eChapters

3.1 Introduction

To remove the inequality in technology development and its use, the concept Gender and technology arises. Economic resources should be equally distributed among the men and women. Technology can also help challenge and break gender stereotypes and biases that often limit women's potential. First of all, much equipment tends to be gender-typed. There are machines and tools suitable" for men as saws, trucks, wrenches, guns and forklifts. Some other technologies are "suitable" for women as vacuum cleaners, typewriters and food processors. The main focus of year 2023 is on innovation and technology for gender equality. Innovation and technological change are deep shifts reshaping life in the twenty-first century. Technological progress allows for unprecedented advances with the potential to improve social, economic and political outcomes for all.

 

2.1 Gender Analysis

Inequalities between men and women are becoming more visible and glaring particularly in developing countries of the world triggering serious concern over developed experts. UNESCO statistics reveals that women perform 75 per cent of work, earn 10 per cent of the income and own 1 per cent of property. The 3rd UN Millennium Development Goal (MDG) has called for gender equality and the components of women to battle poverty, hunger and disease and to restorative development that is precisely sustainable.

The Beijing Platform for Action (1995) very well support this fact in form of twelve objectives and action points viz., women and poverty, education and training for women, women and health, violence against women and armed conflicts, women and the economy, women in power and decision making, institutional mechanism for the development of women, human rights of women, women and media, women and environment, and the girl child. Prior to the above declaration there were First, Second and Third World Conference on Women at Mexico (1975), Copenhagen (1980) and Nairobi (1985), respectively.

1.1 Introduction

Gender permeates every facet of society, influencing power dynamics, access to resources, and opportunities. Understanding gender requires not only defining its conceptual framework but also acknowledging how these concepts manifest in everyday life, often creating deep divisions. Gender divides whether in education, employment, health, or political participation are enduring realities that reflect the unequal distribution of opportunities and rights between men and women, as well as between those who identify beyond the binary. These divides are more than social phenomena; they have concrete economic, political, and developmental impacts. Recognizing the persistent gaps in access and outcomes between genders has led to the development of gender-sensitive policies, such as gender budgeting. Gender budgeting is a critical tool for addressing these divides by ensuring that public resources are allocated equitably to benefit all genders. By focusing on the differential impacts of policies and budgets on women, men, and gender minorities, governments and organizations can work toward creating more inclusive and fair societies.

This chapter will introduce key gender-related concepts that form the foundation for understanding how gender influences social, economic, and political life. It will explore the roots and ramifications of gender divides across various sectors and explain how gender budgeting is employed as a strategic approach to reduce these disparities. Through this exploration, we will highlight the importance of integrating gender perspectives into policy and resource distribution to foster equity and social justice.

2.1Introduction

Agriculture includes both self-employment and wage employment. This require precise information about who does what. Majority of farmers have small Land holding and landless labourers. This needs understanding of activity performance of men and women. Gender-based division of labour is universal, but culture and community diversities cause differentiation. Gender, therefore, has to be recognized as the social characteristic that cuts across caste, class, occupation, age and ethnicity. It is gender that differentiates the roles, responsibilities, resources, constraints and opportunities of women and men in agriculture for which precise gender information is the need of the day. Building gender into agricultural development will lead to: Building inherent strength of women and men to mutually learn, Overcoming gender based prejudices etc.

2.2

Importance of Gender in Agriculture Agriculture play an important role in livelihoods of the rural poor and achievement of the Millennium Development Goals (MDGs). Agriculture can be the engine of growth and is necessary to reduce poverty and food insecurity. The changes in Agriculture sector generate new sources of opportunities for livelihoods and food security, they also pose significant qualms. Equity distresses are being raised.

The concept of gender, distinct from biological sex, serves as a lens through which societies organize individuals and define roles, expectations, and relationships. Gender is not merely a matter of identity but an intersectional construct shaped by cultural, social, economic, and political influences. It reflects how different societies understand and express masculinity, femininity, and other gender identities, often dictating the power dynamics, opportunities, and constraints placed on individuals.

The understanding of gender has evolved significantly over time. Initially, it was viewed as a binary construct aligned strictly with biological sex; however, modern perspectives recognize gender as a fluid and dynamic concept, shaped by individual experiences, social interactions, and institutional norms. This evolution has brought about greater recognition of diverse gender identities, challenging traditional binaries and expanding the conversation to include non-binary, transgender, and gender non-conforming identities.

