eChapters

22.1  Introduction

Plant pests have been part of man’s environment for a long time. Traditional agriculture, which included diverse crops and indigenous crop management practices, provided little opportunity for pests to build up and spread rapidly (Smith and Allen, 1954). Crop production is constantly threatened by increasing difficulties in controlling insect pests, which are a major impediment to improved livelihoods of poor farmers. However, in the quest to increase food production for the growing population, use of pesticides became a norm in crop management. Pesticides became an integral part of the process owing to losses from weeds, diseases and pests reducing the harvestable produce. Use of pesticides along with high yielding varieties, irrigation and improved seed did result in increased productivity. But the rampant use of these chemicals, under the adage, ‘if little is good, a lot more will be better’ has played havoc with human and other life forms.

21.1 Introduction

Plants and insects share a wonderful relationship. Both are dependent on each other at different levels and chemicals emitted by plants connect them to a large extent.  “Plants” contribute to a major share of occupancy on earth and makes several organisms such as insects & microbes and also humans to depend on them for their survival. This dependency leading to several interesting interactions between plants & insects which are often utilized by humans for their own benefit. Plants maintain incredible communication with their associated organisms. Since plants are rich banks of chemicals and constantly emit them in to its immediate environment which contributes in communication between insects and plants. Insects are the major organisms that have a long relation with the plants and there are several incredible ways how plants can interact with insect species.

Chemical ecology is the study of ecological interactions between organisms mediated by chemical produced by those organisms. In short it is considered as the ecological functions of the chemicals. An insect, in various stages of its life history, performs various activities like host plant location, host plant selection,  feeding and oviposition, mating, escape from its natural enemies etc. and the chemicals play a crucial role than visual and audio signals. Chemical ecology encompasses the studies of these chemicals based interactions.

19.1. Introduction

A wave of research on insect pheromones has been initiated in early 1960’s in response to public concern and alarm about chemical pesticides to develop an elegant and ecologically safe technology for the control of insect pests. Pheromones, a class of semiochemicals are considered as ‘Biochemical Pesticides’, belong to the subdivision of Biorational pesticides which include “Microbials” (Viruses, Bacteria, Pathogens etc.) and “Biochemicals” (insect plant growth regulators, semiochemicals etc.). The term biorational (biological + rational) pesticides can be defined as the use of specific and selective chemicals, often with a unique modes of action, that are compatible with natural enemies and the environment, with minimal effect on non-target organisms. Biorational control is based on a diversity of chemical, biological and physical approaches for controlling insect pests which results in minimum risk to man and the environment (Horowitz  et al., 2009).

Plantation crops are high-value commercial crops of greater economic importance which play a pivotal role in the world economy. These include coconut, arecanut, tea, coffee, rubber, cocoa, oil palm, cashew. In this chapter only Cashew and Rubber are dealt with since the other plantation crops have been dealt in the earlier chapters.

17.1 Introduction

Cotton is a major fibre crop of global importance and has high commercial value. It is grown commercially in the temperate and tropical regions of more than 100 countries. Specific areas of production include countries such as China, USA, India, Pakistan, Uzbekistan, Turkey, Australia, Greece, Brazil, Egypt etc., where climatic conditions suit the natural growth requirements of cotton. These include periods of hot and dry weather and adequate moisture obtained through irrigation. Cotton crop is considered as one of the most important cash crops that influenced the industrial and agricultural economy of the different cotton growing countries of world. Thus, cotton is an immensely important crop for the sustainable economy of these countries and livelihood of the farming community. Cotton crop is considered as one of the most important cash crops that influenced the industrial and agricultural economy of the different cotton growing countries of world. Cotton cultivation and textile industry provide livelihood to million persons, therefore any failure of cotton crop significantly influence the economic growth of cotton belt and textile sector.

16.1 Introduction
According to Howard (2001) the major world crop palms are coconut palm (Cocos nucifera L), African oil palm (Elaeis guineensis Jacq.) and date palms (Phoenix dactylifera L). Many other palm species provide products for international commerce and also grown as ornamentals. Some palm species are of local or regional importance and have great potential for expanded development and distribution. In general, commercial production of palms regularly starts on or near natural habitats with little agricultural development.

