eChapters

Abstract

Multiflash drying (MFD) process is based on the application of multiple cycles of heatingvacuum pulse to a solid food. Heat can be provided by convection (from hot air), conduction (by contact with a hot surface), microwaves, or by a combination of these methods. Due to the moderate temperatures applied to the drying food, and the sudden decompression step (vacuum pulse), MFD processes allow obtaining crispyanddried foods with very good nutritional and sensory properties. Vacuum pulses cause food texturization, which depends on the pressure drop rate during decompression. In fact, the dried products are similar to freezedried foods, but with more open structures, which result in higher crispness. The dehydration can be performed in relatively short processing times, when compared with traditional drying processes (e.g. solar drying, airdrying, vacuum drying and freezedrying). The short process time indicates clearly that this class of drying process presents a huge potential to the production of driedandcrisp foods at industrial scale.

Muscle structure
• All muscles are composed of muscle fibres which are the structural unit of muscles
• In turn, every single muscle fibre is made up of numerous smaller components called myofibrils
• Functional unit of myofibril is sarcomere
Connective tissues associated with muscle
• Whole muscle is surrounded by a sheath of connective tissue called epimysium
• Whole muscle is divided into muscle bundles by perimysium formed out of connective tissue septa originating from the interior surface of the epimysium separating the muscle fibres
• The perimysium contains the blood vessels and nerves

Mushrooms are most ancient, best known and greatly admired fleshy macrofungi. Mushrooms are delicacies, much sought after and greatly valued foods. Wild mushrooms are mostly found in forests, tree trunks, pastures, lawns and road side during winter season and appear at surprising speed. Mushroom hunting or gathering is a popular hobby in Western countries. The wild mushrooms may be edible or unpalatable or poisonous. Poisoning by wild mushrooms is common and may be fatal or produce merely mild gastrointestinal disturbance or slight allergic reaction. The term toad stool is popularly reserved for inedible or poisonous mushrooms, but this classification has no scientific basis. This alarming term keeps many people away from these foods. It is important that every mushroom intended for eating be accurately identified. Mushrooms vary in colour, size, shape, growth habit, yielding ability and other characteristics.

STRUCTURE: Mushrooms are the fleshy fungi which constitute a major group of lower plant kingdom. Mushroom is the conspicuous umbrella-shaped fruiting body (sporophore) of certain fungi of the order Agaricales in the class Basidiomycetes but also of some other groups. Popularly, the term mushroom is used to identify the edible sporophores. The edible reproductive part consists of a stem and a cap. Gills found on the underside of the cap, are arranged like spokes in a wheel. The gills bear multiple spores which start new fungi. The sporophore emerges from an extensive underground network of fine thread like white growth known as mycelium. The mushroom, fruit body produced basidiospores at the tip of club like structures, called basidia, which are arranged along the gills of the mushroom. Beneath the mushroom, in the soil, is the mold colony itself, consisting of a mat of intercoiled hyphae, sometimes several feet in diameter. The mushrooms first appear as white tiny ball consisting of short stem (stipe) and a cap (pileus) which begins to open up like an umbrella. The delicate membrane or Veil (velum) enveloping the cap tears off, if allowed to develop fully, and lamellae (gills) radiating from the stalk into the cap become visible. These gills become darkened as the basidiospores (seeds) develop into millions and fall in the ground for starting their life cycle once again for second generation of mushrooms.

Fungi cause diseases in plants and animals and in such diseases, the fungi actively grow and invade the body of their hosts. There is another means by which fungi can cause harm is growing on stored food material that we consume and produce toxic metabolites referred to as mycotoxins (means fungus poisons). Food is particularly susceptible to fungal infections at almost every stage of storage or production. Mycotoxin is toxic substance produced by a fungus. The term is restricted to toxins produced by fungi growing in human foods or animal feeds. The growth of the fungi in food grains leading to physical spoilage of grains and toxin production is a serious problem in developing countries. Their occurrence in food and feed has both economic and health implications, as the toxic effects in human beings, animals and other living systems were well established. The effects of poisoning by mycotoxin are referred to as mycotoxicoses.

