eChapters

1.0 INTRODUCTION

Among tree spices, nutmeg (Myristica fragrans Houtt) belonging to the family Myristicaceae is the most important, providing two spices, i.e. the nutmeg (dried seed) and the mace (dried aril covering the seed). The latter is more important. Nutmeg is cultivated mostly in the tropical areas of Indonesia and West Indies. The world annual production of nutmeg and mace is around 12000 tonnes and 2000 tonnes, respectively (Krishnamoorthy and Rema, 2001). A native of the Moluccas (The Banda Islands of East Indonesia), nutmeg is presently cultivated in several countries such as Grenada, Malaysia, Papua New Guinea, Sri Lanka, Fiji, some Caribbean Islands, Africa and China including India. Of late, Brazil also started its cultivation. The Indonesian nutmeg known as East Indian nutmeg shares 75% and Grenadian known as West Indian nutmeg shares 25% of world market and they are major suppliers in the world. The East Indian nutmeg is highly aromatic which is preferred by the USA. West Indian type is of mild flavour and is preferred in Europe. The major importers are USA, Canada, Japan and European countries. In USA, the oil is generally preferred whereas the Europeans consume it as whole spice.

Introduction

The health and wellness of human being is largely dictated by the consumption of nutritious foods. Understanding the role of foods in maintaining health and cure of diseases has its roots in the ancient Hippocratic and Vedic texts as well as in the canons of Traditional Chinese Medicine (Sharma et al., 2012). Presently, the transition from a traditional to modern lifestyle, consumption of diets rich in fat and calories combined with a high level of mental stress has been the major cause of lifestyle related diseases like coronary heart disease, obesity, diabetes, cancer and hypertension (Moczara et al., 2012; Sharma et al., 2018). Various studies have linked foods as helpful in combating a number of such degenerative diseases (Sharma, 2015).Therefore, the tenet "Let food be thy medicine and medicine be thy food", quoted by Hippocrates about 2,500 years ago is receiving overwhelming interest. There are number of scientific reports emphasizing the importance of consuming biologically active ingredients present in fruits, vegetables, whole grains and legumes to reduce the risk of chronic diseases (Hasler 2002; Das et al., 2011; Sharma and Sharma 2016). Such biologically active ingredients are now popularly known as neutraceuticals. Whereas, the functional foods are the foods that resemble traditional foods but possess demonstrated physiological benefits. In some countries, however, functional foods and nutraceuticals are used interchangeably. Regardless, the main focus of such products is to improve health and reduce disease risk through prevention. The main difference of this category with pharmaceuticals is that they are multi-targeted mixtures and present at low concentration while pharmaceuticals are uni-targeted pure compounds with high dose use. Hence, an overview on the concept of nutraceutical and functional foods, their classification, development and regulations is summarized in this article.

Abstract

Quinoa is a pseudo-cereal which belongs to family Chenopodiaceae. Quinoa can act as highly potential crop for areas where ecological conditions do not support other food crops because of its rusticity, tolerance to frost, salinity, drought and ability to grow in marginal soils. Recently, much attention is focused on quinoa for people with celiac disease and allergic to gluten. Quinoa contains high-quality protein, complete with all essential amino acids and is a good source of carbohydrates, lipids, vitamin C, vitamin E (natural antioxidants) and adequate amount of important micronutrients such as minerals. Carbohydrates of quinoa possess excellentfreeze-thaw stability and can be used as thickener in frozen foods.

Quinoa also consists of bioactive components such as phytosterols, squalene, fagopyritols and polyphenols which act as powerful anti-oxidants in-vitro and thus couldprevent degenerative diseases such as coronary heart disease, atherosclerosis and Alzheimer's disease. Fibre accounts for 6% of the grains total weight, and quinoa intake therefore promotes intestinal transit, regulates cholesterol, stimulates the development of beneficial bacterial flora and helps prevent colon cancer. The quinoa grain can be used to combat liver disease, angina and cystitis. The radical scavenging ability and Angiotensin I converting enzyme (ACE) inhibition activity of quinoa is higher than that of amaranth, rice and wheat. Recent studies have identified significant amounts of ecdysteroids, kaempferol, quercetin, two phytoestrogen - daidzein and cenistema in quinoa. Ethanolic extract of quinoa was observed to have Antioxidant and antihypertensive activity.