15.1 Introduction

In recent years, the role of plant secondary metabolites as protective constituents in the human diet has been a growing area of research. Unlike the traditional vitamins, they are not essential for short-term wellbeing, but there is increasing evidence that modest long-term intakes can have favourable impacts on the human health. Teas, coffee and cocoa represent plantation cash crops grown in many of the warmer, less developed regions of the world. They serve as stimulant beverages and their demand is ever increasing day by daily. However, production of these beverages is under the severe threat due to attack from various pests and diseases which cause considerable damage.

14.1 Introduction

Sugarcane, basically a tropical crop in nature, requires a suitable high temperature, a lot of sunshine and rainfall ranging from 1250-2500 mm for its growth and yield. Relatively speaking, it is an intensive user of water as compared to rice and other crops. The total water requirement to mature the crop is about 64-80 acre inches.  Although globally but Brazil and Mexicos in Americas, India, Pakistan, Thailand and China in Asias, Australia and Africa, the Caribbean and to a smaller degree in southern Europe and the Middle East are major sugarcane growing areas in the World (Khan and Jamil, 1983). Historically famous for sugar, this crop has now attained a significant nadir for biofuel production (Mino, 2010).

Sugarcane, a perennial grass, is exposed to all sorts of biotic and abiotic adversaries. The variation in weather parameters like sunlight, temperature, rainfall, humidity and solar radiation affect the different phases of growth like germination, tillering, cane formation and cane stalk elongation, as well as the maturity and ripening phases of plant (Malik, 2009).

13.1 Introduction

Citrus is one of the important fruit crops in India with the production of 111.47 lakh tons from 10.78 lakh hectares with the productivity of 10.34 tons/ha at national level as compared to 25-30 tons/ha in advanced citrus producing countries (NHB, 2013). The productivity and quality of citrus is severely affected by several factors; insect pests being one of them. More than 250 insect pests were reported to attack citrus in India. A total of  22 insect species  in Punjab (Atwal, 1976) ; 50  insect species  in  Karnataka;  42 insect species  in  North-Eastern Hilly region (Pathak and Rao, 1999);  20 insect species in West Bengal and  about a dozen  insect species  in central India have been reported on different citrus cultivars. Further, the pest occurrence and distribution in India indicated that about 21 species are common throughout the citrus growing areas and remaining species may occur in some areas either occasionally or rarely. Of the reported insect pests, Asian citrus psyllid (Diaphorina citri Kuwayama), citrus blackfly (Aleurocanthus woglumi Ashby), whitefly (Aleurolobus marlatti (Quaintance) and Dialeurodes sp.), leaf-miner (Phyllocnistis citrella Stainton), lemon butterfly (Papilio demoleus Linn.), leaf folder (Psorosticha zizyphi Stainton), aphids (Aphis spp. and Toxoptera spp.), thrips (Scirtothrips spp.), mealy bugs (Planococcus citri Risso), scales (Coccus hesperidus Linn), fruit sucking moth (Eudocima spp.), fruitfly (Bactrocera sp.), citrus trunk borer (Anoplophora versteegi Ritsema), bark eating caterpillar, lndarbela spp.

Introduction

Banana (Musa sp; family: Musaceae) is the most popular commercial soft fruit crop grown in equatorial and subtropical regions of the world and also serves as a staple food since the dawn of recorded history in many countries (FAO, 2012). It has bounties of significance to the human beings and is one of the 4th most important food in the world after rice, wheat, and maize. Musa species grow in a wide range of environments ranging from the edible bananas and plantains of the tropics to cold hardy fiber and ornamental plants. They thrive well in an average annual temperature of 20^°C and well distributed rainfall of 200 cm per year (Simmonds, 1959; Wardlaw, 1961). Banana is a large, perennial, monocotyledonous herb 2-9 m in height that arises from large, subterranean rhizomes called ‘corms’. Musa fruits are variable in size, shape, and color. They are generally elongate cylindrical, straight to strongly curved, 7-40 cm long, and 2-8 cm in diameter. The fruit apex is an important attributes in variety identification.