At the heart of gender are the societal structures that enforce roles and expectations. These structures differ across cultures and historical periods but commonly emphasize the division of labor, power, and resources between men and women. Gender not only influences individual identity but also informs how societies function, shaping everything from economic participation to political representation.

Introduction

Impact assessment (IA) is defined as "a set of logical steps to be followed in the preparation of policy proposals. It is an essential tool to ensure that policies are crafted based on transparent, inclusive, and balanced procedures, define the various quality standards, and provide basic instructions to the impact assessment process" (European Commission).

The practice of official release of cultivars in India started in October, 1964 with the formation of the Central Variety Release Committee (CVRC) at the Central government level and State Variety Release Committee at State Government level. The Central Variety Release Committee functioned up to 1969 when its functions were taken over by the Central Seed Committee (CSC) established under the Seeds Act, 1966. The Central Seed Committee later on bifurcated CVRC and constituted (i) a Central Sub-Committee on Crop Standards Notification and Release of Varieties for Agricultural Crops and (ii) a Central Sub-Committee on Crop Standards Notification and Release of Varieties for Horticultural Crops to discharge the functions of release/notification, provisional notification and de-notification of cultivars at Central level for field and horticultural crops respectively. State Seed Sub-Committees (SSSC) were asked to discharge similar functions for release at State level. Central Sub-Committee on Crop Standards, Notification and Release of Varieties for Agricultural Crops is responsible for release and notification of field crops. This committee is chaired by ICAR-Deputy Director General (Crop Science). The members are drawn from Directors/Crop Coordinators of ICAR, Directors Agriculture from States, Directors Seed Certification Agencies, Managing Directors of State Seed Corporations, Representatives from Private Seed Companies, etc. 

Pure-breeding

Mating purebred individuals of the same breed. The progeny share the same genetic make-up. The primary goal of pure-breeding is to identify and propagate superior genes for use in commercial production, primarily through crossbreeding programmes, as well as to identify and propagate better females for the preservation of precious genetic material. Therefore, crossbreeding will be futile unless superior purebred individuals are used.

Introduction Pulses are a vital source of protein (20-25%) in comparison to cereal proteins (10-12%); which cater to the most vegetarian population (Venkidasamy et al., 2019) and other countries which are scarcity of animal protein availability. In the category of pulse crop, chickpea is considered the second utmost significant crop, which is grown in almost 35 countries globally. Chickpea mainly contains carbohydrates, protein, minerals, vitamins, dietary fiber, folate, β-carotene and health-promoting fatty acids (Badshah et al., 2003; Tosh & Yada, 2010) and consuming these grains will repeatedly help in lowering the risk of chronic diseases (Jukanti, Gaur, Gowda, & Chibbar, 2012). Ozone is often regarded as a potent oxidant capable of penetrating the grain (Tiwari et al., 2010), and it can control the bio-agents such as insects, molds, and mycotoxins (Wang et al., 2016). Due to the fact that ozone gas is unstable, it convert back into oxygen without leaving any residues in short time (McClurkin, & Maier, 2010), so, it can be used as a fumigant without leaving any residue. The Food and Drug Administration (FAO) has approved it for fumigating grains, fruits, and vegetables.

4H: An agricultural club for children that features hands-on learning

Abiota: The nonliving component of an ecosystem, including the soil, water,

and air.

Aborigines: The original or native inhabitants of a country or region.

Absorption Losses: Loss of water from a canal or a reservoir by capillary

action and percolation and in case of canal during the process of delivery.

Absorptive capacity: The maximum amount of waste that can be absorbed

by the environment.

Acclimation: Adaptation to changing or new conditions.

Acid precipitation: Rain, snow, fog, or dew containing sulfuric and nitric acids

produced by fossil fuel combustion.

Acid soil: A soil which is deficient in available bases, particularly Ca and which

give an acid reaction when tested by a standard method.

Acre foot water: The amount of water that would cover an area of land to a

depth of one foot assuming no seepage evaporation and run off.

Acre inch day: Term used principally in irrigated section of united state for

measuring quantity of flow of water. It is equal to a flow which will cover

one acre to a depth of one inch in a 24 hours period or 0.042 cubic feet per

second.

