eChapters

True/False

Q.1.    In many epidemiological studies with substantial follow up time, it is very often an interest to study the time taken for a particular event to occur.
Q.2.    The time taken for death or graft failure since transplant, time taken for relapse after treatment, time to death after treatment etc. are examples for survival time.

True/False

Q.1.    The accuracy of the measurement refers to how close the measured value is to the true value.
Q.2.    The precision refers to how close a set or group of measurements are together.
Q.3.    If the processes of measurement are repeated under identical condition, then precision explains that up to what extent these repeated values are reliable.

True/False

Q.1.    Demographic data and vital statistics are important tools for researchers, epidemiologists, health planners and health professionals.
Q.2.    The distribution of people across different geographic regions is known as population density.

True/False

Q.1.    In many clinical research studies, the regression analysis is used to develop models for prediction of an outcome from one or more explanatory variables.
Q.2.    Now a days, the linear, logistic and Cox (proportional hazards) regression models are used frequently in medical research.

True/False

Q.1.    The precision of an estimator increases as the sample size increases.
Q.2.    Statistical power is the probability that a statistical test will indicate a significant difference is true i.e. it is the probability of taking correct decision.

Abstract

Dietary phytochemicals and herbal medicines are under intensive investigation for their potential as chemopreventive agents against various diseases due to the wide variety of microbial and plant functionally relevant secondary metabolites. The chemical diversity of phytochemicals, as well as phytochemicals and complex metabolic interactions between the biological systems may exceed the capacity of the platforms of traditional analysis, and therefore pose major challenges in the study of chemopreventive phytochemical compounds.

Abstract

Biotechnology offers an opportunity to exploit the cell, tissue, organ or entire organism by growing them in vitro and to genetically manipulate them to obtain desired compounds. It plays a pivotal role in search for alternatives to production of desirable biomedical compounds. There are several approaches have been used to increase the yield of metabolites from cell cultures such as manipulation of nutrient medium, application of exogenous growth stimulators, chemical treatment, precursor feeding, elicitation, transformed cultures, metabolic engineering, micropropagation, bioreactor cultures and etc.

Abstract

Quercus species of family Fagaceae are very important from both economic and ecological perspectives. These exhibit irregular fruiting, and produce seeds recalcitrant to storage, thereby difficult to propagate through conventional procedures. Again because of their very difficult to root nature, extremely limited success has been observed in vegetative propagation. Application of new technological approaches like in vitro propagation may be of interest for accelerating tree improvement programs to these hardwood species. This review provides a summary of the advancement in the application of in vitro propagation to oak species of Kumaun West Himalaya India.

Abstract

Bamboo is nature’s unique gift to mankind. It has tremendous scope for use in eco-friendly agro-forestry programmes, to bring marginal lands into use. The requirement for bamboo is increasing for various traditional and industrial requirements. In India almost 99% of annual bamboo production comes from the natural forests and only about 1% is derived from plantations.

Abstract

Bacilli, a group of endospore forming bacteria present in soil, contribute directly or indirectly to crop productivity. Bacilli have many physiological unique traits like multilayered cell wall, stress resistant endospore formation, secretion of peptide antibiotics, peptide signal molecules, extracellular enzymes, which make them ubiquitous and assist to their survival under adverse environmental conditions for long time.

Abstract

Biosurfactants (BS) are amphiphilic compounds produced by microorganisms mainly bacteria and are known to contain hydrophobic and hydrophilic moieties that play a major role in reducing surface tension (ST) and interfacial tensions between individual molecules. Chemically, BS is a complex molecules consisting of lipopeptides, glycolipids, polysaccharide protein complex, fatty acids and phospholipids. They are known for their biodegradability, low toxicity, and renewable nature.

Abstract

Thermophiles mainly harbor in highly temperate environments such as hydrothermal vents, hot springs, fumaroles etc. The main importance of thermophiles is due to their thermostable proteins, enzymes and their adaptive mechanisms at higher temperature which are very useful for industrial applications. The main rationale behind this research was to isolate industrially important thermophilic bacteria from the Hot Springs of Sikkim which can be used as tools for genetic engineering and vector based research activities.