11.1 Introduction

Tropical Root and Tuber Crops serve as primary or secondary staple to meet the calorie needs of one fifth of world’s population. These crops have myriad and complex roles to play in the food security and reduction of hunger and elimination of poverty. The starch content, pharmaceutical and nutraceutical value endow these crops with an extra ordinary range of potential and uses. Root and tuber crops are also greater sources of industrial raw materials for biodiesel and starch derived materials.

10.1 Introduction

Grain legumes such as chickpea, pigeonpea, cowpea, field pea , lentil, ,  and Phaseolus beans are the principal source of dietary protein among vegetarians, and are an integral part of daily diet in several forms worldwide. They are an important component of cropping systems to maintain soil fertility because of their ability to fix atmospheric nitrogen, extract water and nutrients from the deeper layers of the soil as compared to cereals, and add organic matter into the soil through leaf drop. However, grain legumes are mainly grown under rainfed conditions and the productivity levels are quite low mainly because of severe losses due to insect pests and diseases.  Average grain yield of pulses (0.86 t/ha) is only about one-fourth the average yields of cereals (3.54 t/ha).  Production and productivity of grain legumes is constrained by several biotic and abiotic factors, and suffer an average of 31.9 to 69.6% loss in crop productivity due to insects, diseases, drought, weeds,  and soil fertility. Pod borers (Helicoverpa and Maruca), Fusarium wilts, viral diseases, Ascochyta blight and Botrytis gray mold (Chen et al., 2011).

9.1 Introduction

Cereal crops are of global importance and the lifeline of the human civilization. The four most important cereals grown for human food in the tropics are rice, maize, sorghum and pearl millet. There are other minor cereals of tropical origin which are of local importance in the tropics. These include finger millet (Eleusine coracana), a staple food in parts of East and Central Africa; barnyard millet (Echinochloa frumentacea), cultivated in India and Southeast Asia; foxtail millet (Setaria italica), grown in parts of India; and teff (Eragrostis tef), which is confined to the Ethiopian highlands. The winter cereals wheat and barley are also grown to a limited extent in the tropics, largely at high altitudes: for example, wheat in Kenya and barley in Ethiopia. Wheat and barley are important crops in the Indian subcontinent, and are grown there in the cool season at low altitudes, but the bulk of the crop area lies outside the tropics.

8.1 Introduction

Vegetables are cultivated over an area of about 19 million ha globally, with an annual production of 268 million tonnes; Asia and Africa account for more than 90% of the hectarage and production (FAO, 2011). Vegetable crops contribute to human and environmental health. Most vegetables can supply plant proteins, vitamins (especially vitamins A and C), folic acid, minerals such as iron and calcium, and dietary fiber to the human diet (Fowler, 2011). Vegetable legumes also fix atmospheric nitrogen in the soil, thus improving soil fertility. Their haulms can be used as high quality livestock fodder. Most vegetables are high-value, repeat-cycle crops that can help lift small-scale farmers out of poverty in developing tropical countries (Genova et al., 2010). However, vegetable production is often constrained by several severe biotic- and abiotic factors that reduce yields and profits.

7.1 Introduction

Sustainable agricultural systems must be adopted to increase the food production keeping in view of increase in human population. In tropical countries, insect pests are major challenges to increase food production by causing significant damage in the crop fields and stored grains and their products. Interventions by implementing timely integrated pest management strategies are necessary to reduce the yield losses. Efforts to control insect pests have predominantly relied on the use of broad-spectrum insecticides.  However, indiscriminate and irrational applications of insecticides have created the problems such as insecticide resistance, resurgence, secondary pest outbreak and the presence of residues in food and environment (Ansari et al., 2013). Globally, to reduce the pesticide dependence, various technologies have been developed using different approaches to monitor and maage insect pests which are discussed in this chapter.

