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There are many types of intellectual property and its type varies from country to country. The most common types are patents, copyrights, trademarks, design and trade secrets. Intellectual property is an intangible creation of the human intellect and this intangible nature of intellectual property faces problems in comparison of traditional property like land or goods. Unlike traditional property, intellectual property is not dividable therefore a number of people can consume an intellectual good without its consumption. In addition, investments in intellectual goods suffer from appropriation problems, for instance Landowners can surround their land with a robust fence and hire armed guards to protect it, but creators of intellectual property cannot do that to stop their first buyer from replicating it and selling it at a lower price.

The key genetic parameters available with the animal breeder to attain improvement are heritability, repeatability and genetic correlation. This chapter will mainly deal with the theoretical considerations of these parameters.

The goal of an animal breeder is to bring about permanent improvement in different economic traits, either individually (univariate) or simultaneously in multiple traits (multitrait). The phenotypic value available from the animal is a combination of genotypic value and environmental deviation. By permanent improvement in a trait, we mean the improvement in genotypic value, which could be carried over to future generations. The environmental deviations are spatially and temporally specific, and thus will not be the same over generations. The genotypic value, itself is made up of additive effect, dominance deviation and interaction deviation. The additive effect is a value of genes (the sum of the average effect of genes) and hence is more important for the breeder as only the genes are passed on to the next generation.

Molecular biology is a branch of science that deals with understanding the biological activities at the molecular level. Molecular biologists are involved in understanding the concepts behind various intra and intercellular interaction of molecules, contributing to the knowledge about interrelationship of DNA, RNA and protein synthesis, i.e., how genes are transcribed into RNAs and how RNA is translated into protein, the phenomenon which is commonly known as “Central Dogma”stated by Francis Crick in 1956.

“The central dogma of molecular biology deals with the detailed residue-by-residue transfer of sequential information. It states that such information cannot be transferred back from protein to either protein or nucleic acid”-Francis Crick.

Matrix is a rectangular array of numbers arranged in rows and columns. The order of a matrix is written as r x c, where r is the no. of rows and c is the no. of columns. The numbers included in a matrix are called elements of the matrix. The name of the matrix is denoted by an uppercase English alphabet.

Strategic partnerships and productive outreach play a crucial role for new technologies to successfully reach the market, drive growth, and strengthen a country’s global competitiveness, Outreach programs have various benefits, ranging from technology transfer awareness, communication of stakeholders, industry, government, to academy partnership promotions. These efforts help in establishing connections, communicating opportunities, and encouraging active engagement from key stakeholders. Outreach activities can be performed under two broad categories:
1. Written communication includes all communication which can be viewed, shared, or made accessible for a set of people in a passive manner. This includes reports, newsletters, guidance, and online content which provide insights of worth for stakeholders.
2. Human outreach includes all direct communication like c face-to-face or verbal form communication it included conferences, conventions, workshops, seminars and personal communication with industry leaders.
The type of outreach creates stronger, more personal connections. An effective outreach strategy usually combines both human and written outreach efforts. By following this strategy TTOs can expand and strengthen partnerships, and make it easier for research-led innovations to get transition from lab to market more effectively. This chapter explores key outreach models, strategic networking approaches, and proven practices for building impactful partnerships in technology transfer.

8.1 Key legal statutes and regulatory foundations
Various policy measures were also undertaken by the Government of India in due course of time. The Government of India enacted four science policies after gaining independence, i.e. Scientific Policy Resolution (1958), Technology Policy Statement (1983), Science and Technology Policy (2003) and Science Technology and Innovation Policy (2013). The 1983 Technology Policy Statement possessed a simple goal of creating indigenous technology and boosting efficient absorption and adaptation of imported technologies suited to the nation’s priorities and. The Technology Policy Statement of 1983 was followed up through the establishment of the Technology Information Forecasting and Assessment Council (TIFAC), an autonomous organization entirely owned by the Government of India under the Department of Science and Technology during 1988. TIFAC also offers some funding and supports development and commercialization of technologies through the home-grown technology scheme, among its other operations. The Technology Development Board Act (1995) was also a significant policy move of the government in the same direction. Also in recent times, the Government of India also unveiled its own National IPR Policy 2016 with the motto cum slogan “Creative India, Innovative India”. In addition, the policy is aligned to a number of other schemes of the Indian Government like “Make in India”, “Atal Innovation Mission”, “Start-Up India” and “Stand-Up India”, all aimed at encouraging creativity, innovation and entrepreneurship in the nation.

