eChapters

Genus : Durio 
Species : zibethinus Murray.
Family : Bombacaceae
Chromosome No. : 2n= 56

The exact place to which durian is indigenous is not established with certainity. The specie is said to be native to Borneo and other adjoining islands of Malay Archipelago. The species is seen growing in Sri Lanka and some other tropical countries. Outside the Malayan region durian cultivation is greatly restricted and is usually confined to the botanic gardens from study point of view. The crop has failed to move away from its native place primarily due to the fact that seeds are highly perishable which has restricted durian movement within tropical places of the world. Further due to the disagreeable flavour this fruit has not met with the favour from the Europeans. The banks of the Sarawak River are covered with many fruit trees that basically fulfill the food requirements of the local inhabitants called as Dyaks. Of the different kinds of fruit tree, durian is the most important found in abundance and is rated very highly.

Introduction

Durum or macaroni wheat (T. turgidum var. durum) is an important crop used chiefly for the production of pasta in Western Europe and North America, and two layered bread, single layered bread, burghul, couscous, pasta, frek and feed in other parts of the world (Table 1). In North Africa and the Middle East, durum is also used for producing flat breads. On a global basis only a small amount of durum wheat is used for baking of pan-style and hearth-style bread. Also, durum wheat for baking is often used in blends with common wheat. In India, durum occupies approximately 2.0 mha area and production is estimated to be around 2.5-3.0 million tones annually amounting to 3-4% of the total wheat production. The consumption of pasta is increasing at the rate of around 5% annually and currently it is estimated to be around 10 Lakh tones. The demand for pasta products may increase further due to increasing population and improving standard of living.

1. DUS TEST

A variety shall express distinct character(s) for verification, uniformity within population and stability for expression of such characters over the year and at different locations, then only its genetic purity is confirmed.

1.1. Requirements

Authentic seeds of existing varieties, pure seeds of variety under tests, list of characters to be examined and their expression.

This test is conducted in the most optimum conditions of soil and climate and the crop is exposed to the best agronomic management conditions to ensure full expression of the characters.

1.2. Distinctness

The variety under test is compared with the existing varieties (having similar plant height, growth habit, days to flowering, days to maturity and reaction to diseases) for qualitative morphological characters at seed, seedling and plant levels. Biochemical differences may also be considered. To establish the distinctness, the test is performed for 2 years for self pollinated crops.

In order to provide for the establishment of an effective system for protection of plant varieties, plant breeders’ rights and the farmers’ rights and to encourage the development of new varieties of plants it has been considered necessary to put in place a legal protection mechanism the Protection of Plant Varieties and Farmers’ Rights Act, 2001 has been enacted in India (www.plantauthority. gov.in). For the purposes of this Act, Protection of Plant Varieties and Farmers’ Rights Authority has been established and is located at NASC Complex, DPS Marg, Opp - Todapur, New Delhi-110 012.

Introduction

In order to implement the sui generis system for plant variety protection for granting PBR to a breeder or farmer or institution, DUS testing is compulsory. A new variety shall be registered, if it conforms to the criteria of novelty, distinctness, uniformity and stability. An extant variety, a variety about which there is a common knowledge shall also be registered within a specified period, if it conform such criteria as distinctness, uniformity and stability.

Once a valid application for PBR is accepted the seed / plant material of the variety will be requested for official DUS tests. These official DUS tests need to be conducted by crop based institutions on behalf of the PPV & FR authority by following universally acceptable test procedures. This necessitated in the development of test guidelines, descriptors and procedures to be followed in each crop. National Test Guidelines have been developed for 96 crops representing harmonized approach for the testing of new varieties which will form the basis for DUS examination. These National Test Guidelines contain details on i) subject of the guidelines, ii) material required, iii) conduct of tests, iv) methods and observations, v) grouping of varieties, vi) characteristics and symbols, vii) table of characteristics, viii) explanations on table of characteristics, ix) literature and x) technical questionnaire. The registration was open for 107 crop species for new variety and for 114 crop species for extant / farmers varieties.

