eChapters

Domestic livestock plays a major role in meeting the food requirement of human beings. Especially with dwindling resources, improvement in production efficiency is primary to meet the ever-increasing demand for animal protein. The role of an animal breeder is to bring about a sustained improvement in the quality and quantity of such products. Over the years, there has been an enormous improvement in the production ability of livestock and statistical analysis has played a predominant role in the application of principles of animal breeding to improve the productivity of animals. The combination of genetics and statistics developed into a separate branch of science called biometry.

The large volume, type and nature of animal breeding data and the complex nature of analytical requirement warrants additional tools for handling, storage, retrieval and solving complex equations. Accuracy, speed, computational requirement, applicability, etc., has resulted in the development of numerous software exclusive for animal breeding data analysis. The database management system is already explained in the chapter on ‘Nature of animal breeding data and database management’. This chapter gives a note on the commonly used animal breeding software.

By 2050, the global population is projected to reach approximately 9.8 billion, requiring a 70% increase in food production to meet the growing dietary demands. The livestock sector will play a crucial role in addressing this rising need through sustainable animal production, contributing to food security, poverty alleviation, public health, and food safety. To tackle the challenges posed by population growth and to achieve the United Nations Sustainable Development Goals (SDGs), technological advancements and innovations will be essential in transforming the food and agriculture sectors.

In light of these challenges, Veterinary Services are more critical than ever. They are essential for enhancing livestock health and productivity, ensuring high-quality food that meets safety standards, and mitigating risks associated with animal diseases and public health. Additionally, Veterinary Services must contribute to global efforts in addressing issues such as food security, antimicrobial resistance, climate change, and the depletion of natural resources.

Introduction

As India is the leading global economy with livestock contributing 4.66% in total GVA to Indian Economy (PIB, 2024) and ranks 1st in Milk Production, 2nd in Egg production, 5th in meat production (BAHS, 2024). Being the largest exporter of milk and meat in the world , this has led to the intensification of animal production due to the increasing demand of major livestock products (MLPs), which has led to an increasing overall use of antimicrobials. Antimicrobials are invariably used to preserve animal and public health, but also as growth promoters at a sub-therapeutic level. The overuse and misuse of antibiotics can contribute to antimicrobial resistance. The growing resistance to antimicrobial drugs could reverse the therapeutic benefits; animals’ resistance to antimicrobial drugs, reduces productivity and leads to economic losses. Unwanted antimicrobials residues may be present in products of animal origins, in animal waste contaminating soil and water and the environment. Seventy-five to ninety percent of antimicrobials used in livestock are excreted, mostly unmetabolized. AMR poses a serious threat to the safety and quality of animal origin food, food security and livelihoods. Unhealthy and unproductive animals are no longer able to generate food products of acceptable safety and quality for human consumption and can no longer contribute to income generation. Insufficient standards for residues in animal food products, reduces the livestock sectors potential of access to trade and increases public health risks (https://www.fao.org/antimicrobial-resistance/key-sectors/animal-production/ en/).

Introduction

Wound is a disruption to the epithelial integrity of the skin, extended in-depth to subcutaneous tissue and other body parts such as ligaments, muscles, blood vessels, nerves, and bone (Robson et al. 2001). An appropriate wound healing is essential for the restoration of disrupted anatomical continuity (Begum, 2000). We have observed increasing interest in research based on traditional medicines of the world in the recent era (Medina-Franco et al. 2013). Traditional and complementary medicine regains popularity not only in developing countries but also in developed countries. Common and known practices across the globe of traditional medicines include Herbal, Ayurveda, Siddha, Unani, Iranian, Islamic, Vietnamese, Chinese, Acupuncture, African and other pseudo-medical knowledge (Dorai 2012). According to World Health Organization (WHO), traditional medicine ‘the health practices, approaches, knowledge and beliefs incorporating plant, animal and mineral-based medicines, spiritual therapies, manual techniques and exercises, applied singularly or in combination to treat, diagnose and prevent illnesses or maintain well-being’. Saxena et al. (2013) reported that phytochemicals present in plants are liable for preventing disease and promoting health. Antibiotics used in the treatment of wound infections are now proved to have adverse effects in the human body and in pathogens where resistance is emerging. Attention has, therefore, turned towards extracting biologically active compounds from plant species having wound healing property (Pattanayak and Sunita, 2008).