6.1 Introduction

The sensitivities of plants and of crop yield to a changing climate, is a major challenge for the agricultural research community to relate these findings to the broader societal concern with food security. This chapter reviews the direct effects of climate on both crop growth and yield and on plant pests and pathogens and the interactions that may occur between crops, pests, and pathogens under changed climate. The better understanding of the roles of pests and pathogens in crop production systems that might   make to enhanced food security is discussed. Evidence for the measured climate change on crops and their associated pests and pathogens is starting to be documented. Globally atmospheric CO₂ has increased, and in northern latitudes mean temperature at many locations has increased by about 1.0–1.4 ^°C with accompanying changes in pest and pathogen incidence and to farming practices. Many pests and pathogens exhibit considerable capacity for generating, recombining, and selecting fit combinations of variants in key pathogenicity, fitness, and aggressiveness traits that there is little doubt that any new opportunities resulting from climate change will be exploited by them.

5.1 Introduction

Rainfed agriculture accounts for about 60-95% of farmed land in major areas of the world covering Saharan Africa, Latin America, North Africa and East Asia and South Asia. Agriculture in about 60 percent of 142 m ha of net cultivated area in India is rainfed without access to any source of irrigation. Rainfed agriculture is mostly practiced in arid, semi-arid and sub-humid regions where the rainfall is low in quantity, erratic in distribution and is also characterized by high inter-year variability. Together with poor and degraded soils, this limits the length of growing season as well as the choice of crops that can be grown sustainably. Coarse cereals, pulses, oilseeds and cotton dominate the cropping pattern in the regions where rainfed agriculture is concentrated. More importantly, these rainfed regions provide a livelihood to a majority of the rural poor, and as a result they are often described as concentrations of mass poverty and hotspots for civic strife. The productivity of crops grown in rainfed areas is considerably lower than its potential and much lower than that of irrigated crops. Enhancing the productivity of rainfed crops is therefore important from the viewpoints of growth, equity and sustainability.

4.1 Introduction

Insecticides, biocontrol agents and resistant varieties are the three important pest management tactics in vogue across the globe. Though several biocontrol agents have been recorded on major pests of economically important crops, mass multiplication techniques for most of them are yet to be perfected, and in several instances, the inundative releases of natural enemies are costlier than chemical insecticides. Moreover, unlike perennial crop ecosystems, the annual crop ecosystems like rice, cotton, sugarcane, pulses, etc. are frequently disturbed and hence, inoculative releases of biocontrol agents are often impractical. Above all, in spite of sustained effort from dedicated plant breeders across the globe, the resistant varieties with outstanding yield potential are very limited in numbers. Genetic engineering of crop plants though paved the way for introducing insecticidal genes more precisely and efficiently, the poorly understood ecological and sociological implications of genetically engineered crops in their target environment resist their strong footing in the pest management programmes in most of the crops especially of food crops. In this backdrop, insecticidal interference is inevitable to manage the insect pests, and they are the only weapon whenever the pest population crosses the economic threshold level.

Introduction

The tropics extends on  vast region of the earth surface ranging from 23½^°C North to the Tropic of Cancer and 23½^°C South to the Tropic of Capricorn. Several countries of Asia, Africa and Latin America include tropical areas. The tropical regions are the warmest area on the earth with average temperatures ranging between 20^°C and 35^°C. More than 80 % of the area in tropics supports forests and savannah and only 15% is under deserts, shrubs and grasses. About 5% of the area is under mid or high altitude with moderate climatic conditions. Evidently, the tropics support great diversity of physical and climatic conditions in different ecologies and different ecosystems. Temperature and daylight length is much higher throughout the year which induces more number of insect pests, their generations causing more damage in tropics. The increased menace of insect pests requires frequent and repeated use of chemical pesticide to mitigate the insect pest damage.

1.1 Introduction

The human population is growing rapidly at an alarming rate, disproportionately to the production of food supplies, which will necessitate production of more food in the near future. The human population has already crossed the 7 billion mark and is expected to rise over 8-10 billion by 21st century. More than 800 million people are reported to suffer from malnutrition (Matson et al., 1997).  Thereby necessitating the need for more food production. Presently, agriculture faces the double challenge of feeding a fast growing population and at the same time prevents the degradation of the agricultural resource base. There appear to be two options for developing countries; either to improve agriculture through modernization, by emphasizing pesticides, fertilizers, machinery and modern varieties of crops; or use sustainable agriculture, promoting improved traditional, small-scale techniques (Pretty, 1999).

