eChapters

E    :    Reduction potential.    
Early induced responses    :    The early induced responses or early nonadaptive responses are a series of host defense responses that are triggered by infectious agents early in infection. They are distinct from innate immunity because there is an inductive phase, and from adaptive immunity in that they do not operate by clonal selection of rare antigen-specific lymphocytes.

D gene segments, diversity gene segments     :    D gene segments, or diversity gene segments, are short DNA sequences that join the V and J gene segments in rearranged immunoglobulin heavy-chain genes and in T-cell receptor â and ä chain genes. See gene segments.    
D loop    :    An extended loop of single-stranded DNA displaced from a duplex structure by an oligonucleotide.

C    :    Cytosine.
C domains    :    The constant regions of the polypeptide chains of immunoglobulin molecules are made up of one or more constant domains or C domains of similar structure; each immunoglobulin chain also has a single variable or V domain.

B    :    Born.     
B cell, also known as a B lymphocyte      :    One of the major types of cells in the immune system. B cells can differentiate to form memory cells or antibody-forming cells. OR A type of lymphocyte derived from bone marrow stem cells that matures into an immunologically competent cell under the influence of the bursa of Fabricius in the chicken and bone marrow in nonavian species. Following interaction with antigen, it becomes a plasma cell, which synthesizes and secretes antibody molecules involved in humoral immunity.

(+)sense RNA (plus-sense RNA)     :    A virus with a single-stranded RNA genome of the same polarity (‘sense’) as mrna.

Collection of faecal samples: To diagnose gastro-intestinal parasites of ruminants or other animals, the parasites or their eggs/larvae must be recovered from the digestive tract of animal or human or from the faecal/stool material.
 
The faecal samples for parasitological examination should be collected from the rectum of animals. If rectum samples cannot be obtained, fresh faecal samples may be collected from the pastures. Several samples should be collected and immediately dispatched to the diagnostic laboratory in suitable containers such as:

Small ruminants is a composite term used for sheep and goats. Throughout the developing countries, small ruminants make a very valuable contribution, especially to the poor in the rural areas. These contributions range from precious animal proteins (meat and milk) to fibre and skins, draught power in the highlands, food security and stable households. By and large, the importance and extent of the contributions are inadequately understood as a consequence of which these valuable genetic resources continue to be generally neglected. Research and development investments to improve the relatively low level of contribution do not match their potential importance, the contribution to nutritional security and livelihoods of the poor in rural areas. Species like goat and sheep are of short-generation interval, have a high prolificacy rate and require less land, investment and operational expenses and are better suited to the resource endowment of the poor.

Feeds and feeding of dairy animals are arguably the most important part of the dairy farm management. And it is not only what we feed that is important but how we manage our feeding is equally as critical. What we feed today not only determines the animal’s milk production but also influences their entire lactation cycle that follows. Dairy animal feeding with balanced ration influences health status, reproductive, productive performance and better economic return in organic environment, all of which are critical to a profitable and sustainable dairy business as well as welfare of the dairy farmers. Feed costs currently account for around 45 percent of total milk price on average, with concentrates representing around 35 percent and forages around 10 percent.

The livestock play a significant role in generating gainful employment in rural areas, particularly among the landless and marginal farmers. The Jammu region of state of Jammu and Kashmir possesses a huge livestock population which is maintained under different management systems. The region has a vast diversity in agro-climatic conditions (comprising low altitude, middle altitude and high altitude), and animal husbandry and pasture management practices. Despite having huge livestock, the production potentials are very low. There are various factors related with low production and among them parasitic diseases rank very high.

Small ruminant sector, after agriculture, is the second largest means for economic sustainability and livelihood in India. It contributed Rs. 32000 crore to the gross domestic product of India in 2012 -13 despite having a potential to contribute over Rs. 150,000 crore but there are certain lacunae in system which act as its growth inhibitor. Small ruminants are the main source for rural economies due to participation of women (70% of total) and weaker sections of the rural society. Thus there is urgent need for formulating policies to support the development of the small ruminant sector.
 
Sheep and goat husbandry is a tool for poverty alleviation of the rural masses because of wide adaptability with low investments, high fertility and fecundity, low feed and management costs, higher feed conversion efficiency, quick pay off and low risk in comparison to large ruminants. The above traits of small ruminants need to be exploited for economic upliftment of small farmers.

Livestock sector has emerged as one of the key components of agricultural growth in developing countries in last few decades. This sector plays a significant role in the economic progress of India as it contributes 26% to the agricultural GDP and provides employment to around 18 million people. Over 70% of the rural households in India depends on livestock farming for supplementary income and is considered as an important instrument in poverty alleviation. It provides the major extra contribution to agriculture through manure, fuel fertilizer, apart from meat and milk that grant a regular supplementary income and employment not only to producers but also to huge size of the population engaged in secondary and tertiary business related to livestock. The economy of Jammu and Kashmir is also agriculture dependent and is the main occupation of majority of the rural people who earn their livelihood from it. Census figures 2011 signify that about 73% of the population of J&K lives in rural areas and are associated with agriculture and allied sectors including livestock rearing as main occupation.

