eChapters

1. Introduction

Protein–protein interactions serve as the hub of the functioning of a living cell, coordinate biological processes as well as form core for interactomics system of living organisms. Various biological processes as signal transduction, cell-cell communication, ingestion or expulsion of any macromolecule, host parasite interaction, diseases as cancer and many other metabolic networks employ protein–protein interactions. During such a process two or more proteins interact transiently with each other or form complex for a long period of time. Thus attempts have been made for years to study comprehensive mechanism of such protein–protein interactions by various branches of sciences such as biochemistry, quantum chemistry, molecular dynamics, chemical biology and signal transduction. The availability of three-dimensional (3D) structure of proteins is a prerequisite for understanding functions of protein complexes at a molecular level as well as amino acid interactions within a complex.

INTRODUCTION

The enemies of plants have been harming the organized agriculture ever since man started depending on plants for food. Fossil evidence indicates that plants were affected by disease since 250 million years ago. Conditions of food shortage and famines have been created by these enemies of plants. Naturally, the man had been obvious of their presence and proposed explanations and methods of combating them according to the knowledge available at that time all over the world. It is not true that attention to plant diseases was first given in the western countries. In the ancient Indian literature many plant diseases and their remedies were mentioned.

Dairy buffalo production has been a tradition in parts of the world like the Caucasian countries. Asia and Egypt, where fresh buffalo milk, dahi (cultured sour milk), ghee (butter oil) and yoghurt are popular. In Italy the dairy buffalo industry is flourishing thanks to the popularity of buffalo mozzarella cheese. Because of the market for Mozzarella, buffalo farming is a profitable enterprise and is carried out in an organized manner with modern equipment. In South American countries like Brazil and Argentina, buffalo reared for both milk and meat. In recent years buffalo milk and milk products, especially Mozzarella cheese, have become immensely popular and dairy buffalo production has founds its way into non traditional areas with the number of buffalo farms mushrooming.

Fish production of the country has improved considerably in the post-independent India with the total production going up from 7.52 lakh tons in 1950-51 to 90.4 lakh tons in 2010-11, with an average growth rate of 4.35% per year after 1990. The real jump has come from inland aquaculture sector. Production from inland waters which used to be less than 30% of the total till sixtees, gradually rose at a fast pace and crossed the 50% mark by the end of 20th century. The present contribution of inland sector to the country’s total fish production of 52.09 lakh tons is 58% recording an average annual growth rate of 8.4% per year after 2011.

This increase in contribution from inland sector is because of the quantum jump in production from freshwater aquaculture, made possible mainly due to development of technologies of hypophysation of Indian Major carps and composite fish culture during late fiftees and sixties respectively. Development of these two technologies, along with their wide extension through Fish Farmer’s Development Agency, initiated by Govt. of India in latter part of 1970s, have in fact revolutionised freshwater aquaculture scenario of the country. It is presently contributing to over 70% of the total fish production  from inland resources of this country.

Air, water and land constitute our environment and these are technically known as atmosphere, hydrosphere and lithosphere respectively. All these spheres together constitute the biosphere. In the biosphere, apart from human beings, plants, animals, birds, fishes, insects and microorganisms also exist. All these living beings get affected whenever a change, physical or chemical occurs in the biosphere. This change is termed as pollution and the agents that institute these changes are called pollutants. A kind of pollution that has come in to prominence more recently is radiation, causing environmental and health problems of immense magnitude. The radiation may either be natural like cosmic radiation from outer space and sun?s radiations or produced by disintegration of naturally occurring and manmade elements. Such radiation is not visible to our eyes, but can penetrate the body and do immense harm. Man and animals have been continually exposed to different sources of radiation. But the radiation levels were well within the tolerable limits in the past. Yet, since the mid 1970?s human activities have been changing the chemistry of atmosphere in a way that reduces the amount of ozone in the stratosphere which is responsible for protecting the living things from excessive amounts of ultraviolet radiation. Further, it is only after the advent of nuclear power stations that radiations increased to reach harmful levels. Though mankind has benefitted by harnessing nuclear energy for peaceful purposes, one cannot deny the inherent dangers of radiation. Nuclear power plants no doubt help in the production of controlled electricity. However, a worldwide controversy is ragging over the existing nuclear power plants and setting up of new plants particularly since 1986 disaster of Chernobyl nuclear plant in Russia. A fire in the plant allowed massive amounts of radiation to be released into the atmosphere. This fall out drifted into the Scandinavia and Eastern Europe causing enormous damage to crop and livestock.