1. Introduction

Buckwheat is one of the most important life supporting nutritious crops, which has come as a secondary crop in many countries and has now attained its position in the agriculture of many countries where cereals form the stable food for the people. Though the crop is not a cereal, the seeds themselves can bring the name ‘pseudocereal’ due to their similar usage as cereal grains. There are many species of buckwheat in the world, of which mainly nine species have agricultural value (Krkoskova and Mrazova, 2005). Generally, the genus Fagopyrum in the family Polygonaceae includes two buckwheat species used for food around the world: common buckwheat (F. esculentum Moench), which is almost grown on all continents, and tartary buckwheat (F. tataricum (L.) Gaertn), which originated in eastern Tibet or northwestern Yunnan in China and is grown only in Asia, Europe, and North America (Bonafaccia et al., 2003; Tsuji and Ohnishi, 2001).

Buckwheat is grown throughout a large area as a crop that fits the farming system on marginal and fairly unproductive land. It is used as a subsistence crop in many of the more mountainous areas where it is often grown with barley at the higher altitudes. Tartary buckwheat, because of its frost tolerance, is generally grown at the higher altitudes whereas common buckwheat is grown at the lower altitudes. In many areas the trend is for replacement of common buckwheat, which has lower yielding ability and lacks frost tolerance, with finger millet or other crops.

Abstract

The aim is to review the potential health benefits of minor millet. There is in need to identify newer sources of nutraceuticals and other natural and nutritional materials with the desirable functional characteristics. They are an important staple food in India for people of low income groups. Minor millet is rich in several nutrients as well as non-nutrients such as phenols. Nutritionally, its importance is well recognised because of its high content of calcium (0.38%), dietary fiber (18%) and phenolic compounds (0.3-3%). Minor millets, one of the cereals are known for several health benefits including its polyphenol and dietary fiber contents. Health beneficial effects include anti-diabetic, anti-tumerogenic, atherosclerogenic effects, antioxidant and antimicrobial properties. The energy of minor millets is greater than other cereals and nearly equal to that of brown rice because the lipid content is generally higher (3 to 6%). This review deals with the nature of polyphenols and dietary fiber of minor millets and their role with respect to the health benefits associated with millet.

Introduction

While Indian agriculture has evolved to provide food to our ever growing population, nutrition security still remains a distant dream. Fruits an important component of a healthy diet, are rich source of nutraceuticals. Such health components comprising of flavonoides, carotenoides, vitamins, anthocyanins and other polyphenolics provide health benefits of disease prevention through antioxidant activity and reduced disease risks. Of late there has been an explosion of consumer interest in the health enhancing role of physiologically-active specific food components commonly referred to as nutraceuticals and functional foods.

The term ‘nutraceutical’ was first coined by an American doctor Stephen DeFelice in the 1990s. Today, healthcare market is flooded with different new nutraceutical related terminologies like, cosmeceuticals, biopharmaceuticals, herbaceuticals, ayuraceuticals, dermaceuticals, nutri-cosmetics etc. A review of 200 epidemiological studies showed that cancer risk in people consuming diets high in fruits was only one-half that in those consuming few of these foods. Increased acceptance and use of nutraceuticals and functional foods in the western world has resulted in increased export of such commodities from these countries. World-wide market for nutraceuticals and medicinal plant products today has surpassed US $ 15 billion with the top markets being United States (US $ 3 billion), Europe (US$ 2.4 billion), Japan (US$ 2.7 billion) and Asia (US$ 2.7 billion). It is increasing at the rate of 10% per annum. USA holds a significant share (35%) in world nutraceutical market followed by Japan (25%). As per the US estimates, the market for natural food colorants is estimated at US $ 500 million out of which anthocyanin and lutein together account for US $ 200 millions. Other large, emerging international markets in south and southeast Asia and mid-east gulf countries include UAE, Qatar, Oman and Kuwait. At present nutraceuticals and food supplement based functional foods account for trade worth US$ 170 billions and India’s share in this market is less than one per cent.