Abstract

Since the beginning of the civilization, medicinal plants have been used to prevent and treat various ailments. At present, most of the pharmaceutical/ nutraceutical industries highly depend on wild medicinal plants for the supply of raw materials for extraction of bioactive compounds. As medicinal plants receive increased scientific and commercial attention, there is increasing pressure on the wild medicinal plant populations.

Abstract

Modern world is experiencing energy insecurity because of extreme population pressure and depleting energy resources. Fossil fuels though have highly applauded for contributing to today’s development, are non renewable energy and debated for not sustainable. This has posed serious challenges to the scientific fraternity for finding the suitable alternatives. A cheap, eco-friendly, sustainable or renewable type of energy is visualized for development with added advantage of mitigating green house gases.

Abstract

Nanotechnology is an emerging field that offers various potential applications in the areas of agriculture, health and medicine. Recent advances in the design and synthesis of nano-materials aids for developing sophisticated nano-devices for clinical research and practice. Applications of nano materials in medicine includes disease diagnosis, early prognosis, detection of pathogens, tumor detection, tissue engineering, target  specific drug delivery,  development of  biomaterials  for oral health  and understanding of cellular mechanisms in live cells using molecular imaging.

Abstract

Cancer is a potent disease causing nearly 6 million deaths per year worldwide. There are a number of cancers such as skin, brain, lung, breast, stomach, colon and blood cancer caused due to number of factors like unbalancing of hormones, smoking etc. Cancer could be treated by chemotherapies or through irradiation therapies.

Abstract

As we have entered in the post genomic era where we have successfully completed the full genome sequencing of many important crop species and now the future challenge is to ascertain the functions of all genes present in plant genome.

Abstract

Meta analysis quantitatively summarizes the findings of a large collection of individual experiments. It is a powerful statistical tool since it integrates a vast literature and thus includes large sample size. It leads to a stronger conclusion than traditional literary review as studies are analyzed applying statistical methods. Meta- analysis is increasingly being applied in different fields of biological sciences. It has been emerged as an independent subfield of modern health science researches as in this field very few studies achieve statistical power in isolation. Meta- analysis has also become an integral part of plant science research, e.g., agricultural research, ethnobotanical research, tea and health science research etc. Meta-analysis has few limitations although rigorously conducted meta- analyses are considered more valuable than any single study contributing to the analysis.

1.1 Water and its Importance

Water has played a crucial role in sustainace of lives of all living beings including animals, plants and human beings in this earth since time immemorial. It is there since the creation of the nature and will probably remain till the destruction of the nature. It is used in multifarious uses including domestic, industrial, agricultural, recreational and many other uses. It occurs in the nature in practically three forms i.e. solid, liquid and gaseous forms. All the three forms are important to living beings; but the liquid form of water is more beneficial. The weight of the water helps in running hydroelectric turbines, the density of water helps in floating the ships, the steam energy produced by heating the water helps to run the locomotives and thus is beneficial in many ways. It is considered as the most important resource of the society. It has become part and partial in our life so that we cannot live without water. That is why water is called as life.

2.1 Introduction

Precipitation is the general term for all forms of moisture emanating from clouds and then ultimately falling on the land surface. It is the total supply of water derived from the atmosphere in the forms of rain, snow, hail, mist, dew, sleet, fog etc. The liquid form of precipitation is called as rainfall whereas the frozen forms of precipitations are snow, hail and sleet. Of all the different forms of precipitation, rain and snow are the two dominant factors that contribute maximum amount of water. In Indian condition, rainfall is the most important form of precipitation that contributes the highest amount of water causing stream flow. Unless otherwise stated, the term rainfall will be used in this book synonymously with precipitation. It is the primary input vector of the hydrologic cycle. Generally it is expressed as the depth water on a horizontal surface over any specified time interval. If the specified time interval is day, then the amount of precipitation is called as daily precipitation. Similarly, the precipitation being contributed over time interval of a month, season and year is termed as monthly, seasonal or annual precipitation. Its form and quantity are influenced by the action of different climatic factors such as wind, temperature and atmospheric pressure. The study of precipitation forms a major portion of the subject of the hydrometeorology.