Abstract

Grain size distribution patterns of five rivers – Hooghly, Bhagirathi, Damodar, Ajoy and the Usri, were critically analyzed and compared with three model distributions: log-normal, log-hyperbolic and log-skew-Laplace. The log-normal and log-skew-Laplace are the limiting distributions of log-hyperbolic family. The Hooghly-Bhagirathi river system from where the sand samples were collected is tidal in nature whereas the other three rivers are non-tidal. The tidal effect on grain size distribution patterns was also studied. Bed load samples were collected from the foreset of different bedform sizes. A total number of 126 sediment samples were collected from different sections of the rivers under study.

It is observed that the grain size distribution pattern of the tidal stretch of the Hooghly-Bhagirathi river system has a tendency of attaining a log-skew-Laplace distribution model whereas the other three non-tidal river sediments show a clear log-normal distribution pattern as a best-fit statistical model.

A possible reason has been attributed. During prolonged transport of bed material, the coarser and finer sediments are separated in the following manner: coarser sediments are buried below the advancing ripple fronts whereas the finer sediments are transported further downstream as suspension load. As a result, sediments of a narrow range of size classes are active in the distribution pattern giving rise to symmetric and unimodal distribution patterns which are the main criteria of log-normality. On the other hand, due to the upstream and downstream movement during sediment transportation in tidal reaches, the same sediments are constantly reworked and the segregation of different size fractions is hindered causing a log-skew-Laplace distribution pattern.

Ridge gourd, Luffa acutangula and sponge gourd, Luffa cylindrica under the family Cucurbitaceae (Chromosome number: 2n = 2× = 26) is an important warm season fruit vegetable crop. Ridge gourd is widely cultivated in India, Southeast Asia, China, Japan, Egypt and other parts of Africa. Sponge gourd is now cultivated in all tropical regions of the world. It was an important crop used for industrial filters until World War II and Japan cultivated the best crop for this purpose. The main commercial production areas of sponge gourd today are China, Korea, India, Japan, Central America and Brazil. Immature fruits of ridge gourd and sponge gourd are eaten as a vegetable and at maturity both become very fibrous. The word luffa or ‘loofah’ is of Arabic origin and the sponge characteristic of the crop has been described in old Egyptian writings.
Fruits are good sources of vitamin C, riboflavin, zinc and antioxidants. It is effective in balancing blood sugar levels, help eliminate toxic waste and prevent fat accumulation. Ridge gourd also helps reduce excessive body heat during summers which can prevent many ailments.
 

Classifying wool is crucial in the textile sector for upholding quality standards, enhancing processing techniques, and ensuring that wool satisfies particular market demands. Precise classification aids in choosing the appropriate wool type for a variety of products, ranging from apparel to carpets, and guarantees uniformity and performance across diverse applications.
Classification of Wool: Wool is categorized in a manner akin to hides and skins, based on its intended application. It is divided into three primary types according to fibre length: combing wool, clothing wool, and carpet wool. Long fibres are combed and twisted to produce worsted yarn, whereas shorter fibres are carded and blended in various directions to create woollens. Carpet wool is characterized by an average fineness of 30 to 50 μm and a medullation percentage between 15% and 68%. The quality of wool is influenced by factors such as breeding conditions, climatic conditions, diet, and overall care. For example, excessive moisture can strip natural grease, while colder climates lead to tougher, heavier fibres. Consequently, wool can be classified in two distinct manners:
A. By the sheep from which it is sourced, and
B. By fleece