The potential yield levels in major crops have reached almost to a plateau. The current world population of 7 billion is likely to reach 9 billion by 2050 putting huge pressure to produce more from the available arable lands as acreage of major crops is predicted not to increase any further. The deficit of food requirements will have to be met partly by bridging the gap between farm yield (the average yield of the crop in a particular region/country/world) and the potential yield (the yield obtained usually in the breeders’ plots grown across the region of interest with the best yielding new varieties and without biotic stresses as diseases and pests, and abiotic stresses such as drought, flooding, salinity, heat and cold and partly by increasing potential yield per se.

No society can ever desire to achieve a long-term goal of sustainable development unless it builds upon its own knowledge, traditions, ethical foundations and technological endowments. The knowledge of the people particularly in drought and flood prone regions, hill areas, tribal areas and other high risk environments, has to become a building block of new technological improvements. Knowledge happens when our expectations are belied, modified and sometimes confirmed. Because the asymmetry in our expectations is influenced by our access to resources, institutions, technology and cultural platforms, we get different kinds of knowledge, even when we confront similar situations Gupta (2005). In any community living close to nature, asymmetry in knowledge generation and its utilization is inevitable. The experts exist not just in our profession, but in every profession.

Introduction
 
Intellectual property is a cluster of legally recognized rights associated with innovation and creativity, the works of the mind, as against physical products, land and other tangible resources. Even though it is intangible, intellectual property (IP) is often recognized as personal property, to be sold and traded like other forms of property. Under intellectual property law, owners are granted certain exclusive rights to various markets, machines, musical, literary, and artistic works; discoveries and inventions; and applications. But national laws normally don’t define ‘intellectual property’ as a single property right. Instead, ‘intellectual property’ is used as a convenient general term describing a range of distinct legal rights, relating to literary, artistic and scientific works; performances of performing artists; phonograms, and broadcasts; inventions in all fields of human endeavour; scientific discoveries; industrial designs; trademarks, service marks, and commercial names and designations; protection against unfair competition and all other rights resulting from intellectual activity in the industrial, scientific, literary or artistic fields.

Introduction

Indigenous peoples established distinct systems of knowledge, innovation and customary practices from their centuries old interactions with the local biodiversity and environment, relating to the uses and management of local natural resources. Today, this knowledge is looked as an important resource for research and development in different areas such as pharmaceuticals, agriculture, veterinary, jewelry, fashion and cosmetic products. This has led to rampant exploitation of such knowledge disregarding the customary practices and rules of indigenous peoples holding and preserving such knowledge as well as the biodiversity and natural resources. As a consequence, the traditional knowledge is under threat of being misappropriated or lost.

What is Indigenous Knowledge?

Indigenous knowledge (IK) is the local knowledge which is considered as the social capital of the poor. It is their main asset to invest in the struggle for survival, to produce food, to provide for shelter and to achieve control of their own lives. Indigenous knowledge is a cumulative body of knowledge, practices and manifestations maintained and developed by people with long histories of interaction with their natural environment. It forms the basis for local-level decision-making in agriculture, health, natural resource management and other activities, especially for the poor, and provides problem-solving strategies for communities (World Bank, 1998). IK is a tacit knowledge that is not easily codifiable and unique to a particular culture and society.

1. Introduction

Antheraea assamensis is lepidopteron insects of Assam which is commercially utilized for the heritage golden silk “muga”. Rearing of muga silkworm is one of the most significant traditional handloom industries restricted only to the North Eastern Region of India (N.E. India) and plays a major role in the rural economy.  Considering the ecological conditions, food plant distribution, presence of eco-types and species of diverse nature in co-existence, it is speculated that this region is a possible home of origin of Antharaea, from where radiations would have occurred (Neog et. al., 2010). Despite the fact that N.E. India is the original home of muga, earlier studies have shown that the population is declining due to depletion in genetic variability (www.cdfd.org.in/wildsilkbase/info_moths.php).