Introduction

The primary role of the diet is to provide enough nutrients to meet metabolic requirements while giving the consumer a feeling of satisfaction and well being. Beyond meeting nutrient needs, diet may modulate various functions in the body and may play detrimental or beneficial roles in some diseases. Now a days concept in nutrition is expanding from the past emphasis on survival, hunger satisfaction and preventing adverse effects to an emphasis on the use of foods to promote a state of well being and better health and to help reduce risk of diseases.

In recent years, the words like functional foods, nutraceuticals, phytochemicals are frequently used/found in media. It is important to understand these words and understand their functions in health care.

Abstract

Wild plants have a great role in the lives of tribal peoples living in and around the world by way of providing products for both food and medicine. Such herbal plants are the core of research, which can solve several health issues as well as nutritional supplements. Keeping on the view we have presented a summary of medicinal plants used as nutraceuticals collected from various regions of India. This communication describes 35 herbal plants used as a medicine against different diseases as well as their nutritional applicability.

9.1. Introduction
The three basic need for human survival are- food, clothing and shelter. The requirement of food comes first. Human are omnivorous. They eat mainly natural foods. Before 5000 years ago, cereals were the main food for all civilization and then the complexity of life began to make appearing with the advent of industrialization, flourishing of industry and commerce. Unpolished grains were utilised at first, but in contemporary civilisation, we have begun to prepare them, which results in the loss of essential nutrients. The intake of meats, processed meals, and sugary goods has grown while the general intake of cereals has decreased. People now lack vital nutrients as a result of the departure from natural diets. People began to realise a few years ago that health is a significant concern in addition to flavour, convenience, and quality value. They have thus begun taking nutritional vitamin supplements to make up for the nutrients lost from processed meals. People are increasingly opting for natural nutraceuticals in capsules and tablets, a trend known as medicalization in nutrition, instead of relying on natural food items. Hippocrates emphasized the connection between food and medicine, stating that healthy foods has a strong therapeutic advantages. The ancient Indian medical system known as Ayurveda places a strong focus on the functioning of diet and nutraceuticals in both health and illness.
9.2. What are Nutraceuticals
Stephen De Felice, the founder and chief executive of the Foundation for Innovation in Medicine (FIM), first used the term “nutraceuticals” in 1989 to refer to the broad category of medicines and nutrition. Nutraceuticals are foods or dietary components that not only offer nourishment and energy but also significantly contribute to regulating and preserving the regular physiological processes that keep people healthy. Nutraceuticals included processed meals such as cereal-grains, soups or stews, genetically engineered foodstuffs, herbal items, nutritional supplements, and extracted nutrients. People are increasingly concerned about their healthy wellbeing these days. However, these include a hectic, sedentary lifestyle, unhealthy eating patterns, body image issues, and being afflicted by a number of illnesses. These are the factors driving the global nutraceutical market’s expansion and generating a lot of interest. Numerous health issues of the century, including cancer, type 2 diabetes, heart disease, inflammation, oxidative stress, constipation, and more, can be fought off with the use of these nutraceuticals. Overall, nutraceuticals bring an entirely novel phase in medical science and assist the food companies to promote more creative research strategies. (Dudeja and Gupta, 2017)).

Introduction Rapid increase in world population in last few decades has challenged the food producing sector (Agriculture, poultry, dairying and aquaculture) massively to meet the global food demand. The population is expected to be 9.9 billion by 2050 which means the food producing sector have to increase production by 60% further more than the current production (FAO, 2020). According to FAO (2016) approximately 17% animal protein and 7% total protein consumed by humans were provided by fish. Accordingly, per capita fish consumption was gradually increasing worldwide at 1.5% rate annually from 9.0 kg in 1961 to 20.5 kg in 2017 (FAO, 2018; Fajardo et al., 2022). Aquaculture which accounts for 47% of total fish production is expected to overtake capture fisheries by 2024 and reach 52% by 2029 (FAO, 2020).

Introduction

Citrus fruits are acidic, exotic fruits with juicy, bitter, fruit segments inside. Citrus fruits commonly originated in tropical and sub-tropical regions of the world. They have long been valued as part of a nutritious and tasty diet. The f lavours provided by citrus are among the most preferred in the world, and it is increasingly evident that citrus not only tastes good, but is also good for people. Citrus fruits have certain therapeutic properties such as antitumor, anti-inflammatory and anticancer, due to phytovitamins and nutrients present in them.

