eChapters

Introduction

In the last decade, digitalization has transformed every aspect of life and society, changing almost every area of our day-to day lives. Not just that; the rate of change that is happening is astonishing and only going to accelerate further. From the way, we work and communicate to how we organize our lives, digital tools and technologies are everywhere including the veterinary sector. Veterinarians are recognizing the need to depart “the analog island” and increasingly willing to embrace digital solutions. Undoubtedly, digitalization is crucial when it comes to boosting efficiency and quality in veterinary medicine and delivery of animal healthcare to masses across various geographies and resource poor setups. Uniquely these digital tools helps vets also to focus on the needs of patients and animal owners.

Food preservation is increasingly influenced by digital technologies associated with Industry 4.0. Ensuring food safety now requires not only microbial control but also authenticity, traceability, continuous quality monitoring and rapid decision-making. Artificial intelligence and machine learning can analyse complex datasets to predict shelf life, recognise spoilage patterns and assess risks arising during processing, storage and distribution. Internet of Things devices connect sensors across the cold chain, while blockchain supports transparent and secure traceability. Smart pH, temperature, humidity, optical and biosensors provide real-time information about product conditions. The chapter examines these technologies alongside automation while considering data quality, model validation, infrastructure, cost and industrial implementation challenges.

Quantitative heat production estimation is necessary to  know the net energy of feeds and fodders. In the case of ruminants approximately 8 per cent of the gross energy consumed is lost as methane, therefore it becomes necessary to know this important loss in terms of methane energy so as to assess the metabolisable energy of any particular feed. In human subjects, heat production studies are conducted to know the effect of planes of nutrition on basal metabolism as affected by different environmental conditions.

In the important laboratories of world, heat production and methane production studies were conducted by respiration chamber (open circuit and closed circuit), since in our country respiration chamber has been installed at IVRI, Izatnagar, Bareilly (U.P.) India, therefore, this technique is mentioned in brief in this chapter. Indirect calorimetry involving the use of face mask and Douglas bag is followed at present in our country at NDRI, Karnal (India) so as to study the basal metabolic rate (BMR), heat production in human subjects and animals, Krishna (1973). Some laboratories in the country are interested to study respiratory quotient at different levels of feeding in human subjects and animals. The methods of estimation of RQ (respiratory quotient) is expressed in detail in this chapter.

Efforts to Mitigate Natural Disaster at National and Global Level

What is A ‘Disaster’?

It as ‘an event that has occurred unexpectedly with destructive consequences’ - (UNOCHA 2005). 
It as ‘a calamitous event resulting in loss of life, great human suffering and distress, and large scale material damage’ - (IFRC2005).
None of the international agencies take animals into account in their definitions

Health care is an important way of making sure that rabbits stay productive. Every rabbit keeper should know how to recognize and, if possible, prevent and cure illnesses which can affect rabbits.

It is always better to prevent disease incidence than to let animals get ill and then try to treat them. Allowing rabbits to get sick is expensive for several reasons, sick animals stops growing and reproducing so money is lost with this decrease in production, some disease results in the death of rabbits, replacing the dead rabbits is expensive , treatment for the ill rabbits is usually expensive.

Climate change in particular global warming affect the health of the animals both directly and indirectly. Direct effects include temperature associated diseases like heat stroke and death and morbidity of animals during extreme weather conditions. Indirect effects include those deriving from attempt to adapt to changing environment or influence of climate on microbial populations, distribution of vector borne diseases, host resistance to infectious agents, feed and water shortages or food borne diseases. Among infectious diseases vector borne diseases and diseases caused by agents who have a stage in the environment are more likely to be affected than other diseases. The assessment of impact of climate change on animal diseases is challenging because there are several factors affecting the disease dynamics. But once the risk of potential diseases and their transmission routes are identified, the disease forecasts can be generated and control measures can be implemented to reduce the risk of such diseases.

DISEASES OF RABBITS

The Disease Occurrence in rabbit colony is minimal if good sanitation and hygiene measures are followed.

Diseases are caused by Bacteria, Viral, Parasitic and managemental.

Bacterial Disease

Pasteurellosis → similar to Haemorrahgic septicaemia

Organism → Pasterurella multocida

Affects respiratory system with difficulty in breathing. Temperature 103 ° F Occulonasal discharge observed.

Lab → Blood smear shows bipolar organisms by Giemsa stain.

Treatment → Sulpha drugs, long acting tetracyclines.