Introduction

While world population is expected to increase from 6 billion to about 8.3 billion, India is likely to be the most populous nation with 1.6 billion in the year 2030. Therefore, it is essential to be prepared to produce sufficient food for the increased population with the application of newer technologies. The consumption of animal food was 10 kg/yr in the 1960s increasing to 26 kg/yr in 2000 and is expected to be 37 kg/yr by 2030 (FAO, 2008; 2009). Large increases in per capita and total demand for meat, milk and eggs are forecast for most developing countries for the next few decades (Delgado et al., 1999). In developed countries, per capita intakes are forecast to change slightly, but the increases in developing countries, with their larger populations and more rapid population growth rates, will generate a very large increase in global demand.

Moreover, an increasing number of consumers demanding healthy and quality foods have pushed researchers into development of technologies that can control the proportion of lean and fat muscle deposition in meat producing animals. A number of technologies have been developed that led to remarkable improvements in the efficiency of animal production and in carcass composition and meat quality. There are some dietary additives and vitamins that may increase protein and muscle deposition, while often simultaneously reducing fat deposition by modifying nutrient metabolism in individuals.

Fish culture is an age old tradition modified and improved by several scientific inventions. Farmers can easily take up fish culture in village ponds, tanks or any water body and can improve their financial position substantially. Pond aquaculture is the most common method of fish culture throughout the world. For successful aquaculture of fish, molluscs, crustacean and even aquatic plants, the water and soil in which fish are grown should have favourable conditions for their growth which, in turn, is intimately linked with several physical, chemical, biological characteristics of water and management practices adopted. Physical and chemical characters of the soil and water will affect the primary and secondary production of water bodies.

The survival and production of fish in a pond is dependent on the primary and secondary production. Primary production depends on the water quality parameters. Phytoplankton make carbohydrate using sunlight and releases oxygen. This is the major source of energy and oxygen in the ecosystem. Zooplankton which feed on the phytoplankton form major source of food for the fishes.

Guava (Psidium guajava L) is an important fruit crop of India. It has gained considerable prominence on account of its high nutritive value, availability at moderate prices, pleasant aroma and good flavour. It is one of the commonest fruits liked by the rich and the poor and is popularly known as the ‘apple of tropics’. It is one of the hardiest fruit trees adaptable to a variety of soil and climatic conditions. It comes up well even under neglected conditions and in fact it is even considered sometime as a weed in Fiji and Hawaii. Guava fruit is relished when mature or ripe or when freshly plucked from the tree. It is also used for many commercial products like jelly, fruit butter, juice, etc.The guava is said to have originated from tropical America (Hayes, 1953). De Candolle (1904) stated that it originated in Mexico, while Purseglove (1968) opined that it originated in Brazil. It is widely distributed all over the equatorial regions of tropical and sub-tropical climate. It was introduced to India during the 17th Century. In Spanish, the tree is known as guayabo, or guayavo, the fruit guayaba or guyava. The French call it goyave or goyavier; the Dutch, guyaba, goeajaaba; the Surinamese, guave or goejaba; and the Portuguese, goiaba or goaibeira. Hawaiians call it guava or kuawa. In Guam it is abas. In Malaya, it is generally known either as guava or jambu batu, but has also numerous dialectal names as it does in India, tropical Africa and the Philippines where the name, bayabas, is often applied. Various tribal names–pichi, posh, enandi, etc., are employed among the Indians of Mexico and Central and South America.