13.1 Challenges in the technology transfer process
Technology transfer (TT) is more complex and involves the complex interrelationships between universities, research institutes, the private sector, the state, and society. Though TT is all about translating research findings into purposeful solutions that can support the economy and society, it is not a linear process. The challenges can be described as legal, institutional, cultural, financial, policy, and human resource. All this is accompanied by bottlenecks that inhibit or decelerate the diffusion of promising technologies.
13.1.1 Legal and intellectual property challenges
The vital component of technology transfer is the proper management of intellectual property (IP), which is often the most challenging aspect.
• Ambiguities in IP ownership: During multi-institutional or shared funder research, ownership is quite controversial. As an example, when a government lab and a university collaborate on the project, there is ambiguity as to who would have the ultimate licensing authority over the technology: the university, the lab, or the funding agency. This kind of fight hinders commercialisation and scares off industry partners.
• Lengthy patent filing and prosecution timelines: In several jurisdictions, the filings, examination, and granting of a patent may take between three and five years or more. Such delay is not compatible with the rapid cycle of invention in other fields such as ICT or biotechnology, where patent claims may become invalid before they are granted.
• High costs of IP protection: International direct patenting, like under the Patent Cooperation Treaty (PCT), is costly and involves legal services, fees, and upkeep costs. These costs are excessively high, which cannot be easily compensated by universities and startups, and where technologies are not secured or limited to local markets.

3.1    Competitive and Collaborative Research
    
3.2    The Strategy to Protecting Plants : Plant Variety Protection Act
    
3.3    IPR Issues in Biotechnological Patents Haldi, Neem and Basmati Rice
    
3.4    Patent Litigation

The cornea is the anterior transparent part of the fibrous tunic of the globe which has both mechanical and optical function. It functions to support the intraocular contents and transmit and refract light. Histologically, the cornea is composed of an outer stratified squamous corneal epithelium and its basement membrane, an underlying collagenous stroma, a thin acellular membrane, and an inner monolayer of cells, the corneal endothelium. In dogs, the central cornea is thinner than the peripheral cornea, whereas regional differences in thickness may not exist in cats. The active pumping mechanism of corneal endothelium and the barrier function of anterior epithelium keep the cornea in a state of relative dehydration. Compromise of either of these mechanisms will allow corneal edema to develop, with a concomitant increase in corneal thickness. Corneal ulceration is one of the most common ophthalmic disorders in veterinary medicine. Corneal ulcers are classified based on depth and ease of healing. There are several phases during the corneal epithelial wound healing process, including a lag phase where cells alter their metabolic status; a migration phase to cover the bare surface; a proliferation phase and a differentiation phase, where cells stratify and re-establish multiple layers of distinct cells. Methods of surgical treatment for canine corneal ulcers include temporary tarsorrhaphy, third eyelid flap, conjunctival pedicle graft, tissue adhesive, corneo-scleral graft and transplantation of natural or synthetic material.

In some developing countries, milk from horses (Equus caballus) and donkeys (Equus asinus) is an essential food for poor farmers. Generally, horses are more commonly used for dairy purposes in cool areas and donkeys in dry semi-arid regions. Milking equines is time-consuming and has to be repeated five or six times a day. In addition, an equine will not release milk unless it is stimulated by the presence of its foal. Mare’s milk is commonly consumed in the steppe areas of Central Asia, where a traditional lactic-alcoholic beverage called koumiss is produced through fermentation. Horse milk is also an important source of animal protein for pastoralists in Mongolia. The consumption of donkey milk has become very marginal. In some African communities, donkey milk is consumed for medical purposes.

Equus is a genus of mammals in the family Equidae, which includes horses, asses, and zebras. Within the Equidae, Equus is the only recognized existing genus, comprising seven living species. Like Equidae more broadly, Equus has numerous extinct species recognized only from fossils. Equines are odd-toed ungulates with slender legs, long heads, relatively long necks, manes (erect in most subspecies), and long tails. All species are herbivorous, and mostly grazers, with simpler digestive systems than ruminants but able to subsist on lower-quality vegetation. The chromosome number of a horse is 64 (2n).

Introduction

‘IP’ refers to unique, value-adding creations of the human intellect that results from human ingenuity, creativity and inventiveness. An IP right is thus a legal right, which is based on the relevant national law encompassing that particular type of intellectual property right. Such a legal right comes into existence only when the requirements of the relevant IP law are met and, if required; it is granted or registered after following the prescribed procedure under that law. All countries around the world have a national legal system of intellectual property rights which has developed over varying periods of time during the last 150 years or so. It has enabled the grant of property-like rights over such new knowledge and creative expression of mankind, which has made it possible to harness the commercial value of the outputs of human inventiveness and creativity. This is usually done by its orderly use, exchange or sharing it amongst various types of business partners in a complex network of strategic relationships that generally work harmoniously during the new product development process for creating and marketing new and improved goods and services in domestic and export markets.