Acre inch: It is a measure of quantity of flow of water and is equal to the flow

which will cover one acre to a depth of one inch.

Acre: (43560 sq. ft) an area of land about 220 feet long and 198 feet wide.

Active solar heating: The use of solar panels to collect and concentrate the

sun’s energy for heating.

Adaptation: Biological modification that allows species to better exist in a

specific environment.

Additives: Chemicals added to food, often con- sidered to represent a threat

to human health.

15.1 Agricultural Economics and Definition

As a separate subject, agricultural economics emerged in the beginning of 20th century when the economic issues related to agriculture aroused interest at various educational centres. The depression of 1890s which wrecked have in agriculture at many places and it forced organised farmers groups to take keen interest in farm management problems. The study and teaching of agricultural economics was started at Harvard University (U.S.A.) in 1903 by Professor Thomas Nixon Carver. Agricultural economics may be defined as the “Application of Principles & Methods of economics to study the problems of agriculture to get maximum output and profits from the use of minimum in but for the wellness of society in general as well as the farming industry in Particular.

A

Adenocarcinomas 3, 7

Adenomas 7

ALDH1 17, 18

Anaplastic carcinomas 7

B

Babesiosis 1

Bcl 17, 21, 23

Benign tumors 3, 5

Biomarkers 17, , 29, 30, 31

BRCA 31

C

Canine 1, 2, 5, 7, 8, 9, 10, 11, 12, 13, 17, 19,

19, 22, 23, 24, 27, 29, 30, 32, 33, 34

Canine distemper 1

Canine Mammary Tumors 1, , 5, 7, 8, 13, 17,

19, 29, 32, 33

Canine parvoviral diarrhoea 1

Carcinogenesis 10, 25

CHEK2 15

Classification and Grading 7

Companion animals 1, 9

COX inhibitors 21, 26

Cyclooxygenases 23, 26, 35

D

Deracoxib 21, 26

Diagnosis 19, 20

Doxorubicin 21

E

EMT 17, 25

Epidemiology 11

Estrogen receptors 20

FGFR2 15

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(2012). Circulating cell-free DNA: a promising marker of regional lymphnode metastasis

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Badowska-Kozakiewicz A. M., and Malicka E. (2012). Immunohistochemical evaluation of

expression of heat shock proteins HSP70 and HSP90 in mammary gland neoplasms in

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(2017). Circulating cell-free DNA in dogs with mammary tumors: short and long fragments

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Birdi R., Kumar B. S., Gupta K., Kashyap N., & KumarA. (2019). Circulating level of heat

shock protein 27 is elevated in dogs with mammary tumors. 3 Biotech 9 (6), 1-9.

Campos L. C., Lavalle G. E., Estrela-Lima A., Melgaço de Faria J. C., Guimaraes J. E., DutraA.

P. and Cassali G. D. (2012). CA 15.3, CEA and LDH in dogs with malignant mammary

tumors. Journal of Veterinary Internal Medicine, 26 (6), 1383-88.

Mammary tumors are the most common type of neoplasia found in female dogs with high percentage of malignancy and rate of mortality. The rate of incidence of these mammary neoplasia and dysplasia is continuously advancing nationally and internationally over the last 45 years. There are different risk factors such as age, diet, hormonal exposure and breeds, which are required to be monitored in order to control the incidence of CMTs. In addition to conventional therapies such as surgical excision, radiotherapy and chemotherapy, additional precision therapeutic agents targeting TKIs, p53 tumor suppressor gene, cyclooxygenases, epithelial-mesenchymal transitions and various hormones/ hormonal receptors could be beneficial for the treatment of CMTs. Scientific efforts are also being made to develop different biomarker panels and tests for prognosis/diagnosis of the diseases as well as to develop vaccines against CMTs.

