eChapters

Nephrology

Nephritis and renal calculi are the two major problems leading to renal failure in canine and feline nephrology. Chronic renal failure may occur at any age but it is more common in geriatric dogs. Congenital renal diseases may also lead to renal failure at any age. Chronic renal disease or chronic renal failure is a progressive deteriorating condition as compensatory mechanism (glomerular hypertension and hyper filtration) further deteriorate the condition. Hence chronic renal disease remains lifelong. For quality life, an early diagnosis of renal failure is very important. The following techniques are used to diagnose chronic renal failure.

Introduction

The classic bone tissue engineering paradigm highlights several key players: biocompatible scaffold that closely mimics the natural bone extracellular matrix niche, osteogenic cells to lay down the bone tissue matrix, morphogenic signals that help to direct the cells to the phenotypically desirable type, and sufficient vascularization to meet the growing tissue nutrient supply and clearance needs. The biomaterials are critical components in the bone-tissue engineering strategies, including polymers, ceramics, or their combinations applied in various forms, such as membranes and three-dimensional (3D) scaffolds. These materials typically mimic the extracellular matrix of bone tissue during the tissue regeneration process, providing mechanical support and a suitable environment for cell attachment, proliferation, and differentiation

Abstract
Digital transformation in agriculture represents a profound shift towards integrating digital technologies into farming practices to enhance productivity, sustainability, and efficiency. This chapter explores the
multifaceted aspects of digital transformation in agriculture, including theb role of technologies such as the Internet of Things (IoT), artificial intelligence (AI), big data analytics, and block chain. It examines how these technologies are reshaping agricultural practices, improving decision-making, and addressing challenges related to resource management, crop monitoring, and supply chain optimization. The chapter also discusses the implications of digital transformation for stakeholders, including farmers, policymakers, and technology providers, and offers recommendations for leveraging digital tools to advance sustainable agricultural practices and ensure food security in the digital age.
Keywords: Digital transformation, agriculture, Internet of Things (IoT), artificial intelligence (AI), big data analytics, block chain, precision farming, smart agriculture, supply chain optimization, resource management.

Introduction
A microorganism or microbe is a tiny living thing that can exist as a single cell or in groups of cells. People have suspected the existence of these unseen microbes since ancient times. These single-celled creatures have caused serious infections that often led to deaths and illness. These microorganisms can spread quickly and cause big outbreaks of disease. In 1928, Alexander Fleming discovered the first antibiotic, penicillin. This discovery started the development of one of the most important groups of medicines in medical history. In the next three decades, many different types of antimicrobial drugs were developed. In his Nobel Prize speech, Fleming warned that using penicillin too much might one day lead to bacteria becoming resistant to it, which would be a major problem. Antimicrobial resistance (AMR) is one of the biggest public health challenges today. Many of the microbes that cause diseases, like bacteria, viruses, and protozoa, no longer respond to common antimicrobial drugs such as antibiotics, antivirals, and antiprotozoals. Antimicrobial resistance is when a microbe becomes able to survive and grow even when treated with medications that used to work on it. Antibiotic resistance is a type of AMR, but it only applies to bacteria becoming resistant to antibiotics. Resistant microbes are harder to treat, and doctors may need to use other medicines or higher doses. These options can be more expensive and have more side effects. Microbes that resist multiple antimicrobials are called multidrug resistant (MDR). Those that are resistant to almost all drugs are sometimes called ‘superbugs’. Antimicrobial prophylaxis is used by doctors to prevent infections, but it should only be used when it’s really needed to avoid unnecessary costs, side effects, and the development of resistance. Antimicrobial prophylaxis can be used to prevent a first infection or to stop an infection from coming back or reactivating.