IPR is a tool for Innovation and reward for it. Innovations are concerned with the commercialization of new ideas; in contrast, an ‘invention’ may not be directly associated with commercialization. As such, innovation may be seen as a process of interaction and feedback during the various stages of the new product development process. An invention is considered as the generation of a new idea or knowledge, which aims to solve a specific technical problem. Inventions could relate to products or processes and are characteristically protected by trade secrets, utility models/petty patents or patents. Utility models/petty patents or patents are granted/registered under the relevant national/regional law by the relevant national or regional patent office. As not all inventions are commercialized, so it is clear that not all inventions result in innovations.

20th Livestock Census of India

India has highest cattle population (192.49 million), buffalo population (109.85), in the world producing 24% is the highest milk yield (221.1 million tons in the year 2021-2022, and per capita availability was 444 gm/day) in the world (Source NDDB). India produces 43% of world buffalo meat production. Unfortunately, 80% cattle and 70% buffaloes are non-descriptive and yield very low amount of milk.

After independence Indian Council of Agricultural Research (ICAR) has developed serval projects and plans for research and characterization of livestock species all over the country. Our country holds enormous genetic biodiversity in our domestic animals, result in increasing number of registered breeds in every decade. Breed registration Committee on its online meeting held on 5th December, 2023 approved registration of eight new breeds of livestock. This includes Aravali Chicken (Gujarat) Andamani Duck (Andaman and Nicobar Islands), Anjori Goat (Chhattisgarh), Andamani Goat (Andaman and Nicobar Islands), Bhimthadi Horse (Maharashtra), Andamani Pig (Andaman and Nicobar Islands), Macherla Sheep (Andhra Pradesh), Frieswal Cattle (Uttar Pradesh and Uttarakhand). Endangered, critical and vulnerable breeds of livestock also have been identified by ICAR which need more scientific research and multiplication breed.

It is emphasizing the systematic approach required for the successful planning and funding of projects:
Components of Project Formulation
1. Needs Analysis: Identifying and defining the needs that the project intends to address, typically involving stakeholder consultation and market analysis. This process involves systematically gathering and analyzing data about a community, a group, or a market to identify both the current conditions and the gaps between these conditions and desired outcomes. Effective needs assessment aids in designing projects that are relevant, targeted, and likely to produce significant impact. Here’s a more detailed exploration of how needs assessment is integral to project formulation:
Key Steps in Conducting a Needs Assessment
• Stakeholder Identification: Early in the project formulation, identify all relevant stakeholders, including direct beneficiaries, community leaders, funders, and other affected parties. Understanding who will be impacted by the project helps in targeting the needs assessment process more effectively.
• Data Collection: Utilize various methods such as surveys, interviews, focus groups, and field observations to gather comprehensive data about the current state and deficiencies experienced by stakeholders. This might involve looking at socioeconomic data, environmental conditions, or specific community challenges.
• Gap Analysis: Analyze the data to identify gaps between the current state and the desired outcomes. This analysis helps pinpoint the specific areas where interventions are needed.formulation: 

ABSTRACT

The law of intellectual property has assumed utmost importance the World over, in the recent past and it is being considered as one of the most important subjects of law in view of its implications on economic, social and cultural realms. The term “intellectual property” has come to be internationally recognized as covering, patents, industrial designs, copyrights, trademarks, know-how and confidential information or trade secrets. This paper presents an overview on nature and scope of these elements of IPR.

Artificial Intelligence (AI) is a discipline of computer science that now days affecting evary aspect of day to day life. It has the potential to greatly improve animal breeding programs in India by providing more accurate and efficient selection methods. Some of the avenues and possibilities of using AI in animal breeding in India includes Predictive analytics: AI can be used to develop optimization models that take into account a variety of factors, such as genetics, phenotypic traits, and environmental conditions, to identify the best breeding strategies. AI can be used to analyze large amounts of data on animal genetics, phenotypic traits, and environmental factors to predict the likelihood of an animal producing offspring with desired traits. This can help breeders make more informed decisions about which animals to be selected for breeding. AI algorithms can be trained to accurately identify diseases in animals by analyzing imaging data, such as X-rays and MRI scans, as well as blood and tissue samples which in turn facilitate veterinarians to make more accurate diagnoses, improving treatment outcomes. AI can also improved feed efficiency by analyzing the feed consumption and nutrient utilization data to identify patterns and trends that can be further utilized to improve feed efficiency, reduced feed costs and increased production efficiency.