In GADVASU, under the DBT sponsored project on “Development and evaluation of serodiagnostic assay for timely diagnosis and prognosis of mammary tumors”, we have generated and used hyper-immune sera raised against certain canine recombinant mammary tumor associated proteins for the standardization of sandwich and indirect ELISA for serodiagnosis of canine mammary tumor. The sensitivity and specificities of the assay’s ranges between 85-88% and 80-85%, respectively. However, an antibody against a single marker when used for different histotypes of CMT, its specificity reduced significantly. Multiplex assays are capable to detect many specific antigens in a single run whereas a traditional ELISA is used only to detect a single antigen. It has high-throughput potential, providing more results per sample, with lower sample volumes and with utmost sensitivity and specificity. Attempts are being made to increase the sensitivity and specificities of the assays by multiplexing various markers together (Fig.4).

Although there have been multiple biomarkers for mammary tumors both in human and canines reported over the time (Table 3), but no absolute biomarker for diagnosis and prognosis of CMT has been found yet. Out of several studies on clinical applications of different mammary tumor biomarkers, some showed a particular promising biomarker, on the other hand controversial results also existed for the same. For example, HER-2, which is one of the most prominent bio-marker both in HBC and CMT. HER-2 overexpression is associated with poor prognosis and reduced overall survival of the subject, but there are studies available which suggest no difference in HER-2 expression between benign and malignant tumors and studies showing HER-2 expression suggesting prolonged survival (Kaszak et al., 2018). Various biomarkers of mammary tumors are not mammary tumor specific such as p53, COX-2, PCNA etc. These markers undergo alterations in their expression level in all tumors. By keeping this in mind we need to device a panel of different markers to ensure the correct prognosis and diagnosis of canine mammary tumors. There are limited studies and only few commercial kits (for human) available using such combinations (Table 4).

One of the most promising areas of veterinary research these days is cancer immunotherapy and the development of CMT vaccines. DNA vaccines, also known as gene vaccines, are designed to transfer functional genes to target cells, allowing them to express functional proteins. Because endonucleases may easily access bare DNA, it requires a reliable and safe delivery route, which might be biological or non-biological. Different delivery strategies have been tried in human breast tumors to transport tumor antigens such Mucin-1 (MUC-1), Twist, HER-2, mammaglobin-1 and p53, as well as immunostimulatory molecules like IL-12 and IL-6. There have been various studies/ trials in canine animals using different molecules like IL-12, HER-2 and IFN-γ as vaccine candidates, with no clinically relevant outcomes or longlasting cell mediated and humoral immune response outcomes

In addition to the conventional treatment methods i.e., surgery, chemotherapy and radiotherapy, there are some adjuvant targeted therapies which block the growth of cancer by altering the individually expressed specific molecules responsible for tumor cell proliferation, survival, metastasis or microenvironment. The majorly studied adjuvant therapies include use of hormones, tyrosine kinase receptors, anti-cyclooxygenases, anti-tumor suppressor gene p53 and epithelial-mesenchymal transition inhibition.

The main aim of hormonal therapy (Table 2) is to inhibit the hormone induced stimulation of carcinoma cells, which could be achieved either by ovariohysterectomy or different treatments like use of specific estrogen receptor modulators (SERMS), aromatase inhibitors for suppression of estrogen synthesis etc. A commonly used estrogen receptor (ER) antagonist drug tamoxifen for treatment of ER positive breast cancer in women, has also been tested against CMTs. However, it is not a viable treatment option in dogs due to associated side effects. Ovariohysterectomy is considered as a better and practical solution. The use of hormonal therapy in CMTs is based on the evidence of hormone dependency of these tumors as well as lessons learnt from hormonal therapy outcomes from human breast cancer. This therapy significantly ameliorates the recurrence of breast cancers and prolongs the survival rates in women having breast cancers positive for hormone receptors. However, the results of the canine investigations, which are all retrospective and non-randomized, are contradictory. Detailed research and prospective randomized trials, where effect of OHE is studied in context of hormone receptor status, are required to determine the role of hormonal therapy in CMTs.

Surgical removal is the routine treatment method for mammary tumors, however, there is no consensus on the optimal procedure. There are supporting factors for every surgical procedure conducted for mammary tumors including lumpectomy (removal of tumor only), mastectomy (affected gland removal only), radical mastectomy (complete mammary gland and associated lymphatic tissue removal) and modified radical mastectomy (removal of complete mammary gland, lymph nodes and associated chest muscles).The more extensive procedures do not increase survival in dogs when compared to the other procedures, and the benefits of the simpler procedures are clear. Further, the radical mastectomy increases the disease-free interval but not the survival duration in cats.