Introduction

Mankind has been utilizing different animal species from the dawn of civilization for a variety of purposes viz., production of milk, meat, wool, egg and leather. Apart from these, various animal species are also used for draught power, companionship, entertainment, research experimentation, sports, security etc. Livestock sector plays a crucial role in rural economy and livelihood. As per report of the working group on animal husbandry and dairying, 11th five year plan: 2007-12, the livestock sector employs eight percent of the countries labour force, including many small and marginal farmers, women and landless agricultural workers. Milk production alone involves more than 30 million small producers, each raising one or two cows or buffaloes. The organic fertilizer produced by the sector is an important input to crop production and dung from livestock is widely used as fuel in rural areas. Livestock also serves as an insurance substitute, especially for poor rural households; it can easily be sold during time of distress.

Helminths include the nematodes (roundworms), trematodes (flukes) and the cestodes (tapeworms). The adult worms live in intestine and discharge the eggs or larvae that comes out with the faeces. Therefore, diagnosis is based on the detection of eggs or larvae in faecal samples.

Overview of Nematode infections in humans and animals

The phylum Nematoda, (roundworms), is the second largest phylum in the animal kingdom, encompassing up to 500,000 species. Members of Nematoda are elongated, with bilaterally symmetric bodies that contain an intestinal system and a large body cavity. According to a report approximately 60 species of roundworms parasitize humans. Intestinal roundworm infections constitute the largest group of helminthic diseases in humans. According to 2005 report of World Health Organization (WHO), approximately 0.807-1.221 billion humans suffers from ascariasis, 604-795 million from trichuriasis and 576-740 million from hookworm infections worldwide.

Till twentieth century information technology was restricted to European and American countries but entering in twenty first century witnessed passage of this technology with a vast speed in all other countries making a spectrum of changes in communication and transmission of knowledge that has altogether changed scenario of whole world. Earlier communication to international scientists was costly, time consuming while now its only a click away. So is of transmitting reprints of research papers – earlier they were dispatched by mail, now these reprints and other matters are available in soft copy and are attached with e-mail that is transmitted instantly.

As the Veterinary colleges, and Parasitology being an integral part of them, are part of Agricultural universities framed on USA land grant pattern, or separated as Veterinary university imbibing the same philosophy, extension is an integral part of the system. Here, a team of the experts visit the villages to teach the villagers about the basic problems, faced by them in day to day dealing with animals. For explaining a particular problem to the villagers, the experts generally take help of the pamphlets which they have prepared. These pamphlets or extension literature deal the subject with common sense and illustrate the material with line drawings.

It is a must for the research scholars to attend scientific conferences of the Parasitology associations, after being members. It is advisable to become life-members of all three Parasitology associations, in India i.e. Indian Society of Parasitology, Lucknow, Indian Association for Advancement of Veterinary Parasitology, IVRI, Izatnagar and Indian Academy of Tropical Parasitology, JIPMER, Pondicherry. The annual conferences expose better chances to interlink with Parasitologists of the country and at times foreign scientists.

What so ever work you have done, it will not be recognized in the scientific world unless you publish it hence publishing the search work is of prime importance for a scientist. As it provides you recognition, you must pay greatest attention on quality of your research work which depends on the keenness of your observations. It is must to confirm and re-confirm your observations prior publishing them as once they are published, it will come in public domain with nothing you can do (except of publishing another paper to refute your earlier finding). As publishing the observations will form opinion about your scientific integrity and knowledge among the peers, the paper, if not cared and contained silly technical mistakes, will reflect ignorance of the workers on the subject.

What so ever you are doing as a researcher, one important task is to publish the same for scientific fraternity for establishing your view points else no body will recognize you and your competence. Your credentials are judged by the research papers published by you and its impact on scientific community. Therefore, it is must to publish what so ever you are doing to establish yourself in the scientific community and also to advance science. This implies to select a national or international journal for your research publication which has wide scientific circulation so that peers of scientific world may observe your publication. Adversely, the publication may bring you criticism if it does not stand on scientific parameters and you may lose your reputation in your profession.

After planning research problem, the next step is to start real research work. Indeed, it is said that planning of a research work is only 20% of work done while conducting the experiments is 80% to be done and is more laborious, requiring extended time and patience of the scientist. While conducting your research work,it is essential to record each and every observation of your work. These observations will be of two types. One is the subjective observations which are difficult to quantify. For example, if you are recording clinical parameters of a disease,you may record pulse, temperature, respiration in arithmetic form but clinical symptoms are subjective and require a description of the patient rather than filling tabular sheet. In describing morphology of a parasite both parameters are needed ; you will describe morphology of the parasite and will also mention measurements of different parts of the parasite. Likewise, you may like to describe weather conditions or behavior of animals, vectors at certain stage of disease while you have to mention figures in many cases. Thus your observations are clearly divided in two categories – one is subjective observation and other is recording arithmetic values.

Review of literature or consulting of literature is just beginning of a research project. The main intellectual work is to study the previous work meticulously and to draw conclusions regarding existing problems. This leads us to another intelligent part of the research i.e. planning of the research work. If you analyze what you are planning, it is only about materials to be employed and methodology of the research work (with planning of the work)- only these three parameters are under your control as results will be the outcome of these three facets while discussion will be how you consider your results in presence of previous research work. In fact, this statement of mine is more align to the sermon of “Shrimad Bhagwat Geeta” (5) where it is stated that man has control only on his actions (planning and conducting research) hence fulfill this duty without caring for the results-which in turn will depend on your analyzing the previous facts and how you have planned to solve the problem. Therefore, pay full attention on these three facts of the research.