Introduction

Canine epilepsy, a prevalent neurological disorder, significantly impacts the quality of life for both dogs and their owners. Traditional anticonvulsant therapies often yield inconsistent outcomes, necessitating the exploration of alternative treatments such as homeopathy [1][2]. Homeopathy’s individualized approach aligns with the principles of unicism, focusing on holistic care tailored to each patient’s unique symptom profile [3]. However, the subjective nature of remedy selection and response assessment poses challenges for practitioners.

The integration of Artificial Intelligence (AI) and Machine Learning (ML) offers a promising avenue to address these challenges [4]. Predictive models can analyze complex datasets to uncover patterns that guide remedy selection and treatment strategies. This study evaluates the comparative performance of Logistic Regression, Random Forest, and XGBoost in predicting treatment outcomes for canine epilepsy managed with homeopathic remedies.

Introduction

Avian medicine is a rapidly growing field, with an increasing number of exotic bird species being kept as pets. However, the unique anatomy, physiology, and behaviour of these birds present several challenges as well as new opportunities for veterinarians and researchers.Now a day’s birds are gaining popularity over dogs and cats because of various reasons listed below:

a. They are more suited in present life style as can be suited well in small spaces.

b. They require low maintenance with relative low cost of maintenance and live longer life.

c. They form very strong bonds with their owners.

Birds can be classified into different families, such as Psittaciformes, Passeriformes, Columbiformes, Piciformes, Anseriformes, Galliformes etc. containing numerous species (>10,000). The first documentation of parrot as a pet was found in Rig Veda, written more than 3000 years ago. Evidence of bird keeping is observed in ancient civilizations of Greece, Rome, China and Egypt. In Greek mythology, Raven (a crow) was mentioned as a symbol of good luck and was associated with God Apollo (God of prophecy). Crows are also considered as ancestors in Hindu mythology and food (pinda) is offered to crows during ritual of paying homage to dead persons. In most of the countries psittacine and passerine birds are preferred as pet birds.

Introduction

Mithun (Bos frontalis), or ‘Gayal’ or ‘Eso’ or ‘Sial’ or ‘Sandong’ or ‘Wei’, is a rare bovine species, exclusively found in the northeastern hill region (NEHR) of India at an altitude of 300-3000 m. It plays an important role in the socio-economic and cultural life of indigenous tribes of Arunachal Pradesh, Nagaland, Mizoram and Manipur and is aptly referred to as the ‘Pride of Northeast India’ (Mukherjee et al. 2019). Besides India, mithun population is distributed to China, Bangladesh, Thailand, Bhutan, Myanmar, and Malaysia. The Indian mithun is a medium- to large-sized majestic ruminant with a characteristic jet-black body, an ash-colored forehead, and ‘white stockings’ on all the limbs. This unique animal has a special preference for salt feeding, is a skilled browser even in steep, hilly terrain, and does not need pasture land like cattle. Mithun is primarily reared under a free range system as an important source of lean meat, rich in amino acids, proteins, PUFA, etc. On September 1, 2023, the Food Safety and Standards Authority of India (FSSAI) officially certified the mithun as a food animal (Joshi et al., 2021; Lalchamliani et al., 2024; Ramesh et al., 2024). Compared to milk from other species, mithun milk has much larger quantities of fat, lactose, solids-not fat (SNF), calcium, important vitamins A, D, and E, essential amino acids, and polyunsaturated fatty acids (Devi et al., 2023).