Fundamentals of Nanotechnology in Packaging • Overview of Nanotechnology in Packaging: Nanotechnology in packaging refers to using materials manipulated at an extremely small scale (1-100 nanometers) to boost the performance and capabilities of packaging. Techniques like nanoparticles, nanofibers, and nanocomposites are integrated into packaging materials to improve their physical properties, prolong shelf life, and introduce new functions like antimicrobial features. Mechanisms and Key Materials • Nanoparticles: Small particles added to packaging to enhance strength, f lexibility, and barrier properties. Common types include silver, titanium dioxide, and zinc oxide nanoparticles. • Nanofibers: Made from substances such as chitosan, cellulose, or polymers, these fibers increase strength and are useful in active packaging coatings. • Nanoclays: Dispersed in polymers, these increase resistance to gases and moisture, enhancing barrier performance

Introduction
Antimicrobial resistance (AMR) is a mounting global crisis that threatens public health, food security, and development. The rapid spread of resistant pathogens has rendered many conventional antibiotics ineffective, leading to longer illnesses, increased mortality, and escalating healthcare costs(1)(2). The World Health Organization characterizes AMR as a top-ten global health threat, driven by overuse, misuse, and inadequate dosing of antibiotics. It already kills 700,000 people a year and is expected to kill 10 million people a year by 2050 if nothing is done about it(3). After penicillin was introduced to the market in 1941, the first signs of resistance appeared in staphylococci, streptococci, and gonococci. By 1942, Staphylococcus aureus, which was penicillin-resistant, emerged(4). Drug resistance must be effectively addressed for a few reasons, including public health, economic considerations, and the long-term viability of medicine. Maintaining the effectiveness of existing treatments for infectious diseases is an important objective(5). NDDS technologies have emerged as powerful tools to enhance the delivery, bioavailability, and targeting of antimicrobial agents, potentially reviving older antibiotics, and maximizing the efficacy of novel compounds(6). Parallelly, AI has found impactful applications in biomedical data analysis, drug discovery, and the rational design of therapies by processing complex datasets, predicting resistance patterns, and guiding the creation of new molecules. The integration of AI with NDDS marks a paradigm shift to optimizes delivery systems, guides individualized treatment plans, and advances the field towards precision medicine for infectious diseases (7). This chapter surveys the convergence of these technologies, exploring how AIenhanced NDDS platforms are reshaping the response to AMR. Additionally, it examines diverse AI models and algorithms employed in the prediction, optimisation, and management of drug resistance, enhanced by real-time case studies for thorough comprehension(fig1.).

Introduction

The act of substituting food or drink with low grade quality ingredients thereby the f inal product will fail to the meet the regulation or standards and in most cases even unfit for human consumption (Augustin et al., 2009). With demand for profit based manufacturing market, there will be increase in points of adulteration with cheaper alternatives or inferior grade ingredients in the production of food or drink (Banti, 2020)]. Adulteration is highly prevails in developing countries such as India, where about 70% of milk supply is adulterated on day to day basis (Bittar et al., 2017). It is every nation and each individual’s responsibility to provide safe and nutritious food to the consumers.

Introduction

Fruits contain various beneficial compounds that possess biological activities and can be used as pharmaceutical nutraceutical products. Most of the fruits contain polyphenolic components that can promote antioxidant potential on human health. Wild Blueberries, strawberries, plums, oranges, grapes, cherries and mangoes are rich in antioxidant. Additionally, anti-inflammatory, antibacterial, antifungal and chemopreventive effects are associated with the various fruits. Besides polyphenols, other compounds such as xanthones, carotenoids, saponins also exhibit health effects. Fruit consumption is considerably increasing in the daily diet because they supply high levels of biologically active compounds that impart health benefits beyond basic nutrition. Fruits provide an optimal mixture of antioxidants such as vitamins C and E, polyphenols and carotenoids, vitamins, phytoestrogens, glucosinolates and anthocyanins. Diets rich in fruits may help to delay the ageing processes and reduce the risk of certain types of cancer, cardiovascular diseases and other chronic diseases. The combination of vitamins, minerals, phenolic, antioxidants and fibre seems to be responsible for these effects. The most dietary components in fruits acting as antioxidants are fibre, polyphenols, conjugated isomers of linoleic acid, D-limolene, epigallocatechin, gallate, soy protein, isoflavones, vitamins A, B, C and E (group of tocopherols), calcium, selenium, chlorophyllin, alipharin, sulphides, catechin, tetrahy-drocurecumin, seasaminol, glutathione, uric acid, indoles, thiocyanates and protease inhibitors.