3.1 Runoff

Runoff is one of the important parameter of hydrologic cycle. It is defined as that portion of precipitation which is not absorbed by the deep soil strata but finds its way into the stream after meeting the demands of evapotranspiration, interception, infiltration, surface storage, and surface as well as channel detention. It includes surface runoff received into the channels after precipitation occurs, delayed runoff that enters the stream after passing through the land surface, and other delayed runoff from the temporarily detained pits, depressions, swamps or detained as snow fall. It is thus the flow collected from the drainage basin and appearing at the outlet of the basin. The runoff process is demonstrated in Fig. 3.1 as flow chart. Details of the runoff process are discussed as below.

4.1 Introduction

Precipitation is a major component of hydrological cycle. It occurs because of condensation of water vapour molecules in the atmosphere. When the precipitation falls on the grounds, it undergoes several phases before it appears as runoff in the streams. Certain amount of precipitations is intercepted by the foliage of plants and roofs and other parts of the building and other hydraulic structures. This intercepted water is called as interception loss which is evaporated to the atmosphere. Sometimes the dried surface of the buildings and other structures soak certain amount of precipitation while falling on them which also adds to interception loss. After striking the land masses, certain amount of the precipitated water gets infiltrated into the soil surface which then moves both in lateral as well as in vertical direction. This loss is called as infiltration loss. For the study of groundwater, infiltration loss is not a loss but rather it is a gain in terms of groundwater recharge. However for a surface water hydrologist, it is a loss since it decreases the amount of runoff contributing to the stream or any other water bodies.

5.1 Introduction

A steam can be defined as a flow channel in to which the surface runoff flowing over the land surfaces and base flow/ground flow flowing below the ground surfaces meet. It receives the total flow from a specified basin. Streamflow representing the runoff phase of the hydrologic cycle is the most important basic data for hydrologic studies. Interestingly, stream flow is the only part of the hydrologic cycle that can be measured accurately. Stream flow is a historical data and like rainfall and runoff, it is a stochastic hydrologic variable. It is also called as discharge or rate of flow. Discharge is defined as the volume of water flowing through a cross section in a unit time.

6.1 Introduction

When rainfall strikes a ground surface, some losses like initial and infiltration will occur. After these losses are fulfilled, runoff will begin. The runoff will ultimately reach a stream. The main routes through which runoff flows are (i) overland flow, (ii) interflow and (iii) groundwater flow. Overland flow which is also called as surface flow flows over the land mass and reaches a stream. Overland flow soon reaches a stream and if it occurs in sufficient quantity, it forms an important element in the formation of flood peaks. In small and moderate storms, there may have predominant initial and infiltration losses resulting minimum amount of surface runoff and this is especially true in case of permeable soils. If the soil is impermeable, then there may have reasonable runoff. However, surface runoff is an important factor in streamflow only for heavy or high intensity rainfall.

7.1 Introduction

Flood is an unusually high stage in a river resulted due to high rainfall or snow melt which causes large flow of runoff in it. During flood, the river overflows the banks and inundates the adjoining areas. Flood causes heavy damages to buildings and hydraulic structures besides causing catastrophic loss to human life and property. It causes great economic loss due to disruption of many structures and damage to agricultural fields. Many forest and aquatic lives are affected by the flood. Hundreds of crores of rupees are spent every year to control, forecast and manage the flood.

8.1 Introduction

The knowledge of statistics and probability is very helpful for correct prediction of hydrological data and correct prediction of hydrological data is useful in giving good performance in all water resources projects. Since hydrological data are highly stochastic varying both in space and time, it is essential to predict them as correct as possible. The hydrologic evens do not depend on physical and chemical laws but depend entirely on nature. They cannot be predicted exactly by using any relationship but can be predicted at different probability levels by fitting suitable probability distribution functions. Application of statistics and probability in the field of hydrology can help to predict the hydrologic events in a better way. In hydrology, objectives of statistics are as follows (Suresh, 2008):

9.1 Introduction

Flood water which is in the form of a hydrograph when passes down a river section undergoes several changes in its form. There may be some addition of water to the river section when the flood wave passes down the river section. There may be some diversion of water from the section. Thus, depending on the addition or abstraction of water to the incoming flood water, shape of the flood hydrograph in the downstream section may change. Sometimes channel storage and resistance to flow of water in the channel section also affects the shape of the flood hydrograph.

It is difficult to ascertain which came first, food or human being. It is the same situation as chicken and egg where we lack evidence to indicate which came first on earth.