Introduction

A complete neurological examination is warranted whenever an equine patient displays signs consistent with neurological disorder or to establish that the horse is neurologically normal (e.g., pre-purchase examination). Neurological examination of equine patient is challenging due to their large size, which prevents veterinarian from using many of the tests used for small animals. The key to a successful neurologic examination is to do the examination in a consistent and organized fashion. It is important to develop a routine, then do it the same way each time. This approach ensures that some parts of the examination are not forgotten and it also increases the consistency of the exam as you examine more number of equine patients. A standardized examination form is a valuable aid in this and can be concise. The goals of the neurologic examination are to determine whether disease of the nervous system exists, to localize the lesion to a particular area of the nervous system, and to describe and record the responses as a baseline for future evaluations. In this paper, a complete neurological examination is described with special emphasis on field conditions.

Asiatic Elephant (Elephas maximus) is the national heritage animal of India. This particular species now exists in 13 Asian countries including India. As per 2017 census, India is home to an estimated figure of 29,964 elephants that is >60% wild population of the globe. Once distributed across the country, now they are squeezed to 14 states grouped in four regions ie., southern (14,612), north-eastern (10,139), east-central (3,128) and northern regions (2,085). There are 2675 captive elephants across different states under both private and government custody. This largest terrestrial mammal is protected under Seclude I species of Indian Wild Life Protection Act, 1972.

Both central and state Government are implementing short- and long-term programmes for health and well-being of captive as well as free-range elephants. The Central Government has established an ‘Elephant Cell’ at the Wildlife Institute of India (WII), Dehradun to provide technical inputs to the ministry for strengthening the efforts towards conservation of elephants. Add-on, the ‘Project Elephant’ was launched in 1991-92 in the Ministry of Environment, Forests and Climate Change to restore the elephant habitats and reduce their sufferings. Elephant habitats are notified as Elephant Reserves that are basic management units for elephant conservation and managements. A total of 33 Elephant Reserves has been notified in the country. A book titled, ‘Caring for elephants: Managing health and welfare in captivity’ is edited for field officers, veterinary professionals and elephant handlers.

Learning objectives

1. Recognise inflammatory cell types

2. Recognise common skin pathogens

3. Diagnostic test are best for each case

4. Gain experience in interpretation

5. Recognise important artefacts

″The most crucial step towards healing is having the right diagnosis″. While approaching a case, a clinician should follow appropriate steps in a systematic way for accurate diagnosis of dermatological disorders. A careful history is a first step to choose appropriate diagnostic tests.

Introduction

Canine atopic dermatitis (CAD) is a chronic inflammatory skin disease marked by itching (pruritus), redness (erythema), and recurrent infections. While traditionally considered an immune-mediated condition, recent studies highlight the significant role of skin barrier dysfunction in its development. A key aspect of CAD is the compromised skin barrier, which increases permeability to allergens, irritants, and microorganisms, thereby worsening the disease. The skin barrier is a complex, dynamic structure essential for protecting dogs from environmental challenges. The stratum corneum—the outermost layer of the epidermis—serves as a crucial defense against environmental insults, allergens, and pathogens. In dogs with atopic dermatitis, this barrier often becomes impaired, leading to increased transepidermal water loss (TEWL), greater allergen penetration, and secondary infections. This dysfunction both results from and contributes to the condition, creating a self-perpetuating cycle of barrier disruption, inflammation, and immune dysregulation.

As the heart diseases in companion animals is becoming common as in humans, the research in canine cardiac diseases is one of the most extensive studies in the present scenario. As per the available literature, the overall occurrence of various cardiac abnormalities ranges from 0.37 percent to 1.67 percent in various parts of the country. Whereas, in western parts of the globe, nearly 8 million dogs suffer from heart disease accounting 10% of all dogs in the United States. Heart diseases are common among older dogs; up to 75% of senior dogs have some type of heart condition, and unfortunately, most go undiagnosed due to varied reasons. The recognition of canine cardiac diseases has been delayed, and ignored on account of lack of awareness and knowledge by the owner and inadequate diagnostic facility in our country. Physical examination, radiography, electrocardiography and echocardiography are most useful diagnostic procedures employed in diagnosing the cardiac diseases in dogs. However, majority of the acquired cardiac diseases are being managed medically with one or a combination of drugs. Improved diet management and health care of companion animals have led to increased life expectancy, as a result, cardiac diseases have become pivotal causes of death for both dogs and cats. For such reason, a major objective has become to increase the quality of life by reducing the expansion of cardiac diseases via early detection of diseases and provision of effective treatment.