Human life on the earth has been intertwined with the fabric of crops and livestock for its sustenance, since time immemorial, for food and protection against the vagaries of nature. When agricultural and livestock production systems began to change in the 1950s, from traditional extensive systems to semi-intensive and intensive production systems, diseases of rural farm enterprises became challenging. Especially, the emerging diseases in livestock continued to demand more and more investments for ensuring food safety and security. Despite significant progress made in the recent past in reducing the prevalence of animal diseases, there is still an increasing concern over the losses associated with diseases of economic importance that result in production inefficiency. The scientific foundation for the discipline of animal health economics was laid by Morris (1969) and further steps were taken by Ellis (1972) to economically evaluate the Swine Fever eradication programme in Great Britain using cost-benefit analysis, Martin Hugh-Jones (1975) to specialize in GIS to model diseases and assessed the economic impact on production by infectious diseases, James and Ellis (1978) to use the same tool for FMD control programme, Renkema and Stelwagen (1979) to evaluate the replacement rates in dairy herds, Renkema (1980) to analyze the economic aspects of diseases in animals, Ellis and Putt (1981) to suggest the epidemiological and economic implications of FMD vaccination programme in Kenya, and McInerney (1983) to analyze the economics of animal diseases in dairy cattle, the multidisciplinary field of animal health economics was not amply exploited especially in developing countries to assess the extent of livestock disease losses (Ngategize and Kaneene, 1985).

Calcium is a vital mineral playing an essential role in numerous physiological processes, including bone formation, muscle contraction, nerve impulse transmission, and blood clotting. Proper calcium metabolism in animals is regulated by a complex interplay of dietary intake, hormonal control (mainly by parathyroid hormone; PTH, calcitonin, and vitamin D), and organ systems such as the kidneys, intestines, and bones. Imbalances in calcium homeostasis, whether due to dietary deficiencies, genetic predispositions, hormonal dysfunctions, or systemic diseases, can lead to a wide range of disorders affecting the skeletal system and overall health. Calcium-related disorders in animals can broadly be classified into those resulting from calcium deficiency, excess, or abnormalities in calcium regulation. Among these, skeletal manifestations are the most pronounced, as the bones act as a primary reservoir for calcium in the body. Various diseases related to calcium disorders and their nutritional management are discussed
below:
a) Rickets
Rickets is a skeletal disorder that affects young animals and birds, characterized by improper bone mineralization. This condition occurs primarily due to deficiencies in vitamin D, calcium, and phosphorus, which are essential for proper bone development. Rickets can lead to deformities, pain, and reduced growth rates, and understanding its causes, symptoms, mechanism, and nutritional management is crucial for prevention and treatment.

Common salt, or sodium chloride (NaCl), is an essential mineral that plays a critical role in the health and productivity of livestock and poultry. It is a major source of sodium (Na) and chloride (Cl), both of which are vital for maintaining osmotic balance, acid-base regulation, nerve conduction, and muscle function. However, deficiencies or excesses of common salt can lead to severe health issues, reduced productivity, and even mortality in animals. This chapter discusses common salt disorders, their causes, symptoms, and the nutritional management strategies necessary to prevent and mitigate these
problems.
Importance of common salt in animal health
1. Electrolyte balance: Sodium and chloride maintain osmotic pressure and fluid balance within the body.
2. Acid-base regulation: Sodium and chloride are crucial for maintaining acid-base homeostasis in the blood.
3. Nerve and muscle function: Sodium is essential for nerve impulse transmission and muscle contractions.
4. Digestive health: Chloride is a major component of gastric acid (hydrochloric acid), which aids in digestion.
5. Milk and egg Pproduction: Adequate salt levels are required for optimal production in dairy animals and laying poultry.

Magnesium is a vital mineral for animals, playing critical roles in enzyme activation, muscle contraction, nerve transmission, and bone development. Disorders related to magnesium imbalance can lead to severe health issues, affecting productivity, reproduction, and overall well-being. This chapter explores diseases associated with magnesium disorders in animals, their causes, symptoms, and management strategies.
Importance of magnesium in animal health
Magnesium (Mg) is involved in several physiological processes:
Activation of over 300 enzymes, including those in energy metabolism,
Regulation of muscle and nerve function,
Maintenance of normal heart rhythm,
Bone structure and calcium-phosphorus metabolism,
Magnesium disorders primarily manifest as hypomagnesemia (deficiency) or hypermagnesemia (excess), with hypomagnesemia being more common and significant.

Phosphorus is a critical mineral for animal health, playing a vital role in bone development, energy metabolism, cell signalling, and overall physiological functions. Disorders related to phosphorus imbalance, whether due to deficiency or excess, can lead to significant health issues in animals.
a) Pica
Pica is a condition characterized by the persistent ingestion of non-nutritive substances such as soil, rocks, plastic, cloth, or other inappropriate materials. While commonly observed in humans, pica is also prevalent in animals, including livestock, domestic pets, and wildlife. It is often a sign of underlying health, environmental, or nutritional issues. Understanding the causes, implications, and management of pica is crucial for animal welfare and productivity.
Causes of pica in animals
The aetiology of pica in animals is multifaceted and can be broadly categorized into nutritional, medical, behavioural, and environmental factors.