Introduction

Raising milk and meat production are long-standing global issues. Researchers are learning that present breeding efforts won't be sufficient to meet anticipated future food demands given the current climate scenario. The animals that influence the overall yield of the field must be screened as soon as possible. In order to build more successful modern breeding programmes, high-throughput phenotyping is currently being included into conventional breeding operations. Despite the public accessibility of their genetic information online, there is still a lack of phenotypic data on the genomes of various animal breeds because environmental factors make it more difficult to define phenotypes and increase the likelihood of measurement error (Rahaman et al., 2015). Genomic selection (GS) is a strategy that predicts the genomic estimated breeding values of lines in a breeding population using information from genome-wide markers (Meuwissen et al., 2001). When compared to other conventional methods like marker-assisted selection (MAS), genomic selection has some inherent advantages. These include boosting genetic gain by reducing breeding cycles and acquiring minor effect loci based on markers dispersed throughout the entire target genome. Reliable phenotypes and genotyping are both necessary for the training of accurate prediction models for genomic selection. Phenotyping is regarded as a significant factor restricting genetic improvements in animal breeding due to high labour and time expenditures. Traditional approaches of phenotyping are prohibitively expensive, time-consuming, and slow.

True/False

Q.1.    The purpose of most medical research is to identify the causes of disease and search out the ways to prevent or cure them.
Q.2.    Now a day, epidemiology has become a basic science for public health
Q.3.    The studies of diagnostics therapeutic and prognostic procedures have successfully incorporated into growing stream of “Clinical Epidemiology”.

ABSTRACT

This paper provides an account on the origin of the concepts of IP, gradual development and their culmination at the TRIPS.

Introduction

Intellectual property rights form the most prominent and ever-expanding category of rights in the 21^st Century. It differs from other proprietary rights in many respects and prevails in most articles of law, which influence our daily life. The economic significance of intellectual property rights has made it a subject of global political interest. In the broader sense, the term “intellectual property rights” connotes different categories of rights such as patents, copyrights, trademarks, designs, plant varieties, semiconductors, geographical indications, trade secrets and data exclusivity with varying scope

The analysis of chromosome behaviour at meiosis can provide valuable information about the genomic composition of both species and hybrids. The basis for this analysis is the idea that chromosomes that pair and undergo chiasma formation are homologous. Where two genomes are present, as in diploids, the expectation is that only bivalents will be observed and where there are multiple genomes, as in polyploids, two general patterns of pairing are possible. In autopolyploids, configurations of multiple chromosomes are to be expected since all the component genomes are homologous and have the possibility of pairing with each other, whereas in allopolyploids, with different genomes, bivalent formation is the expectation. Thus, meiotic analysis can provide an oversight for genome analysis to investigate genetic relationships between the species. Further, chromosomal rearrangements are correlated with pollen fertility in species and F₁ hybrids.  Observations on pollen formation, size and viability can provide useful information, as low pollen viability is often indicative of meiotic irregularities and large sized pollen can indicate the formation of unreduced gametes. In addition, the occurrence of nucleolar dominance has been recorded in many interspecific hybrids.

Introduction

Estimated breeding values (EBVs), often estimated for sires, are used in traditional animal breeding (TAB) programmes to make selections based on an animal’s performance and that of its relatives. Using, typically, the best linear unbiased projections, EBVs are calculated using attributes measured in own performance, pedigree, sib, and/or progeny evaluation schemes in specialised testing stations and/or selected farm conditions (BLUP; Henderson, 1975). One of the main time-consuming challenges for phenotypic evaluation to enable a meaningful estimation of breeding values is generation intervals of 4 to 5 years in beef cattle, more than 5 years in dairy cattle, and 2 to 2.5 years in pig breeding schemes (Schefers and Weigel, 2012). Modern breeding techniques like marker-assisted selection (MAS) and, more recently, genomic selection (GS) are based on the use of genetic DNA markers to aid in selection and breeding (Williams, 2005). The fundamental reason why MAS, that only further uses a few markers as a selection tool, hasn’t made as much progress as was initially anticipated is that finding trustworthy markers is challenging, particularly when dealing with complex traits. Only relatively few consistent markers could be identified, despite successful identification of many quantitative trait loci (QTL; Hu and Reecy, 2007)