eChapters

Introduction
 
Cardiovascular disease (CVD) is still a major cause of death in Western populations and is becoming an important cause of morbidity and mortality worldwide. Thanks to advanced medical knowledge and treatments, many patients survive an initial event. Because of that, prevention of secondary CVD is a growing task for nutritionists and other health professionals. Cardiovascular risk can be reduced by lifestyle changes, one of which is diet. There is now substantial evidence from epidemiological and clinical studies that a diet rich in fruits, vegetables, unrefined grains, fish and low-fat dairy products, and low in saturated fats and sodium, can reduce the risk of coronary heart disease and hypertension.

Introduction
 
Diabetes shows a wide range of variation in prevalence around the world and it is expected to affect 300 million by the year 2025. In a prevention framework where banning policies and educational strategies lead the interventions, functional foods (FFs) with their specific health effects could, in the future, indicate a new mode of thinking about the relationships between food and health in everyday life. Functional ingredients, such as stevioside, cinnamon, bitter melon, garlic and onion, ginseng, Gymnema sylvestre and fenugreek, have been addressed for their specific actions towards different reactions involved in diabetes development. New strategies involving the use of FF should be validated through large scale population trials, considering validated surrogate end points to evaluate the effect of FF in prevention of chronic diseases such as type 2 diabetes mellitus.

Introduction

The search for weight controlling foods began in the mid 19^th century when industrialization led to widespread obesity. Over the years, people have tried to lose weight by avoiding particular food groups like carbohydrates, eating specific foods such as cabbage soup, or adding a certain ingredient, like vinegar or grapefruit to each meal. Recently scientists have demonstrated that green tea, dairy products, and cinnamon have the potential to improve weight control by altering fat and/or carbohydrate metabolism at the sub-cellular level. Considerable research is needed, however, before these food items can be used to develop effective weight management products.

Introduction

In recent years, food scientists, nutritionists and health experts have become more inclined towards functional food components present in various food sources due to their positive influence on health, which is beyond providing the basic nutrition.Nowa days, generalconsumers are also seeking healthier food options because of nutritive food habits and awareness. Therefore, it has triggered the studyof food and deep mining of food components from nutritional and health benefit’s perspective also. Functional food ingredient can be defined as any componentwhich is more than a source of nutrient i.e. provides additional specific health benefits. Milk is well known to exert positive effect on human health, provides nutrition and widely consumed all across the globe in form of either milk or milk products. As per the definition, milk is heterogeneous blend of lacteal secretion which contains various elements that displays wide range of chemical and functional activities. It has been more than a source nutrition and supplement to different age groups either neonates, youngsters or grown up peoples (Park, 2009). It is one of the basicelements of many diets either in its native form or fermented form which every class of people can afford and had evolved as one of the important nourishment sources. Milk in its native form contains fewer bioactive components while fermentation process produces numerous secondary metabolites which possess various health-beneficial properties (Stanton et al., 2005).

In most countries there is no legislative definition of the term drawing a border line between conventional and functional foods is challenging even for nutrition and food experts. Functional foods do not have a specific place in food law; consequently there is a great deal of confusion about what they are, could or should be. A common perception is that functional foods are foodstuffs either with one or more specific added ingredients (components), or certain substances of common ingredients (components) removed and which are claimed to have a positive influence on human health or well being. The term ‘functional foods’ for this group of products is considered to be an unfortunate one since all foodstuffs are or should be functional and a more appropriate term might be helpful.

Introduction

The tenet “Let food be thy medicine and medicine be thy food,” said by Hippocrates nearly 2,500 years ago, is receiving renewed interest. In particular, there has been an explosion of consumer interest in the health enhancing role of specific foods or physiologically active food components called as functional foods [1]. Clearly, all foods are functional, as they provide taste, aroma, or nutritive value. Within the last decade, however, the term functional as it applies to food has adopted a different meaning - that of providing an additional physiological benefit beyond that of meeting basic nutritional needs.