Health care and preventive hygiene in rabbits are very important for the productivity of the rabbits and economical viability of a farm.

It is always better to prevent the disease rather than to get an animal treated, which is usually quite expensive. As such it is desirable that the rabbits are checked daily. The health and ailment signs can be recognized from the following things:

Sodium (Na), potassium (K), and chloride (Cl) are essential electrolytes that play critical roles in maintaining fluid balance, acid-base homeostasis, nerve transmission, and muscle function in animals. Imbalances in these electrolytes, whether due to deficiency or excess, can lead to serious health issues that affect productivity and well-being. This chapter discusses the disorders associated
with sodium, potassium, and chloride imbalances in animals, their causes,
symptoms, and nutritional management strategies.
1. Sodium disorders
Sodium is the primary extracellular cation and is crucial for maintaining osmotic pressure, fluid balance, and nerve signal transmission.
a) Hyponatremia (Sodium deficiency)
Causes
1. Dietary deficiency: Inadequate sodium in feed or water.
2. Excessive loss: Through sweat, diarrhea, vomiting, or prolonged lactation.
3. Dilutional hyponatremia: Excessive water intake diluting sodium levels.

Sulphur (S) is a vital mineral for livestock and poultry, playing a key role in the synthesis of amino acids (methionine, cysteine), vitamins (biotin, thiamine), and other critical metabolites. While sulphur deficiencies or excesses are less common than imbalances in other minerals, they can lead to significant health and production challenges. Effective nutritional management is crucial to prevent and address sulphur-related disorders.
Importance of sulfur in livestock and poultry
Sulfur is essential for:
1. Protein synthesis: It is a component of sulfur-containing amino acids like methionine and cysteine, which are critical for growth and tissue repair.
2. Structural integrity: Sulfur contributes to the structure of keratin, essential for wool, feathers, and hooves.
3. Metabolic functions: It is involved in the synthesis of vitamins (biotin and thiamine), enzymes, and coenzymes.
4. Detoxification: Sulfates aid in detoxifying harmful substances in the liver.
Sulphur deficiency (hypo-sulfurosis)
Causes
1. Low dietary sulphur: Diets low in sulfur-containing ingredients, such as grains or poor-quality forages.
2. Imbalanced nitrogen-sulphur ratio: Excessive non-protein nitrogen (e.g., urea) in ruminants’ diets without adequate sulfur supplementation.
3. Poor feed quality: Grazing on sulfur-deficient soils or consuming sulfurdepleted feeds.

A disease is any process which disrupts an animals’s normal function. Occurrence of diseases causes heavy economic loss in terms of livestock health and production. Presence and accumulation of infectious agents in the environment lead to reduction in quality and quantity of animal products. Strategic control and eradication of economically important diseases will result in enhancing goat production in the country. Goat suffer from many diseases although the susceptibility of goats to diseases is less as compared to sheep or cattle. Goat diseases can be bacterial, viral or parasitic. Viral diseases are more common in herds and are responsible for large scale mortality at one time. With a good hygiene in the barn and if the goats are kept in a way appropriate to their species, most of the diseases can be avoided.

Much attention has not been paid for prevention and control of goat diseases since most of the goats are reared by poor people and prevention and control is generally considered uneconomical. However, this is not true, as small investment in disease prevention and control can bring enormous gains in goat productivity. Simple preventive measures like deworming and vaccination alone can save the herds from heavy mortality and can increase production considerably. Serious and early efforts on diagnosis and prevention of goat diseases are essential in order to improve the health and production. A wide range of bacterial, viral, parasitic infections, causing heavy mortality and morbidity result in huge economic loss to different goat farming systems. Metabolic and nutritional disorders in goats also affect their production performance. Metabolic disorders are of great importance in pregnant goats, especially those carrying multiple foetuses. Deficiencies of essential minerals, metabolites and amino acids below the critical level also adversely affect the production. Therefore, it is necessary to avert these imbalances (calcium, magnesium, Co, Cu, Zinc, Iodine) in the ration. Provision for extra energy and protein in late pregnancy are necessary to avoid parturient paresis due to low blood sugar and high ketones and hepatic insufficiency of glycogen. Soil- plant- animal interactions in relation to the incidence of chronic deficiency diseases of goats are often being observed.

Introduction

Disorders of the hemopoietic system in poultry can significantly impact the health and productivity of these birds. The hemopoietic system is responsible for the production of blood cells, including red blood cells, white blood cells, and platelets. Disorders within this system can lead to various health issues, including anemia, immunodeficiency, and impaired blood clotting. Some of the common disorders of hemopoietic system include:

1. Anemia: Anemia is a condition characterized by a decrease in the number of red blood cells or hemoglobin in the blood. In poultry, anemia can be caused by various factors, including nutritional deficiencies (such as iron deficiency), infectious diseases (such as avian malaria or chicken infectious anemia), and parasitic infestations (such as blood-sucking parasites like leucocytozooncaulleryi, ticks, lice and mites).