Renal failure is one of the most commonly presented conditions in veterinary clinics world over. Although the potential for recovery is favorable, most animals die due to multisystemic effects induced by azotemia. Hence, extracorporeal removal of endogenous and exogenous toxins is very essential for expanding the window of recovery. Hemodialysis has been used in treatment of veterinary patients for the last 50 years and is still one of the most expensive and technically demanding treatment modalities in veterinary medicine. It is an advanced extracorporeal renal replacement therapy which has recently transitioned from a clinical curiosity to a more advanced standard for management of acute kidney injury (AKI) and chronic kidney disease (CKD) in companion animals particularly dogs and cats.

In addition to eliminating selective toxins that cause AKI, regardless of renal function, hemodialysis is also effective in the removal of pharmacokinetically active soluble uremic substances in CKD to enhance life expectancy and quality of life (Singh, 2021). Other common indications of hemodialysis in veterinary medicine include fluid overload, dysregulated body fluid composition, drug overdose or intoxications (Foster, 2020; Singh et al?, 2024). Medical management alone is often insufficient to control the clinical signs and metabolic abnormalities associated with uremia when AKI is severe or when there is involvement of acute on chronic kidney disease. Consequently, animals are at risk of death within a short therapeutic window, despite the potential reversibility of AKI and the improvement of life expectancy in CKD.

Introduction

One of the remarkable advancements in veterinary medicine recently is the application of interventional cardiology techniques to treat various congenital heart diseases. In dogs and cats, congenital heart diseases can be treated much more easily and with fewer complications using minimally invasive interventional approaches, rather than through traditional open-heart surgery. Among congenital heart diseases, treatment options are available for conditions such as PDA (Patent Ductus Arteriosus), AS (Aortic Stenosis), PS (Pulmonic Stenosis), VSD (Ventricular Septal Defect), ASD (Atrial Septal Defect), extrahepatic shunt, and stem cell applications. These diseases often cannot be significantly improved by medical treatment alone, making the use of the aforementioned interventional techniques essential for effective management.

Precision medicine and personalised treatment of systemic or tumour diseases gain their acceptance and application in veterinary care, too. The application of personalised medical protocols and companion diagnostics is easier and ethically well reasoned within the veterinary medical field – and it can offer many advantageous lessons to human clinical transformation, too [1]. In vitro companion diagnostics for testing the applicability and sensitivity levels of certain kinase inhibitor and immunotherapeutic drugs offer a greatly increased efficiency for veterinary cancer patients, too. As the understanding of cancer biology has advanced, the field of veterinary oncology has grown significantly, paralleling developments in human oncology. Precision medicine is an innovative approach to disease treatment and prevention that considers individual variability in genes, environment, and lifestyle. In the context of veterinary medicine, precision medicine aims to provide tailored therapies that are specifically designed for the unique genetic and molecular profile of each animal’s cancer. This approach moves away from the traditional “one-size-fits-all” model, instead focusing on targeted treatments that maximize efficacy while minimizing side effects. Companion diagnostics, such as molecular tests, help determine whether a dog or cat is likely to respond to a particular drug. For dogs and cats, precision medicine holds great promise in improving outcomes for cancers, which are among the leading causes of death in companion animals.

Tissue Doppler Imaging

Doppler echocardiography relies on detection of the shift in frequency of ultrasound signals reflected from moving objects. With this principle, conventional Doppler techniques assess the velocity of blood flow by measuring high-frequency, low amplitude signals from small, fast-moving blood cells. In TDI, the same Doppler principles are used to quantify the higher-amplitude, lower-velocity signals of myocardial tissue motion.