Introduction

Northeastern Region of India consists of eight States, viz., Arunachal Pradesh, Assam, Manipur, Meghalaya, Mizoram, Nagaland, Tripura and Sikkim.  The northeastern states are located between geographical ordinates, 21° to 29°30' N and 89°46' to 97°30' E. The region, surrounded almost on all sides by Bhutan, China, Myanmar and Bangladesh, which can be broadly divided into two characteristic zones viz., Mountainous and Plain. Although distinguished in the altitude differences, both the mountain and plain are closely interrelated in terms of natural resource sharing and economic flow. According to the physiographic characters this region is divided into five physiographic units, the Assam Himalayas, the Brahmaputra valley, the Shillong plateau, the Barak valley and the Southeastern hill region. Except the Brahmaputra and Barak valleys in Assam and the Imphal valley in Manipur, the terrain is hilly and mountainous, only making 65% of the northeast an undulating land with elevations ranging from 200 to 900 m above MSL

Introduction

“Quality” of fish refers to the aesthetic appearance and freshness or degree of spoilage which the fish has undergone or involves safety aspects such as being free from harmful bacteria, parasites or chemicals. “Quality’’ is a term which must be defined in association with an individual product type. For example, it is often thought that the best quality fish is the one which is consumed within the first few hours of post mortem. However, very fresh fish which are in rigor mortis will be of hard texture and difficult to fillet and skin are often unsuitable for smoking or drying. Thus, for the processor, a slightly older fish which have passed through the rigor process are more desirable.

Evolution of Computer technology and advent of database concept have provided enormous opportunities to the  scientist, researchers and managers of diverse field  to create, manipulate integrate, link and analyse their data in order to generate information and knowledge. The research projects involving exploration, survey and collection of data, generally create database to maintain and analyze the data.  Almost in every sphere of life and industry this database concept/technology is used in one form or other.  Scientists and researchers of life sciences realized the importance of the database and used this technology to develop databases of different types/groups of living organisms. The database technology has eased the difficulty in designing, developing and maintaining the complex information systems.

Introduction

ICT may be defined as technologies that facilitate communication and the processing and transmission of information by electronic means. ICT is an acronym that stands for Information Communications Technology and refers to technologies that facilitate communication and the processing of information by electronic means and includes everything from radio and television to telephones (fixed and mobile), computers and the internet. Information and communication has become an increasingly powerful tool for improving the delivery of basic services and enhancing local development opportunities. Recent years have seen increases in the use of ICT in almost all spheres of rural life. Especially, the rural communities require information among others on supply of inputs, innovations, improved technologies, credit, market prices and competitors. Since the concepts, methods and applications involved in ICT are constantly evolving on an almost daily basis. It’s difficult to keep up with the changes - they happen so fast.

1. Introduction

An expert system is defined as “a computer program designed to model the problem solving ability of a human expert” (Durkin, 1994). It is also defined as “a system that uses human knowledge captured in a computer to solve problems that ordinarily require human expertise”. An intelligent computer program that uses knowledge and inference procedures to solve problems that was difficult enough to acquire significant human expertise for their solutions. It is a computer application that solves complicated problems that would require extensive human expertise. To do so, it simulates the human reasoning process by applying specific knowledge and interfaces. Expert system also uses human knowledge to solve problems that normally

Abstract

Crop cultivation is a complex process and involves a set of activities like land preparation, planting, pest control, irrigation, nutrient management, harvesting, marketing, etc. Entire cycle of crop production requires multitude of information by the farmers. Despite many efforts over the years to disseminate and transfer agriculture knowledge to the stakeholders, large amounts of expertise and knowledge are still out of reach to most of them. Agriculture knowledge may be contained in the corporate database, or it may reside undocumented inside the brain of the researchers or even stored in locations unknown to the majority of the people in the organization. Large sections of the farming community, particularly the rural folk, do not have access to the huge knowledge base acquired by agricultural universities, extension-centers and businesses. In this respect the main challenge is to find this knowledge and apply it to the decision making process involved in agriculture development.

Establishment of databases and data warehouse; knowledge discovery from database/data warehouse (KDD) and development of the mechanism of dissemination of knowledge on information networks as per requirements of user groups is gaining importance now a days. Since there is a large number of data collection agencies and equally diverse resources for which the information is collected, it is easy to visualize the heterogeneity of information. The problem is compounded by the fact that there are no common standards that are applied in data collection. Designing data warehouses to integrate the collected information poses a formidable challenge to any data warehouses architect. In order to use the information for planning and decision-making level, data have to be integrated and aggregated properly.