13.1 Introduction

Geothermal energy is the nature-based heat generated from within the earth. Underneath the earth’s relatively thin crust, temperature range from 1000 to 4000°C & in some areas, pressures exceed 138 MPa is available. Geothermal energy is most likely generated from radioactive thorium, potassium and uranium dispersed evenly throughout the earth’s interior which produce heat as part of the decaying process. This process generates enough heating, keep the core of the earth at temperature approaching 400°C. Composed primarily of molten nickel & iron, the core is thought to be surrounded by a layer of molten rock, the mantle at approximately 100°C. Nine major crustal plates float on the mantle & currents in the mantle cause the plates to drift, colliding in some areas and diverting in others. When two continental plates converge a complex series of chemicals in the form of molten magna rises in the earth’s crust and depending upon its magnitude, it may break the crust and reach at the earth surface. Volcano, hot spring, geysers & fumaroles are natural geothermal resources near the surface and perhaps where economic drilling operations can tap their heat and pressure.

Thermal heating methods are used from long time to decontaminate the food products from microorganism and therefore increase its shelf life and ultimately make the product safe for human consumption. But these methods diminish the sensory, physicochemical and nutritional properties of food (Barba et al., 2012). Also, the cost of generation of heat in manufacture of food product make the product costlier in thermal processing and also create environmental issue.

Objectives • Seminal evaluation and processing • Evaluation of bull fertility on the basis of its seminal characters • To make the Artificial insemination programme successful History Related to Semen Collection • The use of artificial vagina was started by Milovanov for semen collection. Before that method of placing the cotton ball in vagina was used. • AV for Dog was discovered by Amantea in 1914. Milovanov discovered AV for Bull, ram and stallion. Mckenzie discovered AV for boar (1931). • The electroejaculatory method of semen collection was initiated in a bull by Laplaud & Cassou and in ram by Gunn. • Burrows and Quinn (1937) developed the method of abdominal massage and pressure to collect semen in poultry.

1. Introduction

Aquatic algae is present in both contaminated and uncontaminated water sources. serve as essential bioindicators for evaluating water quality. Their sensitivity to pollutants and position in The significance of lower-level organisms in the food chain lies in their invaluable role in comprehending the effects of toxic substances on aquatic ecosystems. (Dwivedi & Pandey (2002). Pesticides, including herbicides, fungicides, and insecticides, play a crucial role in agriculture by utilizing forestry and animal husbandry to improve crop production. However, their indiscriminate use can lead to environmental contamination, which poses significant risks to ecosystems and human health. Pesticide contamination primarily results from surface runoff, emissions during spraying, improper transportation, inadequate spraying practices, and insufficient wastewater treatment from the pesticide industry. Introduction of pesticides into the environment Presents numerous environmental and health risks., inhibiting plant and animal growth and affecting the development and nervous systems of animals Pesticides have the potential to infiltrate the food chain, bioaccumulate in higher trophic levels, and reach the human body through biomagnification. Commonly used pesticides, such as imidacloprid, isoproturon, simazine, atrazine, mecoprop, and glyphosate, along with historical organochlorine pesticides (OCPs), contribute to significant pesticide contamination.

Bitter gourd or Bitter melon, Momordica charantia L under the family Cucurbitaceae (Chromosome no. 2n = 2× = 22) is widely grown in India, Indonesia, Malaysia, Singapore, Thailand, China, Japan, East Africa, the Caribbean and South America for its edible fruit. Tender fruits are widely used as cooked vegetables in a number of ways. Bitter gourd is an excellent source of vitamin C, iron, magnesium, potassium, calcium and ß carotene. The fruits contain non-toxic glycoside momordicin, which gives it bitterness and also health benefits. It also contains an insulin-like compound called Polypeptide-p or p-insulin and steroidal compound “Charantin” having hypoglycemic property.
Origin, domestication and adaptation in India
Wild or semi-domesticated variants spread across Asia in prehistorical period, and it was probably domesticated in Southeast Asia. It has probably originated in eastern India or Indo-Burma area or southern China. Uncarbonized seed coat fragments have been tentatively identified from the spirit cave in northern Thailand however, there have been no archeological reports of bitter gourd remains in China (Marr et al, 2004).Population resequencing revealed the divergence between wild and South Asian cultivars about 6,000 years ago, followed by the separation of the Southeast Asian cultivars about 800 years ago, with the latter exhibiting more extreme trait divergence from wild progenitors and stronger signs of selection on fruit traits.