Abstract

Functional foods and nutraceuticals are one of the fastest-growing segments of the food industry. The demand for these foods is driven by health conscious consumer and the growing awareness of the close connection between diet and health, particularly in relation to chronic diseases. Over the past five years (20082012), the Indian Nutraceuticals Market has been growing at a rapid pace and is expected to rise to US $ 5 billion by 2015. The rapid growth and development of this new industry combined with the need to protect consumer health and interests, has led to the evolution of a myriad of different regulatory frameworks and policies across multiple markets. Japan was one of the first countries to recognize a different category of healthier food products. The Japanese government formally accepted this category in the 1980s. Other developed countries viz. The EU, The US, Canada etc also regulated this sector during 1990s. In India, the Food Safety and Standards Act 2006 (FSSA) was enacted in 2006 in response to pressure from stakeholders and the food industry, transforming the regulation of food in India. Punjab state, with abundance of food grains and increasing trends in fruits and vegetables, provides options for both the producer and growth promotion in the nutraceuticals sector through partenship between research centers, private entrepreneurs and indigenous communities. Regulatory frameworks should focus on the protection of consumers, promotion of fair trade and innovation in the sector. This paper discusses functional foods and nutraceuticals as per food regulations prevalent in various countries and highlights how these regulatory frameworks play a major role in transforming the food sector.

Introduction

The health and wellness continue to drive growth in the global food industry as the consumers are constantly looking for the foods, beverages and other dietary solutions that will help them more aggressively to meet their own unique nutrition and personal health goals. Worldwide countries are going through a nutritional transition and are now affected by double burden of problems like nutritional and food security. The common alarming problems are under nutrition and specific nutrient deficiencies simultaneously coupled with imbalanced diets and chronic diseases. The problem of chronic diseases, non-communicable diseases (cardiovascular diseases, respiratory diseases, diabetes, obesity, cancer etc.) and malnutrition is more serious in the developing countries. The lack of access to health services, sufficient income, healthy and nutritious foods characterize majority of poor people in developing countries. So, food is not only the solution but also viewed as a product to enhance health and wellbeing, and it encourages the producers by supplying new goods that meet these needs. From the past decade, there has been growing consumer awareness regarding health, nutrition and the food safety which are often triggered by specific food incidents, especially in the developed countries and high-income groups in such countries. In the food industry there have been two broad trends which are hazards in the food chain and nutritional profile of the food. There has been recognition that hazards and contaminants can enter the food chain and can cause sickness, death and diseases, and so governments, often to deal with consumer and industry concerns, establish regulations and standards on food hazards including standards on pesticides, antibiotics, microbiological hazards and other chemical and physical contaminants. On the other hand, there is also a growing awareness of the health-enhancing properties for prevention and treatment of health concerns beyond the basic nutritional component of many foods.

Introduction

Increasing knowledge regarding the impact of diet on human health along with state-of-the-art technologies has led to significant nutritional discoveries, product innovations, and mass production on an unprecedented scale. In particular, naturally occurring bioactive extracts or single compounds thereof, that are believed to benefit human health, have spawned an important and dynamic new area of research resulting in substantial advances in nutritional knowledge. There is also growing awareness that dietary source and form of food may affect overall health. Suitably, the role of food as an agent for improving health has been recognized, initiating the development of new classes of food, known as functional foods (Honkanen 2009).

The concept of functional foods is to improve the general conditions of the body and decrease the risk of illness and disease. That is to say, bioactive compounds present as natural constituents or as fortificants in food having the potential to provide health benefits beyond the basic nutritional value of the product. Marine-derived nutrients and other marine bioactive components have excellent potential as functional food ingredients as they possess advantageous physiological effects, with medicinal characteristics and added health benefits such as anticancer or anti-inflammatory activity.

The marine world, due to its phenomenal biodiversity, is a rich natural resource of many biologically active compounds such as polyunsaturated fatty acids (PUFAs), sterols, proteins, polysaccharides, antioxidants and pigments. Many marine organisms live in complex habitats exposed to extreme conditions and, in adapting to new environmental surroundings, they produce a wide variety of secondary (biologically active) metabolites which cannot be found in other organisms. Moreover, considering its great taxonomic diversity, investigations related to the search of new bioactive compounds from the marine environment can be seen as an almost unlimited field.