Bio-active compounds having beneficial health effect on human beings from terrestrial and marine sources are considered as “Nutraceuticals”. Nutraceuticals from marine origin are proved to have wide range of therapeutic effects viz., anti-obesity, immune enhancement, natural antioxidant, cardio protective, anti-diabetic, anti-inflammatory effects. These natural products do not have any side effects contradictory to many medicines available today, hence have attracted global market. Microencapsulation technique has been considered as one of the unique methods to encapsulate the bio-active compounds for target delivery. Importance and application of nutraceuticals from marine origin are highlighted.

Introduction

World over in the recent past, research in nutraceuticals has shown continuous growth and the progressive approach is aimed at identifying the potential nutraceutical compounds which are having health benefits in human beings. Awareness among the people is the prime reason for the growing demand for nutraceuticals.Today people are more aware about the nutrition and related health problems. Recently, researchers across the globe are exploring the possibilities to extract and isolate bio-active compounds from both terrestrial and marine sources.

1. Introduction

In this era of genomics, proteomics and metabolomics the challenge in nutritional science is to clarify human nutrient requirements and design nutritional strategies to promote health and functional longevity. Our ancient Indian belief that ‘we are what we ate’ and our future health as individuals may well depend upon what we eat today. Plant-based dietary antioxidants are believed to have an important role in the maintenance of human health because our endogenous antioxidants provide insufficient protection against the constant and unavoidable challenge of reactive oxygen species (ROS). We have various endogenous defense chemicals but they are inadequate to prevent oxidative damage that makes human system prone to various degenerative diseases. Hence, it is necessary for increased intake of dietary nutraceuticals that may help maintain the balance between oxidants and antioxidants, slow age-related changes, and prevent onset of degenerative diseases.

Introduction

Foods and nutrients play a vital role in normal functioning of the body. They are helpful in maintaining the health of the individual and in reducing the risk of various diseases. Nutraceuticals and functional foods are broad terms describing “a food (or part of a food) that provides medical or health benefits, including the prevention and/or treatment of a disease”. Nutraceuticals hold promise in clinical therapy as they have the potential to significantly reduce the risk of side effects associated with chemotherapy along with reducing the global health care cost. Food provides not only essential nutrients needed for life but also other bioactive compounds for health promotion and disease prevention. Consumption of fruit and vegetables, as well as grains, has been strongly associated with reduced risk of cardiovascular disease, cancer, diabetes, Alzheimer disease, cataracts, and age-related functional decline. A change in dietary behavior such as increasing consumption of fruit, vegetables, and grains is a practical strategy for significantly reducing the incidence of chronic diseases.

Functional foods that contain significant amounts of bioactive components may provide desirable health benefits beyond basic nutrition and play important roles in the prevention of chronic diseases. The key question is whether a purified phytochemical has the same health benefit as does the whole food or mixture of foods in which the phytochemical is present. Technological progress in manipulating plant metabolism and metabolites, combined with the explosive growth of the “functional food” industry has led to many attempts to enhance the concentration of these health-promoting compounds in specific plant-based foods . “Functional foods” are foods that, by virtue of physiologically active components, provide a health benefit beyond basic nutrition”. Functional/medicinal food is a category of botanical therapeutic available at the grocery store, which can be decrypted as “food engineered or supplemented to provide health benefits”. Thus, the future of plant-based functional foods seems bright and, as a result, grocery and drug stores might eventually look very similar. Optimization of composition of fruits and vegetables would be a very cost-effective method of disease prevention, since diet-induced health improvements would not carry any added costs for the health sector.

