lymph nodes constituting the lymphatic system.

Lymph Vessels: The lymph vessels start as finger-like blind ending thin walled lymph capillaries in the interstitial connective tissue. These capillaries form a network and drain into the thicker walled collecting lymph vessels, lymph ducts and lymphatic trunks. Finally the larger lymph trunks and ducts empty their content the lymph into the cranial vena cava at the thoracic inlet. The lymph vessels contain numerous valves with one or two leaflets preventing the back flow of lymph through the lymph vessels. During its course in a centripetal direction through the lymph vessel, the lymph of each lymph vessel has to pass through at least one lymph node prior to its entry into the blood circulation. As a result there lies a chain of lymph nodes on the pathway of lymph vessels in the body.

1. Botanical Name : Pyrus serotina Rehd.

2. Family : Pomaceae

3. Common Name : Wild pear (large-fruited type)

4. Name in Indian languages

Bada kainth, Shiara, Zarenth (Himachali), Shiara, Garmehal (Kumaoni).

5. Description

The trees of Pyrus serotina is found throughout the mid-hill region of Himalaya. The population of this species is very less as compare to Pyrus pashia. The fruits of this species are larger and less gritty. It is cold-hardy, tolerate low temperatures when dormant. It also has lower chilling requirements than most other.

6. Origin and distribution

It is native of central and East Asia form . It found in North Western Himalayan region.

The calyx may be either half or entirely broken. The petals are stripped of their support, which contributes to the petals being bent down. The continuity of the form and arrangement of the flower is thus lost. Splitting, particularly where light and temperature fluctuate is correlated with weather. By maintaining the night temperature at 5 ° F, some reduction in splitting can be achieved. More calyx splits were caused by high plant density per unit area. 

Observation recording: Students are advised to visit the Safeda plantation for collection of stem cuttings then raised in polythene bags and record the various nursery practices and conduct tending operations in Mahogany plantation.

Indication: Rehabilitation of downer animal

Poultry meat-50 g for each method
Cook the poultry meat according to the methods given in the table and record the cooking effects

Participatory curriculum reorientation awareness-raising workshop for key stakeholders: In the present study focus group discussion and workshops were conducted to know the effectiveness of present curriculum of extension education with different stakeholders (Students UG, PG and Ph.D, Extension teachers, Field extension workers and farmers). Data were collected by using schedules regarding the important contents of present curriculum and most important for extension workers in the present situation to be included in curriculum

Reagents

Nuclease-Free Water: 14µl

10X Restriction Buffer: 2µl

Acetylated BSA (1mg/ml): 2µl

DNA (~1µg): 1µl

Restriction Enzyme (10u): 1µl

Final Volume: 20µl

1. Botanical Name : Rourea minor (Gaertn.) Alston

2. Family : Connaraceae

3. Common Name : Cow Vine, Big-leaved Rourea

4. Name in Indian languages

Cheriyamarikunni, Kuriel (Malayalam), Puli pan (Kodwa), Hulimajge hannu (Kannada).

5. Description

It is a large woody climbing shrubs of family Connaraceae. Stem is black. Leaves are compound with 3-7 leaflets. Flowers in axillary panicled cymes.The fruits ripe in June –August. Whole fruit expect the rind and seed is consumed at ripe stage. It is rarely found. Rourea minor is a vigorous climbing shrub producing stems up to 25 metres long that climb into the surrounding vegetation.Although poisonous, the plant is sometimes harvested from the wild for local use in traditional medicine.

4.1. Highlights of the report on number and area of operational holdings (2015-16)

Total number of operational holdings in the country has increased from 138 million ha in 2010-11 to 146 million ha 2015-16 i.e. an increase of 5.33%.

Number of operational holders in different states

Uttar Pradesh (23.82 million ha)

Bihar (16.41 million ha)

Maharashtra (14.71 million ha)

Madhya Pradesh (10.00 million ha)

Karnataka (8.68 million ha)

Smaller leaves are produced and finally a rosette is formed. Internodal length reduction and apex-tapering of the stem. Most of the nuts are tiny and deformed, assuming they are produced. Drainage is poor and soil and pan/hard clay pan fertility are low.

Observation recording Lay the quadrats with the help of rope. Identify all the plant species, and count their number in each quadrat, dbh

Takes clean, washed and edible fish-50-100 g for each method of cooking. And cook the fish according to the methods given table and record the characteristics of cooked fish.