Abstract

Seaweeds are the large marine algae that grow almost exclusively in the shallow waters at the edge of the oceans. Seaweeds are rich sources of many bioactive compounds and nutraceuticals. These factors are considered under two categories: Seaweed phytochemicals and Seaweed polysaccharides. They are rich in soluble dietary fibers, proteins, minerals, vitamins, antioxidants, phytochemicals, and polyunsaturated fatty acids, with low caloric value. The red, brown and green seaweeds have been shown to have therapeutic properties for health and disease management. Usually they are only used as gelling agent and stabilizers in the food and pharmaceutical industries, but current research has revealed their potential medicinal uses against many diseases like cancer, allergy, diabetes, oxidative stress, inflammation, thrombosis, obesity, hypertensive and other degenerative ailments. In line with other natural foods like fruits, vegetables and grains, there has been marked interest within the scientific community to assess which fractions of seaweeds may be linked to the historically observed health benefits. As consumer health and nutrition become more influential in the food industry, the use of seaweed as an ingredient is on the rise in product development. For several centuries there has been a traditional use of seaweeds as food in China, Japan and the Republic of Korea. This review undertakes successful exploration of potential of seaweed gums as an functional ingredient in a number of food applications. This addition has the potential to enhance the nutritional quality of a product and hence human health.

This chapter introduces the functional properties that make eggs valuable ingredients in food systems. It explains coagulation and heat-setting, foaming and aeration, emulsification, gelation, colour and flavour development, binding, adhesion and thickening. The effects of pH, temperature, processing conditions and other factors on functional performance are examined. Applications in bakery, confectionery, mayonnaise, sauces, meat products and other foods are discussed. The chapter demonstrates that eggs provide multiple technological functions simultaneously, making them particularly valuable and difficult to replace with a single alternative ingredient.

Abstract
 
Spray drying is used as one of the best alternatives for extracting essential constituents of fruit and vegetables. Spray drying of fruits and vegetable juice/purees, which is an excellent source of bio-functional properties into a solid phase helps to enhance their stability and controlled release in different food matrices. Spray drying along with different carrying agents helps to retain essential active compounds in fruits and vegetables. Spray drying is generally carried in three steps viz. atomization of liquid feed by suitable atomizer; drying of droplets with the help of hot air and motion of droplets. Carrier agents like maltodextrin, wax starch, Gum Arabic and microcrystalline cellulose are added to the feed to increase glass transition temperature. Chapter presents the effects of different operating parameters of spray drying as well as effects of carrier agents on the physicochemical and functional properties of spray dried fruit and vegetables powders.

Artificial intelligence offers practical solutions to agricultural problems associated with population growth, food demand, climate change and limited natural resources. This chapter introduces machine learning, deep learning, computer vision and natural language processing, together with enabling technologies such as IoT, remote sensing and cloud computing. It explains their applications in crop monitoring, disease recognition, yield forecasting, irrigation, soil assessment and livestock management. AI can improve decision-making, resource efficiency, automation and precision farming while reducing reliance on manual labour. The chapter also examines adoption barriers, including high costs, limited digital literacy, data-security concerns and weak rural infrastructure, and considers future developments in autonomous and climate-resilient farming.

Abstract
 
Food products can have moisture content as high as 90% which needs to be lowered to acceptable limits to prevent microbial growth and deteriorative reactions. Drying is one of the most common and cost effective techniques for removal of excess moisture from the food by application of heat. In addition to its role of extending the product shelf life and providing stability, drying also helps to produce variety of products from agricultural, horticultural and industrial products. But to obtain the desired quality product, adequate drying is essential which depends on type of dryer and drying technique employed which further requires proper understanding of drying process. Despite being important unit operation in food processing industry, appropriate scientific knowledge of the drying process is still limited. So, the fundamental principles and associated terminologies with drying has been discussed in detail in this chapter to have thorough understanding of the drying process. In addition, different models and calculation procedures for drying of different types of commodities has also been reviewed.

The term probiotic means “for life” and it is currently used to refer bacteria that are associated with beneficial effects for humans and animals. The credit for first observation made on the positive role of some selected bacteria was attributed to Eli Metchnikoff, the Russian born Nobel Prize recipient, worked at the Pasteur Institute in the beginning of the last century. Metchnikoff suggested that - “the dependence of the intestinal microbes on the food makes it possible to adopt measures to modify the microflora in our bodies and to replace the harmful microbes by useful microbes”. Interim Henry Tissier, a French paediatrician, observed that children with diarrhea in their stools had a low number of bacteria which are characterized by a peculiar Y shaped morphology. On the contrary, these “bifid” bacteria were abundant in healthy children. Based on these observations, Tissier suggested that “bifid” bacteria could be administered to patients with diarrhoea to help restore a healthy gut microflora. These two scientists were the first to give scientific intimation for the use of probiotics when even the term probiotics was not coined. Later in 1965, the term probiotics is coined by Lilly and Stillwell to describe substances produced by one microorganism, that stimulate the growth of another. Subsequently, Parker defined probiotics as organisms and substances that contribute to intestinal balance. Further, Fuller (1989) improved the Parker’s definition of probiotics as “live microbial feed supplements which beneficially affect the host animal by improving its intestinal microbial balance”. Havenaar and Huis in’t Veld (1992) extended the probiotic definition with the description: “A viable mono or mixed culture of microorganisms which, applied to animal or man, beneficially affects the host by improving the properties of the indigenous microflora”. At the end of the millennium, Salminen and his coworkers (1999) proposed the following definition: “probiotics are microbial cell preparations or components of microbial cells that have a beneficial effect on the health & well- being of host”. Whereas FAO/WHO (2001) defined probiotics as “living bacteria that, when administered in adequate amounts, confer a health benefit on the host”. This definition for probiotics is widely accepted.