Introduction

Pulses are annually grown leguminous crops that yield one to twelve grains/ seeds within a pod, and are often promoted in diet owing to their low cost and many beneficial nutritional effects (Craig 2009). The United Nations general assembly has declared 2016 as the international year of pulses (Oyeyinka et al. 2016). The Food and Agriculture Organization (FAO) describes pulses as the crops that are harvested only for dry grain. This definition excludes crops that are harvested green as food sources (such as green beans and green peas), crops that are used only for sowing purposes (such as alfalfa and clover) and crops used primarily for oil extraction (such as peanuts and soybean). India is the largest producer (around 25%) of pulses in the world and the Indian subcontinent covers the leading area in terms of consumption of pulses. It was also suggested that India can also increase the production output by 30%, considering a rise in government support prices for stimulating the growth of pulses and in case of a normal monsoon season (FAOSTAT 2008). The mainly grown pulses in India include mungbean (green gram), chickpea (Bengal gram), urd bean (black gram), lentil (masur), pigeon pea (arhar), cowpea, horse gram and peas (Tiwari and Singh 2012). In the western countries, nowadays pulses are one of the preferred food sources of the population, owing to ideological reasons and interest in vegetarian diet.

Introduction

Functional elements are non-conventional biomolecules in foods that have the ability to modulate one or more body metabolic processes or pathways, leading in health advantages and well-being promotion. Research has demonstrated a connection between food, health and well-being functional elements. Consequently, functional elements have health-promoting roles connected with multiple progressive steps at various phases of disease control, from initiation to growth. They can therefore be implemented efficiently in disease therapy and prevention. Therefore, the borderline between food and medicine is becoming very thin at a moment when the role of a healthy diet in stopping non-communicable diseases is well recognized. Functional elements include plant-derived, non-nutritious and biologically active chemicals that operate in the body to avoid certain non-communicable diseases from occurring.

Food contains over 900 phytochemicals. One fruit or vegetable serving (about 120g) can contain as many as 100 distinct phytochemicals. Previously, functional elements were believed to happen predominantly only as phytochemicals in plant products including whole grains, fruits and vegetables. However, in animal goods such as milk, fermented dairy products and cold water fish, probiotics, conjugated linolenic acid, long-chain omega-3, −6 and −9 polyunsaturated fatty acids and bioactive peptides are also discovered. Usually, functional elements happen in various forms in food such as glycosylated, esterified, thiolated or hydroxylated materials. They also have numerous metabolic operations that enable positive impacts in the body on several illnesses and target tissues (Balic et al. 2020).

Introduction

The natural hazards like floods, cyclones, droughts, landslides and earthquakes are not rare or unusual phenomenon. India is among the world’s most disaster prone areas and a large part of the country is exposed to such natural hazards, which often turn into disasters causing significant disruption of socio-economic life of communities leading to loss of life and property. It would not be considered as a disaster unless it resulted in actual damage to human life or property. According to data accumulated over past 25 years, natural disasters in Asia accounts for about 40% of the world’s total disasters while the death toll ratio is about 50% and the number of people affected is about 90%. The latter figure is about 2.2 times the ratio of number of occurrences in Asia. The figures vary widely over the decades, a result that can be attributed to a few particularly terrible disasters. Such as the 1976 Tangshan Earthquake in China, which killed about 250,000, and a series of severe cyclones that hit Bangladesh in 1970 with a death toll of about 500,000. The death toll resulting from wind and flood disasters jumped by an order of magnitude in the 1990s. But this sudden increase affected Asia’s ratio to the world total by about 15 percentage points because there was a worldwide surge in this type of disaster. Clearly, there is an extreme concentration of victims of such disasters in Asia, Another substantial increase is clear in the value of damage caused by typhoons and cyclones; it is now running at 10 times the level of the 1980s. Again, however, the ratio has remained almost unchanged, at about 40%, because hurricanes in Central and North America account for more than 50% of the world total (51.2%, 58.5%, and 54.4% in the 1970s, 1980s, and 1990s,respectively). It is sadly worth noting that there has been conspicuous growth in the absolute value of damage in both Asia and the Americas.