2. Avian Leukosis:Avian leucosis is a viral disease caused by avian leukosis virus (ALV). It primarily affects young birds, causing tumors in various organs, including the spleen, liver, and bursa of Fabricius. Avian leukosis can lead to immunosuppression, anemia, and increased susceptibility to secondary infections. The avian leucosis diseases include lymphoid leucosis (affecting lymphoid cells), myeloid leucosis (affecting myeloid cells), osteoptrosis, etc. and can result in immunodeficiency, increased susceptibility to infections, and other systemic symptoms. It also affects blood-forming tissues, including the bone marrow and lymphatic system, leading to an overproduction of abnormal white blood cells.

Introduction

Poultry are domesticated birds mostly reared for the purpose of meat and egg consumption as well as for their feathers. It includes chickens, quails, turkeys, waterfowls, ducks and geese. The endocrine system of poultry consists of hypothalamic-hypophyseal complex, parathyroid gland, thyroid gland, pancreatic islet cells, adrenal glands, ultimobranchial glands, endocrine cells of gut and the gonads. These endocrine organs release hormones into the bloodstream. Peptide hormones act on the surface of cells, whereas steroid hormones act on target tissues by entering in the cytoplasm or nucleus of cells. Lack of diagnosis in the case of endocrinopathies is a major cause of production loss globally. Advancement in awareness, diagnosis, treatment as well as management is critical to ensure optimal flock health. Cost-effective programs of biosecurity and vaccination are required to prevent or limit the impact of disease. Programs of emergency treatment and long-term prevention are justified for severe endocrine diseases which have a profound impact on production.

Introduction

Eye

Avian ocular apparatus includes eyeball, optic nerve, and accessary structures e.g., eyelids, lacrimal glands, and muscles etc. The eyeball is composed of three tunics namely the f ibrous (cornea and sclera), vascular (choroid, iris, ciliary body) and nervous tunic (retina). The histological structures of all these tunics are similar to mammals except the Bowman’s membrane (the basal lamina of corneal epithelium) is not distinct. Similar to the mammals, they also have three refractive media viz., aqueous humour, lens, and vitreous humour. The cornea does not refract light.

There are some important diseases and disease conditions of eye in poultry birds. The common aetiology of eye diseases in poultry birds has a wide range and includes heredity, nutritional deficiency, infections (microbial and parasitic) and managemental failure. Some of them are not seen often in the modern intensive rearing systems like the deficiency diseases while others are seen associated only with the intensive system housing of birds like the ammonia burns. The infectious diseases of only eyes, are not encountered in poultry birds. The diseases like the colibacillosis, pasteurellosis and Marek’s disease can affect eyes along with other body systems. Understanding of eye diseases of poultry birds requires basic knowledge of ophthalmic anatomy, concepts and terminology of eye associated pathological changes. The affected birds generally show ocular lesions and loss of condition due to starvation as they are unable to search for feed and water. Some conditions are reversible while others may be irreversible according to the extent of damage. Nutritional and managemental diseases in most cases are relatively easy to diagnose and manage, while infectious and hereditary diseases may require deeper investigation. Some diseases like endophthalmitis, eye notch syndrome and ophthalmopathy have been recorded but their causes could not be found out.

Introduction

Hepatocytes are tiny cells that constitute the primary structural unit of the liver. Periportal hepatocytes, the first to receive blood from the portal system, are particularly vulnerable to hepatotoxins and endotoxins. Periacinar hepatocytes, placed further away from the portal blood supply, are more susceptible to hypoxia, toxic metabolites and hypoperfusion. Inflammatory cells are drawn to injured hepatocytes and biliary epithelium due to the release of cytokines and inflammatory mediators. This causes additional hepatocyte necrosis and fibrosis. The liver has exceptional regenerative abilities as hepatocytes can be replaced even if only 12% remains intact.

Hepatocytes exhibit colour changes when they are laden with fat or pigments. In their f irst week of life, young turkeys and chickens typically have a lot of fat and pigments (carotenoids) deposited in the liver due to the ability of intestines in mobilizing the yolk content. It is typical to find fat vacuoles (microscopic fat deposits) within the hepatocytes at this point. A bird's liver will typically turn mahogany-brown after about seven days of life. Because of the influence of oestrogens, the hormones that are present in large concentrations once maturity is attained, the quantity of fat in the liver of adult hens increases before the age of lay. Because a large amount of fat and pigments are transferred from the liver to the oviduct for yolk formation in eggs, the majority of laying hens in a flock will typically have a pale brown or yellowish liver. When liver seems pale or yellow, histopathology is a crucial technique that can be used to establish a differential diagnosis.