Entrepreneurship Development
Entrepreneurship Development (ED) is a recent perspective in extension approaches. It attempts to integrate sociological nature of agricultural sector with capitalistic entrepreneurship. The terms like social entrepreneurship, corporate social responsibility and agricultural entrepreneurship have recently come in vogue. It is the most significant factor to bring about transformation of agricultural sector.
Theories of Entrepreneurship Development
The word entrepreneur is derived from a French root entreprenerd, meaning. to begin something, to undertake. Entrepreneur is a person with a high need for achievement [N-Ach] who is energetic and a moderate risk taker. An entrepreneur searches for change, responds to it and exploits opportunities. Entrepreneur is an innovator and dynamic agent of change, a catalyst who transforms increasingly physical, natural and human resources in a corresponding production possibility. Entrepreneurship is a means by which economy and society are transformed. The emergence of entrepreneurs in a society depends upon closely interlinked economic, social, religious, cultural and psychological variables.
Personality traits perspective of entrepreneurship
In this approach, the entrepreneur is assumed to possess a particular personality type and thus much research has been to enumerate a set of characteristics possessed. The main Concepts studied include innovativeness, dynamism, risk taking, creativity, alertness, need for achievement, aspirations, self-confidence and being ambitious. An entrepreneur is an individual who possesses qualities of risk-taking, leadership, motivation, and the ability to resolve problems. Entrepreneurial attitudes and behaviour also include openness to new information and people, motivation, making independent and self-directed decisions, the ability to see opportunities in a rapidly changing and uncertain environment, persistence, the motivation to achieve, technical know-how, taking ownership, personal integrity, accountable, capacity to manage and
organise.

To a layman, wasteland is a piece of land, which is lying uninhabited or uncultivated. These lands are also commonly perceived to produce much less than their potential. Depleted of the green cover and productivity, such lands are often in a critical condition. Broadly, wastelands may be defined as land where the production of biomass is less than its optimum ‘productivity. Wasteland also refers to lands, which are economically unproductive, ecologically unstable and subject to environmental deterioration.

What is Computer Network?

A computer network is a collection of computers and devices connected to each other. The network allows computers to communicate with each other and share resources and information. The Advance Research Projects Agency (ARPA) designed “Advanced Research Projects Agency Network” (ARPANET) for the United States Department of Defence. It was the first computer network in the world in late 1960’s and early 1970’s

Health care is an important way of making sure that rabbits stay productive. Every rabbit keeper should know how to recognize and, if possible, prevent and cure illnesses which can affect rabbits.

It is always better to prevent disease incidence than to let animals get ill and then try to treat them. Allowing rabbits to get sick is expensive for several reasons, sick animals stops growing and reproducing so money is lost with this decrease in production, some disease results in the death of rabbits, replacing the dead rabbits is expensive , treatment for the ill rabbits is usually expensive.

Mutations are sudden and heritable changes in the genetic material. They can result in deletion, inversion and translocation of certain portions in the chromosomes, which can result in the changed expression of a trait due to the interaction of alleles within or without the locus, sometimes the effects revert back or can be heritable.

Most of the fruit crops are highly heterozygous. However, heterozygosity is one of the advantages when it comes to mutation. In highly heterozygous crops wherein there is a need for improvement in a single trait, mutations have been of great use. One of main limitations is use of vegetative material, which due to the unlikelyhood of uniform penetration and distribution of mutagenic agent can result in chimera. Although hybridization and selection have made a fair dent in the improvement of fruit crops, mutation is one of the methods that can be relied upon to develop pre-breeding lines and to bring about change in the quantitavie traits. Another very important fact is that there are crops like grapes wherein a lot of spontaneous mutants have become established varieties viz., Sonaka and Saritha to quote a few. Some of the existing varieites wherein one or two traits need to be improved, mutation would greatly help in this in comparatively short time. In some of the crops like sapota, wherein the conventional breeding would take long time, mutation can be resorted to both for inducing variability in the germplasm as well as for trait improvement. It is also to be noted here that mutation breeding can be a good supplement for conventional breeding, more so with the emergence of tissue culture propagation, which often throws up spontaneous mutants. Mutation as a methodology can also be tried in some fruit crop spp where there is no disease resistance source within. It can also be adopted in cases where there is a need to break linkages.