It does not matter which came first but we know for sure that human being needs food and he or she needs everyday and throughout his or her life. In other words, a human being cannot survive without food indicating permanent unbreakable bondage between food and human being. It supports the basics of human civilization-food, agriculture and humanity.

1.    I deem it a singular honour to deliver Dr. Sen Memorial Lecture. Dr. Sen, who was both an administrator and a visionary, was instrumental for:

SYNOPSIS

Food is an essential element without which human being cannot survive. We need it for our maintenance and growth everyday and through the longevity of our life. As we understand food, it is a bunch of essential elements which is essentially needed for the engine of human body to run non-stop. The understanding of food is much required by masses who consume it every day. The present paper attempts to describe the knowledge on food, feeling on food by consumers, prevailing food, hunger and malnutrition, healthy food and studies required on consumable foods.

SYNOPSIS

We lag in nutritional awareness. The therapeutic values of plant foods, such as vegetables, fruits, grains, legumes, nuts, seeds, herbs, spices and other foods like dairy products, fluids and meats are to be brought to light. The values of important nutrients, may lead to the basis for nutritional education lacking at present. There is need to bring awareness and add to the knowledge of the younger generation. A food is something that provides nutrients. Nutrients are substances that provide: energy for activity, growth, and all functions of the body such as breathing, digesting food, and keeping warm; materials for the growth and repair of the body, and for keeping the immune system healthy.

SYNOPSIS

The availability of food is of paramount importance without which it is hard for human beings to survive. The recognized way of making food available is to produce but it is also equally important that food produced is utilized well without loss of edible food materials. The paper discusses on unused food, under- utilized food within and across countries, and puts emphasis on utilization and handling of food. In perspective, the paper highlights the steps to be taken up to save and utilize the food already produced.

SYNOPSIS

In all probability the ancient farmer’s market originated on the streets of villages and later on, on the streets of towns. The street food survived through decades and centuries and now it has assumed its new role in fulfilling the readymade food demand of the working people of mega cities. The street food has now more relevance to the growing urban population. With the lapse of time and migration people to the cities, the business and activities of street food got expanded in qualitative and quantitative terms worldwide.

SYNOPSIS

With the change of time, and the progressive development in life-style, the menu of food has undergone significant changes in communities, countries, regions and worldwide. This is influenced by the travel, migration of the people, and enhancement of the socio-economic status among the masses.

SYNOPSIS

Nature produces plants with healing properties. Hundreds of phytochemicals and antioxidants have been identified in various food plants. Many plants or plant parts are eaten as food. There are several plant species which are cultivated for food, and many have several distinct cultivars. Seeds of plants are a good source of food for animals, including humans, because they contain the nutrients necessary for the plant’s initial growth, including many healthful fats, such as Omega fats. In fact, the majority of foods consumed by human beings are seed-based foods.

SYNOPSIS

Food is any substance consumed to provide nutritional support for the body. It is usually of plant or animal or fish origin. Plant foods are the most abundant sources of nutrition on earth. Only plants contain powerful substances called phytochemicals, which protect us from cancer, heart disease, and an array of other serious illnesses.

SYNOPSIS

Many plants or plant parts are eaten as food. In addition to essential vitamins, minerals, and fibers, plant foods contain phytochemicals and antioxidants, which actively provide protection against diseases. Several studies carried out all over the world have demonstrated the protective values of fruits. Fruits are the ripened ovaries of plants, including the seeds within. Many plants have evolved fruits that are attractive as a food source to animals, so that animals will eat the fruits and excrete the seeds some distance away.

SYNOPSIS

Animal source foods (ASF) include any food item that comes from an animal source such as meat, milk, fish, eggs, cheese and yogurt. Many individuals do not consume ASF or consume little ASF by either personal choice or necessity as ASF may not be accessible or available to these people. Animals are used as food either directly or indirectly by the products they produce. Animal source foods (ASF) include any food item that comes from an animal source such as meat, milk, fish, eggs, cheese and yogurt.

SYNOPSIS

Fish has now become an important animal protein for mankind. It is a rich source of essential amino acids, vitamins and minerals. Fish meat is easily digestible compared to other animal meat and has a higher Protein Efficiency Ratio when compared to casein, the milk protein. Fish oils like body oils of fishes like sardine, mackeral, anchoviella, herring, salmon etc. are the richest source for Omega-3 long chain poly unsaturate fatty acid like Eicos- pentanoic acid (EPA) and Docosahexaenoic acid (DHA) having therapeutical applications for man. A number of fishery products and by-products like squalene, chitin, chitosan, oyster meat, mussel meat, shark bones etc.