Several centuries ago, Father of medicine Hippocrates, has said “Let food be your medicine”. Our traditional therapies or alternative medicine effectively integrated this concept and include herbal remedies, nutritional interventions like vitamins/minerals supplementation specialized diets etc, and other techniques such as acupuncture, relaxation regimens, and homeopathic medicines. While, in modern medical science medicines are used to cure diseases which may have some inherited side effects. From the final decade of the last century, a renewed interest was seen in traditional therapies and people are thinking of integrated medicine with a focus on prevention of disease rather than its cure. In this context many terms like “dietary supplements”, “nutraceuticals” and “functional foods” were frequently used to address this issue. The term “nutraceutical” was coined from “nutrition” and “pharmaceutical” in 1989 by Stephen DeFelice, MD, founder and chairman of the Foundation for Innovation in Medicine (FIM). Nutraceutical can be defined as, “a food or part of a food, that provides health benefits, including the prevention and treatment of a disease.” However, the term nutraceutical as commonly used in marketing has no regulatory definition. There is confusion between the closely related terms nutraceuticals, functional food and dietary supplement. Kalra (2003) differentiated between these terms as: Functional food provides the body with the required amount of vitamins, fats, proteins, carbohydrates, etc, needed for its healthy survival. When functional food aids in the prevention and treatment of disease(s) and disorder(s) other than anemia, it is called a nutraceutical.

SYNOPSIS

There is an increasing awareness about quality of food among consumers all over the world. Organically produced food is considered to be nutritionally superior, but the available information is not conclusive.

Management system adopted for fruit trees are quite different, especially with regard to nutrient than that adopted for field crops. The shift in management system could be commenced 3-4 years after planting depending on the tree size. Nutrients are required for flowering and fruiting while at the same time trees are allowed to grow and maintain sufficient vigour for producing high yields in following years. To maintain productivity of trees in long run and maintain the sustainability of tree production capacity, application of nutrient should be based on actual requirement and availability of nutrient in the soil. Application of plant nutrients economically at correct time with right amounts in a way that nutrients could be taken up by plants efficiently with minimum losses. The purpose of assessment of nutrient requirement of fruit trees is to keep mineral nutrient levels in the tree with in the desired range to have the growth and development effects and fruiting of trees as desired.

The most important thing in nutrient management for bearing trees is to analyze the importance of timing of nutrient application in relation to tree phenology or growth cycle.

Concept of nutrient availability: The ions in the soil solution are available to plant provided they can reach an active root or it can reach them. The concentration of ions in the soil solution at any given moment is however; usually low, except immediately after the application of water soluble fertilizers.

Most of the nutrients are taken up by the plant in the form of cations which are positively charged. Available cations either in the soil solution or held against leaching by negatively charged clay or humus particles are easily taken up by the plants. Other plant nutrients notably phosphorus, boron and molybdenum are taken up by the plant as anions which are negatively charged. The concentration of anions in the soil solution is usually low because they become converted to new less soluble forms e.g., soluble phosphate ions forms less soluble iron or aluminium phosphates. Minerals upon weathering and organic matter upon mineralization release nutrient ions.

Physical factors

However, much readily available nutrients a soil may contain various physical features of the soil make it impossible for the plant roots to absorb it. It then becomes positionally unavailable. These features include hard pans, undesirable soil structures, presence of hard clods, dry soil horizons and water logged situation.

Low soil cation exchange capacity leads to less retention of calcium, magnesium, potassium, copper and zinc.

1. Introduction
Aquaculture has emerged as one of the fastest-growing food production sectors worldwide, a trend driven by several factors, including the rising global demand for seafood, the depletion of wild fish stocks, and the search for sustainable protein sources. As the human population continues to grow and dietary preferences shift towards healthier, protein-rich food options, aquaculture plays a pivotal role in addressing food security. However, the expansion of aquaculture also brings forth significant challenges, particularly in the efficient use of resources, including feed. One of the primary challenges for the aquaculture industry is ensuring that fish and other aquatic organisms receive optimal nutrition through formulated feeds. Aquafeeds are typically designed to provide a balanced mix of proteins, lipids, carbohydrates, vitamins, and minerals necessary for the growth, health, and reproduction of farmed species. However, not all nutrients in these feeds are equally digestible or absorbable by the animals. The efficiency with which nutrients are utilized depends largely on their bioavailability—a term that refers to the proportion of ingested nutrients that are available for absorption and utilization by the body.
1.1 Defining Nutrient Bioavailability in Aquafeeds
In aquaculture nutrition, nutrient bioavailability is a crucial determinant of overall feed efficiency. It is defined as the fraction of a nutrient that, after ingestion, becomes available for utilization in physiological processes such as growth, tissue repair, metabolism, and reproduction. In practice, this means that bioavailable nutrients must first be digested in the gastrointestinal tract, absorbed through the intestinal walls, transported to various tissues, and