The term bioinformatics was coined by Paulien Hogeweg in 1979 for the study of informatics processes in biotic systems. It was primarily used in genetic and genomic studies, particularly in those areas of genomics involving large-scale DNA sequencing. Bioinformatics involves application of information technology to store, organise and analyse the vast amount of biological data available in the form of sequences and structures of proteins (the building blocks of organisms) and nucleic acids (the information carrier). There are umpteen ways to define bioinformatics, mainly owing to its rapid evolutions.

Abstract

The field of bioinformatics emerged as a tool to facilitate biological discoveries more than 10 years ago. Structure prediction is fundamentally different from the inverse problem of protein design. Protein structure prediction is one of the most important goals pursued by bioinformatics and theoretical chemistry; it is highly important in medicine and biotechnology. Structure prediction is fundamentally different from the inverse problem of protein design. While the genome of many organism have been sequenced over the last few year, transforming such raw sequence data into knowledge remains a hard task. A great number of prediction program for genes have been developed hat try to address this problem, which consists of locating the genes along a genome.

Abstract

Protein-protein interactions play a major role in most cellular processes. Many essential cellular processes such as signal transduction, transport, cellular motion and most regulatory mechanisms are mediated by protein-protein interactions. The study of protein-protein interactions is of great importance in determining the biological function and impact of proteins. The experimental techniques remain expensive, time-consuming and labor-intense. Computational methods play an important role at all the stages of determining protein-protein interactions. In this chapter, we describe the different types of protein-protein interactions, computational methods, currently available databases and tools, protein-protein docking and as well as protein-protein interactions as drug targets.

1. Introduction

Protein–protein interactions serve as the hub of the functioning of a living cell, coordinate biological processes as well as form core for interactomics system of living organisms. Various biological processes as signal transduction, cell-cell communication, ingestion or expulsion of any macromolecule, host parasite interaction, diseases as cancer and many other metabolic networks employ protein–protein interactions. During such a process two or more proteins interact transiently with each other or form complex for a long period of time. Thus attempts have been made for years to study comprehensive mechanism of such protein–protein interactions by various branches of sciences such as biochemistry, quantum chemistry, molecular dynamics, chemical biology and signal transduction. The availability of three-dimensional (3D) structure of proteins is a prerequisite for understanding functions of protein complexes at a molecular level as well as amino acid interactions within a complex.

Key words : CAVD, Drug Design, Bioinformatics, CADD, Co-factor, Vaccinology, infectious diseases, Jenner, immunity, Molecular modeling, Immunoinformatics, Antigen, Antibody, Live Vaccine, Alive Vaccine, Protein-peptide, Enzyme, Tools for Vaccine design,
 
Vaccine – Prevention is Better than Cure

A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe, its toxins or one of its surface proteins. The agent stimulates the body’s immune system to recognize the agent

Introduction

Data Mining is a complex subject that describes a type of database application used to search large amounts of data for patterns using specific tools. Advanced statistical methods and tools such as classification, association rule mining and cluster analysis search large volumes of data for previously unknown relationships within the data. Data Mining can be used to decipher trends in a wide variety of fields such as computer science, the marketing and advertising of goods, services or products, artificial intelligence research, biological sciences and high-level government intelligence. Data mining is a logical process that is used to search through large amounts of information in order to find important data.

Databases

A database is a collection of information that is organized so that it can easily be accessed, managed, and updated. Databases can be classified according to types of content: bibliographic, full-text, numeric and images and by their application area, for example: accounting, music compositions, movies, banking, manufacturing, or insurance. The term database may be narrowed to specify particular aspects of organized collection of data and may refer to the logical database, to the physical database as data content in computer data storage or to many other database sub-definitions.

Abstract

Last few decades have witnessed an immense technological advancement in the education sector in India. With an advancement of technology, new gadgets are flooding the Indian market continuously bringing an immense opportunity for the education sector to improve upon the course delivery system. Higher education sector in India is adopting such new technologies in course delivery at a slow pace; however, there remains still a far way to traverse for the Indian education sector in order to achieve a perceptible and effective technology-infusion in the academic delivery arena. This paper is devoted to present an expository review on the usefulness of new gadgets, like smart phones, e-book reader as well as tablet PC, in both class-room education-delivery segments as well as in distance education sector in India.