SYNOPSIS

Flavor is the sensory impression of a food or other substance, and is determined mainly by the chemical senses of taste and smell. The flavor of the food, as such, can be altered with natural or artificial flavorings which affect these senses. Smell is the main determinant of a food item’s flavor. While the taste of food is limited to sweet, sour, bitter, salty, umami (savory), pungent or piquant, and metallic – the seven basic tastes – the smells of a food are potentially limitless.

SYNOPSIS

Vegetables are essential for well-balanced diet since they supply phytonutriceuticals. About 3 billion people in the world are malnourished due to imbalanced diets. Regular consumption of a vegetable rich diet has undeniable effects on health since they have been strongly associated with improvement of gastrointestinal health, good vision, and reduced risk of heart disease, stroke, chronic diseases such as diabetes, and some forms of cancer.

SYNOPSIS

There is an increasing awareness about quality of food among consumers all over the world. Organically produced food is considered to be nutritionally superior, but the available information is not conclusive.

SYNOPSIS

There have been conflicting practices, recommendations regarding a healthy diet in human beings. Unscientific food habits are limitation to good health and active life. Because of various social, cultural, religious and economic factors human beings in the same climatic conditions and living situations, have been practicing different food habits leading to many health problems. What to eat, how much to eat and when to eat are not clear with the masses. This paper attempts to throw light on these aspects.

SYNOPSIS

Human health is defined as a state of physical, mental, physiological and social well being. It is also considered as a state of body and mind, where there is a balance of body humors or secretions. The paper introduces the readers to common diseases caused through various agents like deficiency disorders, food and water, air-borne, vector, viruses, and life-styles. It also describes healthy food, health management, food management, and healthy life style.

Note: With my personal experience, I have learnt many lessons during the course of my journey of life. The reader should ponder over it and prepare own food profile and menu for the benefit of maintaining good health. My paper does not provide any prescription but provides illustration of my experiences only, which may be of some use in knowledge and practice of food. The medical and health experts need to be consulted as appropriate.

Synopsis

If the human being was born first, he or she needed food immediately to survive. Thereafter, human beings continued to need food and continued to eat food throughout his or her life. Hence, the relationship between human being and food is permanent and the requirement of food for the human being to be alive is everlasting. The paper provides the background, definition of right to food, and adequate food, historical events, legal perspectives, operational guidelines, and advances in its application and derives conclusion.

SYNOPSIS

Inspite of the fact that governments in various food summits and conferences have made commitments on food and nutrition security, presently more than a billion people are suffering from hunger and malnutrition worldwide. The food and nutrition policies need to be revisited and updated to address both man-made food scarcities and natural disasters of present and future to mitigate hunger and malnutrition.

On different occasions I have expressed my views on hunger and food security. Here are some of the views published earlier.

1. Food Security bill: Why it is an opportunity lost

Several years ago I and Dr M S Swaminathan were speaking at a conference on hunger at Rome. Also speaking at one of the sessions was the Brazilian Minister for Zero Hunger Programme, the dream programme of ex-President LuizInácio Lula da Silva. After he had listened to us, he sat down with us to know of how India was battling hunger, specially the way India was managing its food self-sufficiency and the massive food procurement programme.

SYNOPSIS

Urban and rural agriculture are different entities in terms of stakeholder involvement and enabling environment for farming but they are dialectically interlinked in providing food and nutrition security of any country. Urban agriculture is more suitable on the production of nutritious crops, while rural agriculture’s first priority is to produce more food from staple. Attaining nutrition security is more complex than it is previously thought. However, while existing systems of production should continue at field levels by developing more nutritionally rich cropping patterns, its integration with farmers’ farming systems remains more important.

Synopsis

Food safety has become increasingly important with globalization due to various factors such as increased volume and diversity of trade in foods, greater public demand for health protection, changing hazards e.g., resistant microbes, more sophisticated methods for detection of hazards, changes in production and consumption pattern, etc. Food safety contributes significantly to food security as unsafe and poor quality food leads to illnesses as well as food wastage. This leads to a strong need to emphasize not only on availability of food but also ensure that the same is safe.