Introduction
 
The future of functional foods is bright and there are several reasons for the growing interest in “functional” foods, such as awareness of personal health deterioration, led by busy lifestyles with poor choices of convenience foods and insufficient exercise; increased incidence of self-medication; increased level of information from health authorities and media on nutrition and the link between diet and health; scientific developments in nutrition research; and a crowded and competitive food market, characterized by pressurized margins. Now, the consumer is well aware of the relationship between diet and health. Consumers understand that the risk for chronic diseases such as heart disease, stroke, colon cancer, and type II diabetes is possibly preventable by modification in their diet pattern. This scientific progress in understanding the relationship of diet to disease, along with increasing health care costs and the consumer’s desire to initiate healthy eating and lifestyle habits, makes this a potentially fertile ground for the development of food products that meet these demands.

In spite of the problems with dosage and viability of probiotic strains, a lot more work is required for industry standardization and safety issues. However, it is noted that probiotics have considerable potential against many pathogenic and other diseases. A wide range of clinical trials are still needed to standardize and optimize the conditions. Ongoing basic research will continue to identify and characterize existing strains of probiotics, identifying strain-specific outcomes, determine optimal doses needed for certain results and assess their stability through processing and digestion.

The Indian economy, which meets its own dairy demands, has reached a turning point with its bovine breeding initiatives. The viability of this enterprise, however, depends largely on completing as many successful artificial insemination cycles at a cattle farm. Estrus behaviour observation is used to determine when artificial insemination should take place. But since not all cattle exhibit substantial estrus symptoms, insemination results are not always reliable. An estrus detecting instrument known as an Electronic Nose (eNose) is created to address these issues.

Introduction
Good Laboratory Practice (GLP) has been a cornerstone of laboratory operations, ensuring quality, reliability, and reproducibility in research and development across various fields, including pharmaceuticals, biotechnology, and environmental science. As we move further into the 21st century, the landscape of GLP is evolving rapidly, influenced by technological advancements, regulatory changes, and the increasing complexity of scientific research. This article explores future trends and innovations in GLP, delving into key areas such as automation, data management, regulatory shifts, and sustainable practices.
1. The Role of Automation in GLP
1.1 Increased Efficiency and Accuracy
One of the most significant trends in GLP is the integration of automation. Laboratory automation includes the prompt use of technology to perform tasks in a much efficient way with minimal human interventions, thus significantly increasing efficiency and accuracy of laboratory practices. Automated systems can handle repetitive tasks such as liquid handling, sample preparation, and data analysis, reducing the potential for human error.
Benefits of Automation
• Reduction of Human Error: Automation minimizes the chances of mistakes that can occur when humans perform these repetitive tasks, thereby improving the reliability of the results.
• Speed up the Research Process: For example, robotic systems can be used in drug discovery. These systems can conduct high-throughput screening, which means they can quickly test thousands of different compounds for potential effectiveness as drugs.

AI-driven animal husbandry is advancing through machine learning, computer vision, IoT, big-data analytics, wearable devices and automated equipment. This chapter considers future applications for monitoring animal health, behaviour, nutrition, reproduction and environmental conditions. Predictive systems can support early disease detection, precision feeding, improved breeding and reduced production costs. However, high implementation costs, data privacy, inadequate infrastructure and limited digital knowledge remain significant obstacles, particularly in developing regions. Future research should prioritize affordable, user-friendly and explainable technologies suited to smallholders. Ethical AI, climate adaptation, multimodal data integration, omics analysis and interdisciplinary collaboration among animal scientists, engineers, policymakers and farmers are identified as essential research directions.