In order to provide for the establishment of an effective system for protection of plant varieties, the rights of farmers and plant breeders and to encourage the development of new varieties of plants it has been considered necessary to recognize and protect the rights of the farmers in respect of their contribution made at any time in conserving, improving and making available plant genetic resources for the development of the new plant varieties. Moreover to accelerate agricultural development, it is necessary to protect plants breeders’ rights to stimulate investment for research and development for the development of new plant varieties.

Such protection is likely to facilitate the growth of the seed industry which will ensure the availability of high quality seeds and planting material to the farmers. India having ratified the Agreement on Trade Related Aspects of the Intellectual Property Rights has to make provision for giving effect to Agreement. To give effect to the aforesaid objectives the Protection of Plant Varieties and Farmers’ Rights Act, 2001 has been enacted in India

DUS testing is a way of determining whether a newly bred variety differs from existing varieties within the same species, or the characteristics used to establish distinctness are expressed uniformly and that these characteristics do not change over subsequent generations. Testing the distinctness, uniformity and stability (DUS) of crop varieties is a statutory requirement before varieties can be entered into the Registers of Cultivars (National Lists) and/or granted Plant Breeders’ Rights (PBR). In India, Protection of Plant Varieties and Farmers’ Right (PPV&FR) Act (2001) provides the registration of new variety of plant if it conforms to the criteria of distinctness, uniformity and stability.
Why do we need a DUS test? New (candidate) varieties should be distinct from all other varieties whose existence is a matter of common knowledge, and also sufficiently uniform and stable with respect to the characteristics used to demonstrate distinctness. ‘Common knowledge’ is broadly defined to include all known varieties, i.e. any variety entered into or subject to an application for PBR, varieties grown commercially, held in publicly accessible reference collection, or of which there is a published description (UPOV 2002).
The responsibility for DUS testing of potato varieties in India lies with the ICAR-Central Potato Research Institute (CPRI), Shimla, which is the national institute for potato research and development. Currently a set of 51 DUS characters in potato are defined by CPRI and being used for distinguishing new variety.

Pesticide Dusting

The dusting powders are low concentration ready to use type, dry formulations containing 2 to 10% pesticide. The inert material or dry diluents is talc, soapstone, attapulgite, etc. and it is non toxic. The sulphur dust is not diluted with inert material.

Leucaena leucocephala, commonly known as Subabool or Koobabool, is a fast-growing leguminous shrub often used as fodder for livestock due to its high protein content and palatability. Despite its nutritional benefits, long-termor excessive feeding of Subabool can lead to adverse health effects, including dwarfism in livestock. This condition is primarily caused by the presence of toxic compounds in the plant, notably mimosine and its breakdown products, which interfere with normal growth and metabolic functions.
Nutritional profile of subabool
Subabool is a valuable fodder crop due to its high protein content (20–30%) and digestibility. It also contains significant levels of vitamins and minerals, making it a preferred choice for supplementing livestock diets, particularly in regions with limited forage availability. However, its nutritional benefits are overshadowed by the presence of anti-nutritional factors, particularly mimosine and its derivatives.
Mimosine and its toxic effects
Mimosine, a non-protein amino acid, is the primary toxic compound in Subabool. It constitutes about 5–12% of the dry weight of the plant and can exert toxic effects on animals through:

Introduction 

It is estimated that over 795 million people, which is equivalent to one out of every nine individuals, are suffering from undernutrition. These people are mostly found in rural areas and in countries that are still in the process of developing. Technologies that are either brand new, already in use, or in the process of being developed have the potential to address all four aspects of food security. Increasing the availability of food, for instance, may be accomplished via the use of genetic modification, methods for boosting the fertility of soil, and contemporary irrigation innovation (Tripathi et al?, 2019).

Introduction

Agroforestry being old as an art and new in its scientific terms has been gaining importance in the modern era due to shift of world from technology to nature in search of resilient way of sustaining livelihood (Dutta et al., 2023, Sharma et al., 2023 Bishaw et al., 2022, Agnoletti et al., 2022). The simplicity of the agroforestry system is the flagship reason of its widespread applicability and reliability in agricultural domains. There has been change in the world perspective regarding the nature and natural resources in recent times. Although there has been forest over 31 per cent of the world’s total geographical area (FAO and UNEP, 2022) but the stabilization of ecosystem and sustainable development is difficult without subsequent interaction between the tree, crop and livestock component on farm lands, being collectively called as agroforestry.