WHO defines Disaster as “any occurrence, that causes damage, ecological disruption, loss of human life, deterioration of health and health services, on a scale sufficient to warrant an extraordinary response from outside the affected community or area”

Introduction
A natural disaster refers to a significant and harmful occurrence caused by the Earth’s natural processes. Examples of natural disasters include floods, storms, tornadoes, volcanic eruptions, earthquakes, tsunamis, and other geologic phenomena. A natural calamity can result in fatalities or destruction of property, and usually leads to economic harm, the extent of which is determined by the afflicted population’sability to bounce back and the availability of infrastructure.
Categories of Natural Disasters/ Catastrophes
Floods
A flood is the result of water overflowing and covering land. According to the EU Floods Directive, a flood is defined as the temporary  inundation of territory that istypically not submerged in water. Flooding can occur when the amount of water in ariver or lake exceeds its  capacity, causing the water to overflow and breach its normal borders. The size of a lake or other body of water may alter due to seasonal variations in precipitation and snow melt. However, it is not considered a substantial flood unlessthe water submerges land that is utilized by humans, such as villages, cities, populated areas, highways, and farms.

Forests are valuable renewable resources for humanity on Earth. The country’s forest cover has been estimated to comprise 19.39% of its entire geographical area. Forests consist primarily of trees that offer wood that can be transformed into solid, liquid, and gaseous fuels. Forests play a crucial role in regulating the Earth’s temperature by serving as carbon dioxide filters. They provide habitats and shelters for numerous species and also contribute to the visual beauty of the environment. Forests supply the necessary resources for a range of wood related industries, including pulp and paper, composite wood, rayon and other synthetic fibers, sporting goods, furniture, boat
construction, and matches. Timber plays a crucial role in the construction of buildings.Various products, such as bamboos, resins, gums, oils, fibers, medicines, katha, lac, shellac, etc., are derived from forests.
The country’s forest cover has been calculated to be 637,293 square kilometers, accounting for 19.39% of the country’s total geographic area. This falls short of the stipulated requirement, which is 30% of the entire land area. The geographic region is comprised of 11.48% dense forest, 7.76% open forest, and 0.15% mangrove. World Forest Day is observed on March 21st, while National Forest Day is celebrated on September 11th.

Natural resources are the resources present naturally in the environment. These resources are used by human being for their survival. Minerals, building stones, forests, and various energy resources are known as natural resources. Natural resources have been extracted and utilized since ancient times but as the population increased, the demand of natural resources are increasing day by day.