SOIL WATER

Soil water and oxygen share the pore space in soil and generally the oxygen content is determined by the water content, which is added by irrigation or rains and then keeps on changing due to evapotranspiration. Water is the vehicle by which most nutrients move from the soil to root surface. But for the lowland rice, nutrients are most available to plants at ?eld capacity moisture (about 0.3 atmosphere soil water tension) and the availability decreases as the moisture content decreases to wilting point (about 15 atmosphere tension). That is why rainwater or irrigation increases nutrient availability, while extremely dry condition decreases it. There is thus a signi?cant interaction between water and nutrient availability in soil (Singh et al., 2014). In a study in India (Singh et al., 1980) the yield of wheat was signi?cantly affected by irrigation water and nitrogen treatments; maximum yield was obtained with irrigation at 50% available soil water in 60 cm soil depth and 120 kg ha ^–1 nitrogen addition. A study on wheat at Delhi (Kumar et al., 2015) very well shows the effect of irrigation water on yield and uptake of nutrients (NPK) (Table 5.1).

In agro-ecosystem, many agricultural and horticultural crops are dependent on insects for their pollination; their degree of interdependence varies species to species. Some plant species depend primarily on a single pollinator’s species or genus, whereas some plant species accept diverse pollinators. About to 80 per cent of flowering plants’ pollination determined for pollinators (FA0, 2007) and out of that most of the floras depend on insect pollinators for pollination and pollinators depend on flora for their food. Bees are considered as most important pollinator due to their diversity, credential ability and effective pollinators of many plant species. Most of the crops pollination need was met by wild pollinators living within the farming landscape (Kevan and Phillips, 2001). Therefore, pollinators play paramount role in ecosystem through enhance the crop productivity and conserving biodiversity. On the above service of pollinators is priceless and natural endowment, but the society we live in, always categorized and measured in terms of financial value. In 2005, globally, insect pollination services economic value was estimated to be about €153 billion (Gallai et al., 2009). The United Nations also reported that the economics of ecosystems and biodiversity by insect pollination was valued at £134 billion. The assisted pollination may have to be done when natural pollination is insufficient in order to reduce potential yield loss (Klein et al., 2007).

Principal Scientist and I/c Head, Division of Social Sciences and Training, IIHR, Hessaraghatta Lake Post, Bangalore – 560 089, Karnataka

Business analytics focuses on data, statistical analysis and reporting to help investigate and analyze business performance, provide insights, and drive recommendations to improve performance.

What are the 4 types of business analytics?

Introduction

India was a self-sufficient nation in its food production before independence but after the occurrence of various famines, the government in late 1960s started focusing more on the crop production i.e.,green revolution (NAAS 2019). Use of hybrids, fertilizers and plant protection chemicals increased and major investments were made on irrigation structures which led to a massive jump in the production of crops. But with time, the negative externalities caused by green revolution were vividly noticeable. The indiscriminate use of chemicals has debilitated the environment by causing soil depletion, pollution, deforestation, climate change etc. thus affecting the health of human kind. The lofty prices of inputs led the farmers to resort to debt thus falling into debt trap and suicides. In order to address this problem an alternative to the conventional farming is required which is more sustainable and climate resilient. In the mid-1990s, natural farming viz., Zero Budget Natural Farming (ZBNF) was demonstrated by Sh. Subhash Palekar also known Subash Palekar Natural Farming (SPNF). It is an agroecology based diversified farming system which involves no financial outlay to purchase essential from outside and makes farming profitable. Mishra (2018) studied on Zero Budget Natural Farming (ZBNF) and found that crops grown under ZBNF evinced higher yield than the crops grown under non-ZBNF.

Abstract
Economic and policy considerations play a crucial role in shaping the landscape of modern agriculture. As the sector faces increasing pressures from global population growth, climate change, and resource constraints, understanding the economic dynamics and developing effective policies are essential for fostering sustainable agricultural practices. This chapter explores the economic factors influencing agriculture, including market dynamics, financial viability, and investment strategies. It also examines key policy considerations, such as regulatory frameworks, subsidies, and international trade agreements. By analyzing these aspects, the chapter aims to provide a comprehensive overview of how economic and policy considerations impact agricultural development and sustainability. It offers recommendations for policymakers, stakeholders, and industry leaders to create a more resilient and equitable agricultural sector.
Keywords: Economic considerations, policy frameworks, agriculture, market dynamics, financial viability, investment strategies, subsidies, international trade agreements, regulatory frameworks, sustainable agriculture.