Description and Distribution
Sweet Flag or Calamus is reported to be common in Kashmir and Kumaon ranges of the Himalayan forests. The rhizomes are collected from the Himalaya forests and brought to Kathgodan, from where they are despatched to Mumbai, Kolkota and Kanuaj. It is a semi-aquatic perennial herb with a creeping and much branched aromatic rhizome. The rhizome is cylindrical or slightly compressed, about 19-25 mm in diameter and about 10 cm long. Externally, it is light brown or pinkish in color, and, white and spongy within. It is thoroughly washed in water, freed from dirt, and rootlets are removed and then carefully dried at a low temperature. It deteriorates with age and is subject to attack by worms. It is this dried rhizome, which constitutes Calamus or Sweet Flag, which is used as a condiment and as a pharmaceutical product . It has a reputation as a healing herb for its use in medicine. It is found wild as a water weed in shallow margins of creeks, lakes, pools and some rivers, throughout India and Sri Lanka, ascending to 1830 meter above mean sea level in the Himalayas. The plant thrives in marshy places and in most situations, like the edges of lakes and banks of streams. It is cultivated in one district , Kotagere, in Karnataka State, India. Curiously enough, the cultivation of Sweet Flag has not been extended to any other part of the State. It is also cultivated in Europe and USA, more for medicinal purposes.
Area, Production And International Trade
No reliable information is available on any of the above aspects in India, except that it is traded both for medicinal and condiment purposes.

Introduction
Antimicrobial resistance (AMR) has emerged as one of the most alarming public health challenges of the 21st century, threatening the effectiveness of life-saving drugs and the future of modern medicine. This crisis is not limited to healthcare settings; it spans communities, agriculture, and the environment, impacting every facet of society. India, with its large population, high burden of infectious diseases, unregulated access to antibiotics, and considerable pharmaceutical manufacturing industry, stands at the forefront of the global struggle against AMR. The rise of resistant microbes stems from a complex interplay of factors: overuse and misuse of antibiotics in humans and animals, poor infection prevention practices, lack of sanitation, and environmental contamination from antibiotic waste. As a result, common infections are becoming harder to treat, surgical procedures riskier, and healthcare costs are escalating, all leading to increased morbidity and mortality. Tackling AMR requires robust intersectoral collaboration—no single stakeholder can succeed alone. Non-governmental organizations (NGOs), industries, and Corporate Social Responsibility (CSR) initiatives form a critical triad in India’s fight against AMR. NGOs drive grassroots education, advocacy, surveillance, and policy change, often bridging gaps where governmental capacity is limited. The pharmaceutical and healthcare industries, responsible for antibiotic manufacturing, distribution, stewardship, and infection control, play a pivotal role in curbing environmental emissions, supporting responsible use, and promoting the discovery of new treatments. Meanwhile, CSR channels the resources and expertise of corporations towards sustainable, communityfacing projects that promote awareness, improve hygiene, foster stewardship, and drive systemic change.

El Nino is the name given to the occasional development of warm ocean surface waters along the coast of Ecuador and Peru. When this warming occurs the usual upwelling of cold, nutrient rich deep ocean water is significantly reduced. El Nino normally occurs around Christmas and lasts usually for a few weeks to a few months. Sometimes an extremely warm event can develop that lasts for much longer time periods. In the 1990s, strong El Ninos developed in 1991 and lasted until 1995, and from fall 1997 to spring 1998.

The last two decades have seen rapid growth and development in the industrial sector as well as urbanization has increased. Due to globalization and mass production of commodities, the situation in the modern world nothing like ever before. Food and dairy industries are also not left out from this massive expansion. Due to changing behavior and food consumption habits too, there has been a surge in the risk of foodborne illness. This has created a problem in terms of public health and sustainability