Introduction

The most important function in the socioeconomic domain of India is played by agriculture, which is the foundation of the nation's economy. India's agriculture industry is vast, varied, and involves a lot of different players. With the use of Green Revolution technologies, it has become one of the most amazing success stories of the post-independence era. The Green Revolution enhanced rural welfare and allowed for food self-sufficiency, both of which boosted the Indian economy. In the framework of the Green Revolution, the National Agricultural Research System (NARS) played a crucial role. India boasts one of the world's biggest and most intricate agricultural research programs in terms of structure. The Imperial (now Indian) Council of Agricultural Research (ICAR) was established in 1929 on the advice of a Royal Commission on Agriculture, marking the culmination of a process that began in the 19th century and led to the creation of the current Indian agricultural research system [1].

The functioning of the agricultural sector, market dynamics, and policy consequences are all influenced by a complex web of interrelated components that make up agricultural economics dynamics. These dynamics shape the production, supply, demand, and competitiveness of agricultural products and involve the interactions between farmers, markets, technology, and government regulations [2],[5].

The concept of climate-resilient agriculture encompasses a range of approaches, including climate-smart agriculture, conservation agriculture, and agroforestry. These approaches recognize that agricultural development and growth are inextricably linked to climate change, and that farmers, policymakers, and other stakeholders must work together to promote climate-resilient agriculture practices. The dynamics of development and growth engineering in the context of climate-resilient agriculture are complex and multifaceted. They involve understanding the interactions between climate change, agricultural productivity, and rural livelihoods, as well as the role of institutions, policies, and technologies in promoting climate-resilient agriculture practices. Several driving factors are influencing the dynamic development of climate-resilient agriculture (Fig. 7.1). These include:
Increased awareness of climate change impacts on agriculture, leading to growing demand for climate-resilient agriculture practices.
• Advances in climate information and early warning systems, enabling farmers and policymakers to make more informed decisions.
• Growing recognition of the importance of soil health, biodiversity, and ecosystem services in promoting climate-resilient agriculture.
• Increased investment in climate-resilient agriculture research and development, leading to the development of new technologies and practices.
• Effective governance for growth is critical for promoting climate-resilient agriculture. This requires:
• Strong institutions and policies that support climate-resilient agriculture, including laws, regulations, and incentives.
• Inclusive coordination and collaboration among stakeholders, including farmers, researchers, policymakers, and private sector actors.
• Investment in climate information and early warning systems, as well as climate-resilient agriculture research and development.
• Support for capacity building and extension services, enabling farmers to access and adopt climate-resilient agriculture practices.
• Agricultural insurance and risk management mechanisms, enabling farmers to manage climate-related risks and uncertainties. By understanding the driving factors and governance requirements for climate-resilient agriculture, policymakers, researchers, and practitioners can work together to promote dynamic development and growth in the agricultural sector, enhancing food security, sustainability, and climate resilience.

INTRODUCTION

The aquaculture industry is regarded as one of the most advanced food production industries globally. From 2010 to 2020, it grew at an average annual rate of 4.6%, reaching 122.6 million tonnes of live weight (FAO, 2022). Sustainable aquaculture proposes numerous profits to attain economic progress through well usage of natural resources (FAO 2017). The expansions in the sustainable aquaculture business are challenging due to the inadequate number of available natural resources and industrialized effects that released to the surround environments (Costa-Pierce et al. 2012; Verdegem 2013). Particularly in intensive system, increased higher organic matter concentrations raise several future issues, including acute harmful, chronic impacts (Piedrahita 2003). Recently, Innovative biofloc technology system (BFT) is one of the most popular methods to combat these problems.