Introduction
Antimicrobial resistance (AMR) is increasingly recognised as a “silent pandemic,” threatening global health and development. In 2019 alone, bacterial AMR was directly responsible for 1.27 million deaths and contributed to nearly 5 million more worldwide. Projections warn that by 2050, unchecked AMR could result in 10 million annual deaths and impose a staggering economic burden of USD 100 trillion. A major driver of this crisis is the indiscriminate and often prophylactic use of antibiotics in livestock production systems, which account for a majority of global antimicrobial consumption. The One Health framework—emphasising the interconnectedness of animal, human, and environmental health—offers a strategic pathway for mitigating AMR. It requires dismantling sectoral silos and fostering collaboration among veterinarians, physicians, public health authorities, food safety regulators, and environmental scientists. Against this backdrop, NDDB has positioned itself as a frontrunner in India by embedding One Health principles into large-scale field programmes. Since 2014, NDDB has progressively promoted alternative medicine for bovine mastitis control under its Mastitis Conrol Project (MCP), subsequently expanding in 2017–18 into a broader Disease Control through Alternate Methods (DCAM) project with Ethnoveterinary Medicine (EVM) as the central pillar.
Building Up: From DCAM to DISHA as One Health Strategy
Building on the successes of MCP, DCAM, and BCP, NDDB launched the Dairy Integrated Safety and Health Action (DISHA) project for 2025–2030, DISHA consolidates NDDB’s One Health strategy by combining animal health management, zoonotic disease surveillance, and food safety monitoring. Its objectives include: managing bovine cases with EVM, organising farmer awareness programmes, training veterinarians and health workers, screening cattle as well as their owner for brucellosis, and testing bulk milk samples for aflatoxins and antibiotic residues. Importantly, DISHA also addresses emerging food system contaminants such as microplastics, per- and polyfluoroalkyl substances (PFAs), Bisphenol-A (BPA) and heavy metals, thereby broadening the scope of One Health beyond infectious diseases.

Introduction

Society is dynamic. The requirement of society varies in course of time. During the life process human being faces lots of health hazards which are mostly due to intake of various foods. So people become cautious about the intake of food and think about the quality of foods which can protect the health of human being. In ancient times people made medicines from plant extracts to protect their health. In 1989, Dr. Stephen coined the term “Nutraceuticals” which is combination of nutrition and pharmaceutical. Nutrition is required for health and pharmaceuticals provide remedy for sickness. So it is a preventive approach. Nowadays, the definition of nutraceuticals has been expanded to include vitamins, minerals, herbs and other botanicals, amino acids, and dietary substance for human use as a supplement diet (Stauffer, 1999).

Nutraceuticals are dietary supplements made only from whole foods to augment health. Currently over 470 nutraceutical and functional food products are available with documented health benefits (Brower, 1999). The patients are much aware about the side effects of chemical agents in short and long term therapy. So to avoid medicine used for small diseases, new therapies came into trend with the help of nutritional approaches i.e. “Nutraceuticals”. The use of nutraceuticals becomes easier than pharmaceuticals since nutraceuticals does not require any animal verification for its use in human. Nutraceuticals,

Functional foods and Dietary Supplements are most important concept in food science. They have distinction amongst themselves.

Introduction

The gut microbiota is the complex and dynamic community of microorganisms that includes various bacteria, fungi and other microorganisms, proliferate and lead a symbiotic/mutual relationship with the host system. These microorganisms protect the host against pathogens by unique mechanisms, helps to maintain shape and strengthen the intestinal epithelium and boost immune response. Diverse bacterial metabolites can immigrate the host bloodstream and other parts of the body via various channels in humans and animals, such as gut-microbiota-brain, gut microbiota-skin, gut-vagina, gut liver, gut-bones etc. However, many aspects of modern lifestyle would alter the gut microbiota and lead to numerous diseases including inflammatory bowel disease, diabetes mellitus, obesity, and metabolic syndrome. Probiotics and other beneficial microbes exert many beneficial effects on their hosts by modulating the gut microbiota. While the term probiotic is reserved only for well-characterised strains with clinically proven health benefits, other beneficial microorganisms include, organisms responsible for the fermentation of foods viz. yogurt, kefir, kombucha, kimchi and many others that have been shown to have distinct health benefits. Interestingly, major group of these beneficial organisms belong to lactic acid bacteria.

Nitrates and nitrites are known to have injurious effects on animals when excess amounts are ingested. Nitrites are much more toxic but nitrates are reduced to nitrites by bacterial action in the digestive tract

Nitrites (NO₂) are rarely found in plants  in appreciable amounts except under very unusual conditions such as severe disease infections; therefore, the results are usually reported in terms of nitrates (NO₃). The usual method is to determine the total nitrate and nitrite in terms of nitrate. However, the method can also be used to determine the nitrite content of a feed separately if a nitrite problem is suspected.