There are important limitations to TD interrogation. As with all Doppler techniques, TDI measures only the vector of motion that is parallel to the direction of the ultrasound beam. In addition, TDI measures absolute tissue velocity and is unable to discriminate passive motion (related to translation or tethering) from active motion (fiber shortening or lengthening). The emerging technology of Doppler strain imaging provides a means to differentiate true contractility from passive myocardial motion by looking at relative changes in tissue velocity.

Cardiomyopathies in acts can be classified broadly as Hypertrophic cardiomyopathy and non-hypertrophic cardiomyopathies. Usually, no alarming clinical signs are detected during routine examination in the preclinical stage except cardiac murmurs in some cats with HCM. This is because, that the cats are sedentary and excellent in hiding the signs of illness from the pet parents. Hence the onset is often acute with the sudden appearance of the clinical signs linked to congestive heart failure like severe dyspnoea, cardiogenic shock, aortic thromboembolism, arrhythmias and even syncope and death

Cats with CHF will be presented with severe dyspnoea, due to fulminant pulmonary oedema and or pleural effusion. The pleural effusion associated with CHF is usually a modified transudate, some cases it may be chylous .In echocardiography ,the size of the left atrium should be determined .If the LA size is normal ,then the dyspnoea may not be of cardiac origin .The presence of B-lines in the lung area in association with LA enlargement confirms cardiogenic pulmonary oedema. Stress, anaesthesia, I/V fluids and steroids leads to decompensation and fulminant pulmonary oedema. Thoracocentesis is will be helpful if there is dyspnoea due to significant pleural effusion. At least 300ml of effusion can be usually removed. The dyspnoeic cat is very fragile and should be handled carefully. Butorphanol may be given for anxiolytic effect. Oxygen administration is beneficial. Furosemide when given intravenously has an initial venodilator effect and should be repeated as required monitoring the sleeping respiratory rate (SRR). Addition of nitro-glycerine (vasodilator) reduces preload, decreases left atrial pressure and help in reducing pulmonary oedema. If the clinical signs are suggestive of cardiogenic shock or myocardial failure, Pimobendan I/V or Dobutamine CRI should be considered.

Cytauxzoonosis is an emerging tick-borne disease of domestic cats and wild felids caused by the protozoa of the genus Cytauxzoon. The common clinical findings in affected cats are similar to other hemoparasitic infections namely anorexia, depression, anemia, vomiting, icterus, and high fever. The first reporting of feline cytauxzoonosis with four fatal cases was done by Wagner in Missouri, USA in the year 1976.

Bobcats (Lynx rufus) are recognized as the natural wild reservoir of Cytauxzoon felis with prevalence reaching up to 100% in some enzootic areas (Zieman et al., 2017). This infection is highly fatal in domestic cats with 97% mortality without treatment (Meinkoth and Kocan, 2005). However, subclinical infection in some cats has also been evidenced i.e., they were infected with C? felis but did not display the acute clinical signs of the disease before diagnosis (Brown et al., 2010 and Rizzi et al., 2015).

Several other wild felids apart from bobcats and domestic cats have been found to be affected by fatal or nonfatal Cytauxzoon sp. infection. These include lions, jaguar, cougars, pumas, ocelots, Iberian lynx, meerkats, European wild cats and Asiatic wild cat, panthers, and tigers (Jakob and Wesemeier, 1996; Rotstein et al., 1999; Yabsley et al., 2006; Andre et al., 2009; Filoni et al., 2012 and Furtado et al., 2017).

The Central Nervous System not only consists of the Brain but also involves the Spinal cord.

The spinal cord is responsible for conveying information from the Brain to the rest of the body via the peripheral nervous system. The spinal cord can be divided into 4 functional segments.

1. C1-C5 (Upper Cervical Segments)

2. C6-T2 (Brachial Plexus)

3. T3-L3 (Thoraco - Lumbar)

4. L4-S3 (Lumbo-Sacral Plexus )

It is important to note that the motor and sensory function of the pelvic limbs are not only controlled by the Lumbo-Sacral plexus but also involve the Thoraco Lumbar segments (T3-L3) of the spinal cord. It is important to understand not only the neuroanatomy, but also the functional anatomy before approaching a neurological patient.