Introduction
Antimicrobial resistance (AMR) is an escalating global concern, rendering many once-effective antimicrobials useless and threatening modern medicine’s foundations [1]. RNA-based therapies offer precision, programmability, and modularity—tailoring interventions directly to microbial genetic machinery [2, 3].
Main RNA-based modalities include
• Antisense Oligonucleotides (ASOs): Short synthetic single-stranded RNAs that bind complementary mRNA in bacteria to inhibit translation or induce RNase H–mediated degradation [15].
• RNA Interference (RNAi): Though classically applied to eukaryotes, siRNAs or crRNAs delivered via nanoparticles (also termed “nanoantibiotics”) can silence microbial resistance or virulence genes while the carrier materials physically damage microbial membranes— enhancing lethality [3, 4,5].
• CRISPR-Cas Systems: Adapted as antimicrobials, CRISPR-Cas tools can precisely target and cleave resistance genes in pathogens via conjugative plasmids or phages [6].
• Ribozymes / External Guide Sequences (EGSs): Engineered noncoding RNAs that harness RNase P or ribozyme activity to degrade specific bacterial mRNAs [16].
Key strengths
• Target specificity—can silence essential microbial or resistance genes while sparing beneficial microbiota.
• Rapid design and adaptability—once delivery systems are in place, targeting new genes requires sequence change alone.
• Synergy potential—combining gene silencing with antibiotics or physical antimicrobial actions increases efficacy.

Similarity between an entrepreneur and a self-employed person is that they both own a business, but self-employment means working for oneself as an independent owner of the business rather than being employed. Majority of business owners fall under the category of self-employed. They begin with a skill or particular set of skills and find that the opportunity to make money arises.
An entrepreneur is a self-employed person having additional attributes of undertaking challenges and moderate risk-taking behaviour to achieve his/her goals. Entrepreneur is a person who organizes and operates a business taking on extraordinary financial risks in order to do so and has a growth orientation. Entrepreneurship is all about risks and rewards. Entrepreneurs think outside the box for the best ways to succeed and move on to their next venture. While the businesses might be of interest it is really the passion of the start-up and leading something to success that drives them every day. Often this can lead to selling the business or moving on to start a new one, once they have everything in place as they are always looking for challenges.
Income generation refers to activities undertaken for monetary returns and livelihood. Income generation is common to entrepreneurship, self-employment and income generation. Activities done for sustenance or low profit activities with minimal challenges are termed as income generation.
Phases of entrepreneurship development
There are three stages of establishing an enterprise:
1. Income generation: In the initial stage one tries to generate surplus or profit. This is done on part time or casual basis to supplement income e.g. a man with some surplus money might put his money in a fixed deposit account in a bank or a chit fund to earn some interest.
2. Self-employment: In the second stage an individual’s fulltime involvement is in his Bown occupation, e.g. a person who starts a general merchant or a grocery shop and s/he remains satisfied with it.

Pseudostem borer: Odoiporus longicollis: Curculionidae

Distribution : It is widely distributed in all banana growing areas and has got introduced into South India somewhere in the eighties and spread fast in the banana areas of Tamil Nadu, Maharashtra, Kerala and Karnataka.

Biology : Adults of the weevil are reddish brown to black and resemble the adults of the rhizome weevil in size and shape. They live for about four months. The snout is long with the characteristic geniculate antennae.

Introduction

The capabilities and effort to collect the geographic data has increased dramatically in the last decade to cope up with the increasing demand for the support of decision making and planning process in the state, national and global level.  From the Government sector, there is a need for spatial data to make quick responses to natural disasters, industrial accidents and environmental crises as actions will be decided based on geography. There is constant pressure to make wise decisions in a more time and cost effective and efficient manner. Accurate and current geospatial data are critical to these decisions.

The quantitative increase in plant body such as increase in the length of stem and root, the number of leaves etc., is referred to as plant growth whereas, the qualitative changes such as germination of seed, formation of leaves, flowers and fruits, falling of leaves and fruits is referred as development. Utilization of these substances for proper development of the plant is regulated by certain chemical messengers called plant growth substances or plant growth regulators, which in minute amounts increase or decrease or modifies the physiological process in plants. Plant growth substances are the chemical other than nutrient which required in very small amount but without which plant can not complete their physiology.

The two sets of internal factors, viz., nutrition and hormone control the growth and development of the plant. The raw material required for growth is supplied by nutritional factors which include the minerals, organic substances the protein, carbohydrates, etc.