Biofloc is a climate-smart technology that relies on mass synthesis of in situ microorganisms (Ogello et al., 2021). The BFT permits high stocking densities and higher fish productivity (Ogello et al., 2021) while requiring limited or zero water exchange in to sustain the flocs (Emerenciano et al., 2017). The power of BFT aligns with the "cradle to cradle" concept that outlined by McDonough and Braungart (2002), which omits the phrase "waste”. In BFT, nitrogen wastes that generated from feces of aquatic animals and residual feeds are transformed into the microbial protein that becomes feed for the same creatures (Minaz and Kubilay 2021). Numerous microorganisms, including bacteria, microalgae, protozoa, and zooplankton, are present in biofloc particles (Ray et al. 2010a). Hence, biofloc can incorporate the diet of aquatic species, which utilises the natural productivity in the culture system as a feed source (Wasielesky et al. 2006; Emerenciano et al. 2012a). This microorganisms are recognised for their contributions to (i) preserving high water quality (Emerenciano et al., 2017), (ii) enhancing culture efficiency by lowering feed conversion ratio (FCR) and costs of feed (Hargreaves, 2006). (iii) biosecurity (Defoirdt et al., 2004), and (iv) conserving greenhouse gases (GHG) (Manan et al., 2016). These four biological roles of microorganisms in BFT units are factors of high fish production, profitability and environmental protection (Ogello et al., 2021).

5.1 GENERAL DESCRIPTION

As more is discovered about tropical soils, shifting cultivation has gained popularity as a symbol of change and showing "ingenious adaptations to unfavourable environments, based on a remarkably complete knowledge of local ecology and soil potential" (Allan 1972). The acidic tropical soils are found in about one billion ha of land in the World. Out of this, about 700 million ha of land is in the high rainfall tropics and, 300 million ha in the savanna, and practically all of it is in developing countries (IBSRAM 1987). The shifting cultivator lives in a humid tropical area with acidic soil. The use and protection of the forest to restore soil fertility is "at the heart of every agricultural system," and the tropics' swiddeners have devised a way that works (Benneh 1972). The integrated swiddener prefers field locations with existing mature forest, either "primary" or "secondary," because it recognises that it is vegetation which supply nutrients to the crop (Dove 1983a; Allan 1965; Rambo 1983; Posey 1983). The availability of nutrients to food crops increases after a burn, but these nutrients fast deplete due to leaching and erosion (Nye and Greenland 1960 and 1964). Nye and Greenland (1964) discovered the soil within the shifting cultivation to be quite variable due to fallen timber, termite mounds, and irregular ash distribution following the burning. These differences will be used to create microsites that will be planted with various crops based on the swiddeners' understanding of which crops benefit from rich soils and which are unaffected by poor soils. The field is left fallow after the cropping cycle is completed (typically 1 - 4 years), while tree crops may be harvested for years. If the site is not utilised for a long time, it will recover its fertility; if it is used too soon, degeneration will occur. It may be difficult to detect degeneration, particularly if it occurs gradually over multiple generations. It's especially tough with Shifting cultivators since they "look to be so self-sufficient, so well integrated with their surroundings" (Street 1969). The assumption is that the longer the land is left fallow, the greater the soil recovery will be. The system should be sustainable if extended fallows can be maintained. Shifting cultivators’ response to the requirement to produce food without using manures, fertilisers, or alluvial deposition is soil replenishment by fallowing (Greenland 1974). The technique works if a long fallow time is maintained; if the fallow period is shortened, soil fertility falls. Shifting agriculture is considered environmentally sound while population pressure is mild, but it is environmentally damaging when land scarcity precludes a long enough fallow interval to recover soil productivity. It's crucial to distinguish between traditional shifting cultivation and shifting agriculture in a state of disequilibrium (Watters 1971).

ABSTRACT

Dysoxylum binectariferum (Roxb.) Hook. is an evergreen tree, indigenous to India and widely distributed in different parts of India. Primarily, this plant is used in the timber market for the preparation of furniture and other wooden goods. Apart from utility in timber market, it has tremendous medicinal properties because of its unique secondary metabolites. Its hydroalcoholic extracts possess a wide range of pharmacological activities including immunomodulatory, anti-inflammatory, anti-cancer, anti-leishmanial, etc. The chromone alkaloid rohitukine, the major constituent of the plant, possess anti-fertility, anti-leishmanial, anti-adipogenic, anti-ulcerogenic, anti-cancer and immunomodulatory activities. The most extensively studied and advanced therapeutic property of this chromone alkaloid is its cyclin-dependent kinase inhibition activity, which has a direct link with its anti-cancer effect. Inspired by this natural product, two clinical candidates (flavopiridol and riviciclib) are discovered and studied in human cancer patients for treating various types of cancer. Another preclinical lead IIIM-290, which is directly derived from rohitukine via synthetic modification, has demonstrated promising oral efficacy in animal models of various cancer types. The high-value medicinal applications of this plant have necessitated the need of bringing this tree under captive cultivation. The present chapter discusses the biology pharmacological and secondary metabolites present in Dysoxylum binectariferum. The preclinical and clinical leads derived or inspired from rohitukine are also discussed in this communication.