Abstract

Fusion is a well known entity in various fields (e.g. medical imaging, weapon detection, flood monitoring etc.) that surmises information originating from several modalities. This chapter is an attempt to assort the various image fusion techniques available for human face recognition and to put a review of the advancements being made by the different researchers. The various types of fusion those have been used or may be used for face recognition have also been discussed here.

1. Introduction

With the fairly recent advent of inexpensive, rapid sequencing technologies that continue to improve sequencing efficiency and accuracy, many species of animals, plants, and microbes have annotated genomic information publicly available. It is important to use this genomic information for the identification and isolation of novel and superior alleles of important genes from gene pools of the organisms

Abstract

The study of computational toxicity prediction is very crucial and necessary, as it is quite time consuming and expensive to measure the toxicity via experimental techniques (Quan Liao et al., 2006). The use of computational approaches particularly to reduce the time and cost for the evaluation of the kinetic and toxic behaviour of any drug has been increased tremendously in recent time period (Richard Judson et al., 2004). Machine learning is a powerful tool to discover new complex combinatorial relationships in various in vitro and in vivo data information (Richard Judson et al., 2004) and has been successfully used in many diverse fields with numerous applications such as pharmacodynamics properties prediction (Czerminski et al., 2001; Livingstone et al., 2003), protein function prediction (Cai et al., 2003), medical decision making (Veropoulos, 2001), spam categorization (Drucker et al., 1999), detection of oil spills (Kubat et al., 1998), and speech recognition (Nuttakorn et al., 2001).

Introduction

The capabilities and effort to collect the geographic data has increased dramatically in the last decade to cope up with the increasing demand for the support of decision making and planning process in the state, national and global level.  From the Government sector, there is a need for spatial data to make quick responses to natural disasters, industrial accidents and environmental crises as actions will be decided based on geography. There is constant pressure to make wise decisions in a more time and cost effective and efficient manner. Accurate and current geospatial data are critical to these decisions.

1. Machine Learning

Learning denotes changes in a system that enable a system to do the same task more efficiently the next time (Simon, 1983)or Learning is constructing or modifying representations of what is being experienced (Ryszard Michalski et al., 1986). Machine learning is a scientific discipline concerned with the design and development of algorithms that allow computers to evolve behaviors based on empirical data, such as sensor data or databases. A learner can take advantage of examples (data) to capture characteristics of interest of their unknown underlying probability distribution. Data can be seen as examples that illustrate relations between observed variables. Discover new things or structure that is unknown to humanseg. data mining.A major focus of machine learning research is to automatically learn to recognize complex patterns and make intelligent decisions based on data.

Abstract
    
The amount of data being collected across a wide variety of fields today far exceeds our ability to reduce and analyze without the use of automated analysis techniques. In addition, the whole data may not be of user interest and imperfect. Therefore, it is very challenging to organize this data in formal system, which provides outputs in more relevant, useful, and structured manner. There are many techniques available to retrieve knowledge from this voluminous data. This paper discusses different rough computing based information retrieval techniques to obtain meaningful knowledge from large amount of datasets. We also discuss a real life example to show the viability of proposed research.

Abstract

Currently, computers are changing from single, isolated devices into entry points to a worldwide network of information exchange and business transactions called the World Wide Web (WWW).Current web contains billions of documents and has many administrative problems and limitations; in addition to that the web content is still accessible only to humans. For this reason, support in data, information, and knowledge exchange has become a key issue in current computer technology. The success of the WWW has made it increasingly difficult to find, access, present, and maintain the information required by a wide variety of users. In response to this problem, many new research initiatives and commercial enterprises have been set up to enrich available information with machine processable semantics.

Introduction

The role of knowledge management as the key source for competitive advantage in our organizations has become a hotly debated topic. Indeed, it is a core competency for creating competitive advantage. In this environment that knowledge management is vital, therefore, at first we should determine knowledge management situation, and then to achieve a desired point, formulate a knowledge management strategy.