ABSTRACT

Dysoxylum binectariferum Hook.f. (Meliaceae) is phylogenetically related to the Ayurvedic plant D. malabaricum. D. binectariferum has been identified as an enriched source of rohitukine, an alkaloid. Two synthetic flavones, flavopiridol (Alvocidib; L868275; HMR-1275; NSC 649890 of Sanofi-Aventis + NCI) and P-276-00 (Piramal) are advanced in clinical trials for the treatment of cáncer. These two molecules are considered as potent Cdk inhibitors. Cdk has been discovered as a key regulator of cell cycle. Therefore, Cdk inhibitors or modulators are of great interest to explore as novel therapeutic agents. These two molecules can be considered as rohitukine inspired drugs since their stuructural novelity originated from a compaign to develop a route of total synthesis of rohitukine. Recently a semisynthetic derivative of rohitukine; IIIM-290 has been emerged as potential preclinical cyclin-dependent kinase (Cdk) inhibitor. Moreover, phytochemical investigation of D. binectariferum yielded dysoline a new region-isomer of rohitukine. Dysoline seems to be a potent inflammatory and cytotoxic compound. Similarly, camptothecine and 9-methoxycamptothecine were isolated from Dysoxylum binectariferum for the first time by bioassay-guided fractionation. Present chapter is reviewing some original work which were carried out at CSIR-Indian Institute of Integrative Medicine, Jammu, India. The present studies focused on the phytochemistry of Dysoxylum binectariferum; dysoline, camptothecin and 9-methoxycamptothecin and medcinal chemistry and preclinical evaluation of IIIM-290 a semi-sythestic derivative of rohitukine.

The disease is characterized by irregular growth and development of hair follicles and associated glands.

Sebaceous gland hyperplasia: It is a rare disease of dogs characterized by high hair coat and underlying skin, greasiness and in mainly due to excessive greasiness followed by clumping of the hair coat.

It is characterized by irregular growth and development of hair follicles and associated glands.

Introduction
Dystopian literature has emerged as a powerful genre for exploring societal anxieties, particularly in the context of environmental degradation, social inequity, and unsustainable practices. In recent years, these narratives have become increasingly relevant as global discussions around sustainable development intensify. Dystopian works like The Hunger Games by Collins (2008) and The Road by McCarthy (2006) are not only popular cultural phenomena but also significant texts that offer critical reflections on the consequences of unsustainable practices. As Suzanne Collins writes in The Hunger Games, “Destroying things is much easier than making them,” a sentiment that captures the destructive trajectory of unsustainable practices that both novels explore. This paper aims to examine how dystopian narratives, with a particular focus on The Hunger Games and The Road, contribute to sustainable development discourse. By analyzing the themes of resource depletion, environmental control, and social inequality, this study situates these narratives within eco-critical and dystopian studies frameworks, offering a deeper understanding of how literature shapes perceptions of sustainability. Thus, in this paper, an attempt has been made to explore how dystopian literature reflects concerns about sustainability, encourages critical thinking about the future of the environment and society, and emphasizes the importance of equitable, sustainable practices for survival.
Objectives of the Study
1. To analyze how The Hunger Games and The Road depict environmental degradation, resource scarcity, and social inequality, and their relevance to sustainable development discourse.
2. To explore the role of dystopian literature in raising awareness about the consequences of unsustainable practices, particularly ecological collapse and social stratification.
3. To examine the effectiveness of using eco-criticism and dystopian studies as theoretical frameworks to understand the intersection of literature and sustainability concerns.
4. To investigate how dystopian narratives can influence public perception and policy discussions related to sustainability and ethical environmental stewardship.
5. To assess the potential of dystopian literature as a tool for advocacy in promoting sustainable development and responsible environmental practices.